BACKGROUND
The base of the skull is one of the most ancient structures of the human axial skeleton. It has a complicated anatomical structure and performs a number of important functions, the main of which are the maintenance and protection of the brain, analyzers, the relationship of structures located in the cranial cavity with the underlying departments. The study of the features of the development and structure of the base of the fetal skull is of great interest due to its significant influence on the development of adjacent areas, including the brain and spinal cord, analyzers, the face and neck area.
OBJECTIVE
The aim of the study was to obtain new data on the descriptive and quantitative anatomy and topography of the internal base of the skull in fetuses 20—22 weeks of prenatal development.
MATERIAL AND METHODS
This study was performed on head preparations from 20 human fetuses 20—22 weeks of development, from the fetal collection of the Department of Human Anatomy of Orenburg State Medical University. A set of standard morphological techniques was used in the work: macromicroscopic preparation, photographing, histotopographic method, morphometry, statistical processing.
RESULTS
The results of the study showed that in this period of intrauterine development, all the structures of the internal base of the skull already formed and covered with a dura mater. The average value of the longitudinal size of internal base of the skull in the fetuses of the studied age group was 62.41±0.7 mm, the transverse size was 48.3±0.5 mm. Already at this stage of prenatal development fetal features in the anatomy of the internal base of the skull are revealed.
CONCLUSION
The obtained data in combination with lifetime imaging methods (ultrasound, MRI), can be useful to practitioners for the diagnosis and treatment of congenital malformations in this area.