The determination of the low and medium molecular weight substances in the blood serum as the additional diagnostic criterion in the cases of lethal poisoning with narcotic drugs

Obukhova L.M.

Nizhegorodskoe oblastnoe biuro sudebno-meditsinskoĭ kspertizy, Nizhniĭ Novgorod, Rossiia, 603104

Andriianova N.A.

Nizhegorodskoe oblastnoe biuro sudebno-meditsinskoĭ kspertizy, Nizhniĭ Novgorod, Rossiia, 603104

The determination of the low and medium molecular weight substances in the blood serum as the additional diagnostic criterion in the cases of lethal poisoning with narcotic drugs

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Obukhova L.M., Andriianova N.A.

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Journal: Forensic Medical Expertise. 2014;57(6): 37‑39

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Obukhova LM, Andriianova NA. The determination of the low and medium molecular weight substances in the blood serum as the additional diagnostic criterion in the cases of lethal poisoning with narcotic drugs. Forensic Medical Expertise. 2014;57(6):37‑39. (In Russ.)

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The objective of the present study was the comparative analysis of the concentrations of the low and medium molecular weight substances in the blood serum in the cases of lethal poisoning with narcotic drugs, alcoholic intoxication, and endogenous intoxication associated with various diseases. The spectrogram profile of the low and medium molecular weight substances present in the blood serum obtained in the case of lethal poisoning with narcotic drugs exhibited a peak at 260-274 nm that was not found in an analogous profile in the case of alcoholic intoxication or a disease. It is concluded that the proposed analysis can be used as an additional diagnostic criterion for the documentation of poisoning with narcotic drugs and/or other potent agents.

Keywords:

endogenous intoxication

drug poisoning

spectrogram of low and medium molecular weight substances in the blood serum

Authors:

Obukhova L.M.

Nizhegorodskoe oblastnoe biuro sudebno-meditsinskoĭ kspertizy, Nizhniĭ Novgorod, Rossiia, 603104

Andriianova N.A.

Nizhegorodskoe oblastnoe biuro sudebno-meditsinskoĭ kspertizy, Nizhniĭ Novgorod, Rossiia, 603104

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