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Moiseev D.A.

Pirogov Russian National Research Medical University

Zueva A.A.

Pirogov Russian National Research Medical University

Kopetsky I.S.

Pirogov Russian National Research Medical University

Avdeenko O.E.

Sechenov First Moscow State Medical University (Sechenov University)

Sorokina T.R.

Russian Medical Academy of Continuous Professional Education

The fundamental foundations of periodontal aging. Part 2

Authors:

Moiseev D.A., Zueva A.A., Kopetsky I.S., Avdeenko O.E., Sorokina T.R.

More about the authors

Journal: Russian Journal of Operative Surgery and Clinical Anatomy. 2025;9(3): 62‑69

DOI: 10.17116/operhirurg2025903162

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Table of contents

THE FUNDAMENTAL FOUNDATIONS OF PERIODONTAL AGING. PART 2
THE FUNDAMENTAL FOUNDATIONS OF PERIODONTAL AGING. PART 2

To cite this article:

Moiseev DA, Zueva AA, Kopetsky IS, Avdeenko OE, Sorokina TR. The fundamental foundations of periodontal aging. Part 2. Russian Journal of Operative Surgery and Clinical Anatomy. 2025;9(3):62‑69. (In Russ.)
https://doi.org/10.17116/operhirurg2025903162

Подписка 2026 Оперативная хирургия и клиническая анатомия (Пироговский научный журнал) (Russian Journal of Operative Surgery and Clinical Anatomy)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

BACKGROUND

The aging processes affecting the body as a whole are reflected in the oral cavity. To date, there are no clear criteria for successful aging of the oral cavity. Periodontal involutional changes are multifactorial in nature, combining physiological tissue degeneration, accumulation of oxidative stress, decreased regenerative potential and comorbidity of patients. Research in this area will allow us to form new approaches to correcting age-associated conditions of the oral cavity and improve the quality of life of the aging population.

OBJECTIVE

To summarize and analyze the available scientific data on the aging of periodontal tissues.

MATERIAL AND METHODS

A systematic review of the literature data was conducted, and 5897 publications were found in international electronic databases: PubMed, Cochrane, Google Search, Ebsco, Embase, Web of Science, ScienceDirect, SciELO, and eLibrary from 2000 to 2025. The methodology of this study meets the requirements for PRISMA systematic reviews and meta-analyses.

RESULTS

Based on the selection criteria, 31 publications were selected, which included the results of studying the aging of organs and tissues of the oral cavity, and the aging of periodontal tissues.

CONCLUSION

The presented detailed systematic analysis showed that periodontal aging is a complex biological process reflecting changes in the body, including both general and tissue-specific factors.

Keywords:

aging
oral aging
periodontal aging
age-related changes
immune aging
inflammatory aging

Authors:

Moiseev D.A.

Pirogov Russian National Research Medical University

Zueva A.A.

Pirogov Russian National Research Medical University

Kopetsky I.S.

Pirogov Russian National Research Medical University

Avdeenko O.E.

Sechenov First Moscow State Medical University (Sechenov University)

Sorokina T.R.

Russian Medical Academy of Continuous Professional Education

Received:

06.05.2025

Accepted:

05.06.2025

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