Analysis of anamnesis, gynecological and somatic diseases in overweight pregnant women as possible risk factors for gestational diabetes mellitus

Ryabov A.Yu.

Samara State Medical University

ORCID: 0000-0003-1769-1007

Tselkovich L.S.

Samara State Medical University

ORCID: 0000-0002-0605-5104

Balter R.B.

Samara State Medical University

ORCID: 0000-0001-6724-0066

Ivanova T.V.

Samara State Medical University

ORCID: 0000-0002-6153-7456

Ibragimova A.R.

Samara State Medical University

ORCID: 0000-0002-3676-6935

Katorkina E.S.

Samara State Medical University

ORCID: 0000-0001-6931-5834

Analysis of anamnesis, gynecological and somatic diseases in overweight pregnant women as possible risk factors for gestational diabetes mellitus

Authors:

Ryabov A.Yu., Tselkovich L.S., Balter R.B., Ivanova T.V., Ibragimova A.R., Katorkina E.S.

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Journal: Russian Bulletin of Obstetrician-Gynecologist. 2023;23(3): 77‑84

DOI: 10.17116/rosakush20232303177

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To cite this article:

Ryabov AYu, Tselkovich LS, Balter RB, Ivanova TV, Ibragimova AR, Katorkina ES. Analysis of anamnesis, gynecological and somatic diseases in overweight pregnant women as possible risk factors for gestational diabetes mellitus. Russian Bulletin of Obstetrician-Gynecologist. 2023;23(3):77‑84. (In Russ.)
https://doi.org/10.17116/rosakush20232303177

Подписка 2025-2 (Russian Bulletin of Obstetrician-Gynecologist)

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OBJECTIVE

To estimate the prognostic value of history of gynecologic and somatic diseases as possible risk factors of gestational diabetes in overweight and alimentary obesity degree I women.

MATERIAL AND METHODS

A retrospective anamnestic and lifestyle analysis was performed in 214 pregnant women with a first degree overweight and alimentary obesity: 93 of them (the study group) developed GDM at different terms of pregnancy; 121 women had no carbohydrate metabolism abnormalities (the comparison group). The risk factors of GDM development were estimated in accordance with the table of risk factors developed by the authors of the draft clinical guidelines «Gestational diabetes. Diagnosis, treatment, obstetric management, and postpartum care», 2020. Examination of pregnant women in the groups was carried out in accordance with the order of the Ministry of Health of Russia №1130n of 20.10.20, «On approval of the Order of medical care in the profile «Obstetrics and gynecology» and the current clinical guidelines (protocol) «Gestational diabetes mellitus: diagnosis, treatment, postpartum monitoring», 2014.

RESULTS

No statistically significant differences were found in the structure of previous and concomitant somatic and gynecologic diseases in the patients of the study groups. The influence of social parameters such as employment was also comparable in both groups of pregnant women. Among the anamnestic parameters under review, statistically significant differences were associated with some parameters that could be classified as possible risk factors for gestational diabetes mellitus, such as low physical activity, spontaneous abortion in early gestation, and delivery of a large fetus in the anamnesis.

CONCLUSION

The presence of individual risk factors is insufficient to predict gestational diabetes mellitus in pregnant women with a history of gestational diabetes mellitus who are overweight or of first-degree obesity, but their cumulative effect, which increases the risk, must be taken into account. Further clinical and additional laboratory studies are needed to work out prognostic markers of gestational diabetes mellitus.

Keywords:

risk factors for gestational diabetes mellitus

excessive body weight and first-degree obesity

Authors:

Ryabov A.Yu.

Samara State Medical University

ORCID: 0000-0003-1769-1007

Tselkovich L.S.

Samara State Medical University

ORCID: 0000-0002-0605-5104

Balter R.B.

Samara State Medical University

ORCID: 0000-0001-6724-0066

Ivanova T.V.

Samara State Medical University

ORCID: 0000-0002-6153-7456

Ibragimova A.R.

Samara State Medical University

ORCID: 0000-0002-3676-6935

Katorkina E.S.

Samara State Medical University

ORCID: 0000-0001-6931-5834

Received:

21.02.2023

Accepted:

07.03.2023

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