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Adamyan L.V.

Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia

Stepanian A.A.

Kafedpa peppoduktivnoĭ meditsiny i xipupgii Mockovckogo univepciteta meditsiny i ctomatologii

Dementyeva V.O.

Federal State University «National Medical Reseach Center of Obstetrics, Gynecology and Perinatology» after V.I. Kulakov, Moscow, Russia

The role of minimally invasive surgery in reproduction preservation in patients with premature ovarian insufficiency (a review)

Authors:

Adamyan L.V., Stepanian A.A., Dementyeva V.O.

More about the authors

Journal: Russian Journal of Human Reproduction. 2018;24(5): 72‑76

DOI: 10.17116/repro20182405172

Read: 593 times

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Table of contents

THE ROLE OF MINIMALLY INVASIVE SURGERY IN REPRODUCTION PRESERVATION IN PATIENTS WITH PREMATURE OVARIAN INSUFFICIENCY (A REVIEW)
THE ROLE OF MINIMALLY INVASIVE SURGERY IN REPRODUCTION PRESERVATION IN PATIENTS WITH PREMATURE OVARIAN INSUFFICIENCY (A REVIEW)

To cite this article:

Adamyan LV, Stepanian AA, Dementyeva VO. The role of minimally invasive surgery in reproduction preservation in patients with premature ovarian insufficiency (a review). Russian Journal of Human Reproduction. 2018;24(5):72‑76. (In Russ.)
https://doi.org/10.17116/repro20182405172

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The articles were searched in the Medline database. Review includes the results of studies published over the past 15 years. Until now, the only possible way to achieve pregnancy in patients with POI was the IVF program with oocyte donation. However, most women, for ethical and religious reasons, insist on using their own gametes. This review describes the latest opportunities for achieving pregnancy in patients with premature ovarian failure, which have shown their clinical effectiveness. The results of studies on the in vitro activation of residual follicles by induced changes in the system of signaling pathways, proposed as an alternative to the donor programs for the treatment of infertility in POI patients, are presented. The problem of premature extinction of ovarian function is the most knowledge-intensive direction facing modern reproductive technology. The technique «In vitro activation» is a clinically applicable and effective method of infertility treatment option in POI patients.

Keywords:

premature ovarian failure
POI
folliculogenesis
reproductive potential
in vitro activation
signaling pathway

Authors:

Adamyan L.V.

Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia

Stepanian A.A.

Kafedpa peppoduktivnoĭ meditsiny i xipupgii Mockovckogo univepciteta meditsiny i ctomatologii

Dementyeva V.O.

Federal State University «National Medical Reseach Center of Obstetrics, Gynecology and Perinatology» after V.I. Kulakov, Moscow, Russia

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