
Results of Menzul’s autologous skin grafting for combat surgical trauma
Журнал: Пластическая хирургия и эстетическая медицина. 2026;(1):94-102.
DOI: 10.17116/plast.hirurgia202601194
Read: 1354 раза
Abstract
OBJECTIVE
To analyze the results of Menzul’s autologous skin grafting with split-thickness mesh transplant in combat casualties.
MATERIAL AND METHODS
The study enrolled 80 wounded who underwent autologous skin grafting: group 1 — 38 (47.5%) wounded after Menzul’s autologous skin grafting, group 2 — 42 (52.5%) wounded after Tanner procedure. Both groups were comparable in age, gender, severity of injuries and location of wounds. Special features of Menzul’s autologous skin grafting were innovative mesh autologous skin graft and wound treatment according to original method “in own liquid medium”.
RESULTS
Wound epithelialization time was 13.9±0.9 (95% CI 13.6-14.3) and 20.3±1.3 (95% CI 19.9-20.8) days, respectively (p=0.001). Partial lysis of the graft was detected in 1 and 5 patients, respectively (p<0.001). After 3 months, hypertrophic scars were detected in 2 (5.7%) and 5 (11.9%) patients, respectively (p<0.001). VAS score of dressing-related pain was 2.1±0.3 and 4.5±1.1, respectively (p<0.001). The Dermatology Life Quality Index was 5.1±0.3 and 10.2±0.5, respectively (p<0.001).
CONCLUSIONS
Menzul’s autologous skin grafting provides earlier epithelization (13.9±0.9 and 20.3±1.3 days, respectively, p=0.001), lower incidence of coarse postoperative scars (11.9% and 5.7%, p<0.001) and negative cosmetic effects (p=0.0171). This procedure is preferable for restoration of skin defects after thermal and mechanical damage.
Keywords
- autodermoplasty
- skin graft
- thermomechanical injury
- skin perforator
- gunshot wound
- Menzul
Дата поступления: 29.06.2025
Дата принятия в печать: 04.09.2025
Дата публикации: 30.03.2026
- Pećanac M, Janjić Z, Komarcević A, Pajić M, Dobanovacki D, Misković SS. Burns treatment in ancient times. Med Pregl. 2013 May-June;66(5-6): 263-267. PMID: 23888738.
- Tanner JJC, Vandeput J, Olley JF. The Mesh skin graft. Plast Reconstr Surg. 1964;34:287-292.
- Singh M, Nuutila K, Collins KC, Huang A. Evolution of skin grafting for treatment of burns: reverdin pinch grafting to Tanner mesh grafting and beyond. Burns. 2017;43:1149-1154. https://doi.org/10.1016/j.burns.2017.01.015
- Hazani R, Whitney R, Wilhelmi BJ. Optimizing aesthetic results in skin grafting. Am Surg. 2012;78:151-154.
- Menzul VA. Method of treatment of deep burn wounds. Patent for invention RU2108078C1, 04/10/1998. Application No. 96116629/14 dated 08/16/1996. (In Russ.). Accessed January 08, 2025. https://yandex.ru/patents/doc/RU2108078C1_19980410
- Menzul VA. Method of graft preparation, perforator (options) for its implementation and method of treatment of burn wounds. Patent for invention RU2594446C2, 08/20/2016. Application No. 2015100669/14 dated 12.01.2015. (In Russ.). Accessed January 08, 2025. https://yandex.ru/patents/doc/RU2594446C2_20160820
- Menzul VA. Dermatome. Utility model patent RU163864U1, 08/10/2016. Application No. 2016108593/14 dated 09.03.2016. (In Russ.). Accessed January 08, 2025. https://yandex.ru/patents/doc/RU163864U1_20160810
- Kovalev AS, Menzul VA, Guban VI, Tsvigun OV, Pilnikov SA, Barkalev MA, Selivanova EA. Complex method of treatment of patients with deep burns. Meditsinskij vestnik MVD. 2017;89(4):25-29. (In Russ.).
- Voynovsky EA, Menzul VA, Rudenko TG, et al. The system of treatment of burn wounds in its own liquid medium: a monograph. Moscow; 2015:272. (In Russ.).
- Naumov PYu, Shepel RN, Kholikov IV. Primary Medical Care for Military Personnel: Legal Regulation and Problematic Aspects. Cardiovascular Therapy and Prevention. 2023;(22)S9:46-56. (In Russ.). https://doi.org/10.15829/1728-8800-2023-3885
- Baranova NN, Kuptsov SA, Naumov PYu. Problems of treatment (medical examination) of victims of armed (military) conflict. Disaster Medicine. 2025;1:24-29. (In Russ.). https://doi.org/10.33266/2070-1004-2025-1
- Sereda AP, Andrianova MA. Recommendations for research design. Traumatology and Orthopedics of Russia. 2019;25(3):165-184. (In Russ.). https://doi.org/10.21823/2311-2905-2019-25-3-165-184
- Basra MKA, Fenech R, Gatt RM, Salek MS, Finlay AY. The Dermatology Life Quality Index 1994-2007: A comprehensive review of validation data and clinical results. Br J Dermatology. 2008;159(5):997-1035.
