Free radicals and bioantioxidants in reproductive processes (a review)

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Nikolaev A.A.

Institut obshcheĭ genetiki im. N.I. Vavilova RAN

Loginov P.V.

GBOU VPO Astrakhanskaia gosudarstvennaia meditsinskaia akademiia

Mavlutova E.B.

Astrakhan State Medical University, 121 Bakinskaya Str., Astrakhan, Russia, 414000

Beliavskaia A.A.

Otdelencheskaia bol'nitsa na st. "Smolensk" OAO RZhD

Free radicals and bioantioxidants in reproductive processes (a review)

Authors:

Nikolaev A.A., Loginov P.V., Mavlutova E.B., Beliavskaia A.A.

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Journal: Russian Journal of Human Reproduction. 2018;24(1): 21‑26

DOI: 10.17116/repro201824121-26

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To cite this article:

Nikolaev AA, Loginov PV, Mavlutova EB, Beliavskaia AA. Free radicals and bioantioxidants in reproductive processes (a review). Russian Journal of Human Reproduction. 2018;24(1):21‑26. (In Russ.)
https://doi.org/10.17116/repro201824121-26

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)

Использование инфографики авторами научных работ

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Abstract:

In this review, the sources of reactive oxygen species (ROS) and their participation in the regulation of reproductive processes are examined; the lipid composition of spermatozoa is analyzed. The positive role of ROS in the regulation of spermatogenesis is estimated. At the same time, considering the lipoperoxidation mechanism makes us conclude about the negative effect of increased levels of free radicals on cellular processes. In the future, the protective properties of fat and water-soluble antioxidants, as well as possible biocomplexes will be evaluated in a comparative aspect, taking into account the structural features of the compounds under consideration. Studying the molecular basis of biological action of natural antioxidants will allow creating biological complexes of directed action. One of such biocomplexes are the extracts from ginger rhizomes possessing antioxidant and anticarcinogenic effects. Thus, ginger and its components potentiated by other agents will allow modifying the reproductive processes, especially under adverse conditions.

Keywords:

free radicals

lipoperoxidation

spermatogenesis

antioxidants

biocomplexes

ginger

Authors:

Nikolaev A.A.

Institut obshcheĭ genetiki im. N.I. Vavilova RAN

Loginov P.V.

GBOU VPO Astrakhanskaia gosudarstvennaia meditsinskaia akademiia

Mavlutova E.B.

Astrakhan State Medical University, 121 Bakinskaya Str., Astrakhan, Russia, 414000

Beliavskaia A.A.

Otdelencheskaia bol'nitsa na st. "Smolensk" OAO RZhD

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References:

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