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Ushkalova E.A.

Peoples’ Friendship University of Russia (RUDN University)

Zyryanov S.K.

Peoples’ Friendship University of Russia (RUDN University)

Zatolochina K.E.

Peoples’ Friendship University of Russia (RUDN University)

New approaches to the diagnosis and treatment of B12-deficiency conditions

Authors:

Ushkalova E.A., Zyryanov S.K., Zatolochina K.E.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2021;24(3): 59‑66

DOI: 10.17116/profmed20212403159

Read: 38860 times

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Table of contents

NEW APPROACHES TO THE DIAGNOSIS AND TREATMENT OF B12-DEFICIENCY CONDITIONS
NEW APPROACHES TO THE DIAGNOSIS AND TREATMENT OF B12-DEFICIENCY CONDITIONS

To cite this article:

Ushkalova EA, Zyryanov SK, Zatolochina KE. New approaches to the diagnosis and treatment of B12-deficiency conditions. Russian Journal of Preventive Medicine. 2021;24(3):59‑66. (In Russ.)
https://doi.org/10.17116/profmed20212403159

Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The results of studies carried out in recent decades in different countries of the world indicate an increase in the prevalence of vitamin B12 deficiency including its subclinical form which is the basis for searching for new approaches to the diagnosis and treatment of B12-deficiency conditions. The article discusses the features of the pharmacokinetics and pharmacodynamics of vitamin B12, the causes and risk factors for the development and clinical manifestations of its deficiency; also, it provides the modern recommendations for screening and diagnosis of vitamin B12 deficiency. It’s under discussion the usage of oral preparations containing 1000 μg of cyanocobalamin which has a number of advantages over intramuscular injections from the point of evidence-based medicine.

Keywords:

vitamin B12 deficiency
diagnosis
treatment
high-dose oral cyanocobalamin preparations

Authors:

Ushkalova E.A.

Peoples’ Friendship University of Russia (RUDN University)

Zyryanov S.K.

Peoples’ Friendship University of Russia (RUDN University)

Zatolochina K.E.

Peoples’ Friendship University of Russia (RUDN University)

Received:

11.02.2021

Accepted:

02.03.2021

Close metadata

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