- Khilji FA, Gonzalez M, Finlay AY. Clinical meaning of change in Dermatology Life Quality Index scores. British Journal of Dermatology. 2002; 147(Suppl 62):50.
- Ware JE, Sherbourne CD. The MOS 36-Item Short-Form Health Survey (SF-36). Med Care. 1992;30:473-483.
- WMA Declaration of Helsinki — ethical principles for medical research involving human participants. Accessed January 08, 2025. https://www.wma.net/policies-post/wma-declaration-of-helsinki
- Leal-Khouri SM, Grummer SE. Skin Grafting. In: Nouri K. Mohs Micrographic Surgery. London: Springer-Verlag. 2012:433-442. https://doi.org/10.1007/978-1-4471-2152-7_34
- Khan AA, Khan IM, Nguyen PP, Lo E, Chahadeh H, Cerniglia M, Noriega JA. Skin graft techniques. Clin Podiatr Med Surg. 2020;37:821-35. https://doi.org/10.1016/j.cpm.2020.07.007
- Olvera-Cortés V. Types of skin grafts. In: Skin Grafts for Successful Wound Closure. Gore M, ed. London, UK: IntechOpen; 2021;2:24-26. https://doi.org/10.5772/intechopen.100857
- Stone R 2nd, Saathoff EC, Larson DA, Wall JT, Wienandt NA, Magnusson S, Kjartansson H, Christy RJ, Natesan S. Comparison of Intact Fish Skin Graft and Allograft as Temporary Coverage for Full-Thickness Burns: A Non-Inferiority Study. Biomedicines. 2024 Mar 18;12(3):680. https://doi.org/10.3390/biomedicines12030680
- Pourghadiri A, Alnojeidi H, Jalili R, Kilani RT, Nabai L, Ghahary A. In Situ Forming Nutritional and Temperature Sensitive Scaffold Improves the Esthetic Outcomes of Meshed Split-Thickness Skin Grafts in a Porcine Model. Adv Wound Care (New Rochelle). 2021 Mar;10(3):113-122. https://doi.org/10.1089/wound.2019.1108
- Philandrianos C, Andrac-Meyer L, Mordon S, Feuerstein JM, Sabatier F, Veran J, Magalon G, Casanova D. Comparison of five dermal substitutes in full-thickness skin wound healing in a porcine model. Burns. 2012 Sept;38(6): 820-829. https://doi.org/10.1016/j.burns.2012.02.008
- Hartwell R, Chan B, Elliott K, Alnojeidi H, Ghahary A. Polyvinyl alcohol-graft-polyethylene glycol hydrogels improve utility and biofunctionality of injectable collagen biomaterials. Biomed Mater. 2016;11:035013. https://doi.org/10.1088/1748-6041/11/3/035013
- Karyakin NN, Klemenova IA, Luzan AS. The outcomes of lower extremities burn wounds management by using of controlled moist environment. Pirogov Russian Journal of Surgery. 2017;(7):40-43. (In Russ.). https://doi.org/10.17116/hirurgia2017740-43
- Aleman Paredes K, Selaya Rojas JC, Flores Valdés JR, Castillo JL, Montelongo Quevedo M, Mijangos Delgado FJ, de la Cruz Durán HA, Nolasco Mendoza CL, Nuñez Vazquez EJ. A Comparative Analysis of the Outcomes of Various Graft Types in Burn Reconstruction Over the Past 24 Years: A Systematic Review. Cureus. 2024 Feb 15;16(2):e54277. https://doi.org/10.7759/cureus.54277
- Potekaev NN, Frigo NV, Petersen EV. Artificial skin: types and applications. Russian Journal of Clinical Dermatology and Venereology. 2017;16(6):7-15. (In Russ.). https://doi.org/10.17116/klinderma20171667-15
- Raborn LN, Janis JE. Prevention and Treatment of Burn Scar Contracture: A Practical Review. Plast Reconstr Surg Glob Open. 2024;12:e5333. https://doi.org/10.1097/GOX.0000000000005333
- Markel JE, Franke JD, Woodberry KM, Fahrenkopf MP. Recent Updates on the Management of Split-thickness Skin Graft Donor Sites. Plast Reconstr Surg Glob Open. 2024 Sept 18;12(9):e6174. https://doi.org/10.1097/GOX.0000000000006174
Recommended articles:
Disorders of Venous and Lymphatic Outflow in Cases of Gunshot Wounds of Extremities and Use of Lymphological Therapies.Journal of Venous Disorders. 2025;19(4):267-272
Petr Petrovich Einbrodt — a pioneer of forensic ballistics in Russia (to the 200th anniversary of the first national work on gunshot wound).Forensic Medical Expertise. 2025;68(4):48-54
Surgical issues of the treatment of meningococcal disease in children.Pirogov Russian Journal of Surgery. 2025;(9):104-114
Complications of gunshot wounds and blunt injuries of the spine and spinal cord in early period.Burdenko's Journal of Neurosurgery. 2025;89(4):30-38
Adducted specific impulse as a new prognostic criterion of after-penetration local contusion trauma severity.Forensic Medical Expertise. 2025;68(2):14-20
Reconstruction of the frontal-naso-ethmoid complex after gunshot wounds of the midface.Russian Rhinology. 2024;32(3):236-242


