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Ryabov A.B.

Hertsen Moscow Oncology Research Center, Moscow, Russia

Trunov V.O.

Kafedra detskoĭ khirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Detskaia gorodskaia klinicheskaia bol'nitsa #13 im. N.F. Filatova, Moskva

Khomyakov V.M.

Military medical unit, Golytsino, Moscow region, Russia, P.A. Gertsen Moscow scientific and research oncologic institute, National medical research center of radiology trust, Moscow, Russia

Sobolev D.D.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Pogosyan G.S.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Polushkina O.B.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Glazunov A.A.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Khoronenko V.E.

FGAOU VO «The First Moscow State Medical University named after I.M. Sechenov» Ministry of Health of Russia, Moscow, Russia

Gorbatykh S.V.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Manukyan S.R.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Murchina A.N.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Mordvin P.A.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Gurzo Yu.D.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Intraoperative hyperthermic intraperitoneal chemotherapy in children with high-grade colon adenocarcinoma

Authors:

Ryabov A.B., Trunov V.O., Khomyakov V.M., Sobolev D.D., Pogosyan G.S., Polushkina O.B., Glazunov A.A., Khoronenko V.E., Gorbatykh S.V., Manukyan S.R., Murchina A.N., Mordvin P.A., Gurzo Yu.D.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2017;6(4): 53‑58

DOI: 10.17116/onkolog20176453-58

Views: 1107

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Table of contents

INTRAOPERATIVE HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY IN CHILDREN WITH HIGH-GRADE COLON ADENOCARCINOMA
INTRAOPERATIVE HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY IN CHILDREN WITH HIGH-GRADE COLON ADENOCARCINOMA

To cite this article:

Ryabov AB, Trunov VO, Khomyakov VM, et al. . Intraoperative hyperthermic intraperitoneal chemotherapy in children with high-grade colon adenocarcinoma. P.A. Herzen Journal of Oncology. 2017;6(4):53‑58. (In Russ.)
https://doi.org/10.17116/onkolog20176453-58

Подписка 2025-2 (P.A. Herzen Journal of Oncology)
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The paper describes a clinical case of the first successful use of intraoperative hyperthermic intraperitoneal chemotherapy by Russian surgeons in treating an 11-year-old female patient with colon adenocarcinoma. The patient underwent midline laparotomy, right hemicolectomy with intraoperative hyperthermic cytostatic perfusion. The postoperative period was uncomplicated. Adjuvant polychemotherapy was performed within the framework of the FOLFOX (fluorouracil, oxaliplatin, leucovorin) protocol. Comprehensive examination of the patient at 6 months after termination of special treatment revealed no disease progression. After 12 months, local recurrence was absent; carcinomatosis was not detected. There were no local recurrence signs or metastatic cells within 1.5 years. The specific treatment has been completed; the girl leads a full life. The given case highlights the successful application of current high technologies in pediatric cancer practice. Peritoneal carcinomatosis in children with locally advanced malignant tumors of the gastrointestinal tract can be prevented with combined treatment involving intraoperative hyperthermic cytostatic perfusion.

Keywords:

mucinous adenocarcinoma
colon cancer
intraoperative hyperthermic intraperitoneal chemotherapy
children

Authors:

Ryabov A.B.

Hertsen Moscow Oncology Research Center, Moscow, Russia

Trunov V.O.

Kafedra detskoĭ khirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Detskaia gorodskaia klinicheskaia bol'nitsa #13 im. N.F. Filatova, Moskva

Khomyakov V.M.

Military medical unit, Golytsino, Moscow region, Russia, P.A. Gertsen Moscow scientific and research oncologic institute, National medical research center of radiology trust, Moscow, Russia

Sobolev D.D.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Pogosyan G.S.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Polushkina O.B.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Glazunov A.A.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Khoronenko V.E.

FGAOU VO «The First Moscow State Medical University named after I.M. Sechenov» Ministry of Health of Russia, Moscow, Russia

Gorbatykh S.V.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Manukyan S.R.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Murchina A.N.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Mordvin P.A.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

Gurzo Yu.D.

Morozov City Children’s Clinical Hospital, Moscow Healthcare Department, Moscow, Russia

List of references:

  1. Malik R, Kamath N. Anorectal mucinous adenocarcinoma in child: a case report. Eur J Pediatr. 2011;170(11):1461-1463. https://doi.org/10.1007/s00431-011-1527-1.9
  2. Sah SP, Jain BK, Lakhey M, Rani S. Mucinous carcinoma of rectosigmoid in a 15-year-old child: a case report. Indian J Pathol Microbiol. 2002;45(1):115-117.
  3. Zamir N, Ahmed S, Akhtar J. Mucinous adenocarcinoma of colon. APSP J Case Rep. 2010;1(2):20.
  4. Salas-Valverde S, Lizano A, Gamboa Y, Vega S, Barrantes M, Santamaría S, Zamora JB. Colon carcinoma in children and adolescents: prognostic factors and outcome-a review of 11 cases. Pediatr Surg Int. 2009;25(12):1073-1076. https://doi.org/10.1007/s00383-009-2491-y
  5. Hill DA, Furman WL, Billups CA, Riedley SE, Cain AM, Rao BN, et al. Colorectal carcinoma in childhood and adolescence: a clinicopathologic review. J Clin Oncol. 2007;25(36):5808-5814. https://doi.org/10.1200/JCO.2007.12.6102
  6. Koh KJ, Lin LH, Huang SH, Wong JU. CARE — pediatric colon adenocarcinoma: a case report and literature review comparing differences in clinical features between children and adult patients. Medicine (Baltimore). 2015;94(6):e503. https://doi.org/10.1097/MD.0000000000000503
  7. Puhlmann M, Fink U, Siewert JR. Value of tumor debulking in gastrointestinal tumors. Chirurg. 1999;70(12):1408-1414.
  8. Makino M, Kaibara N, Kimura O, Nishidoi H, Koga S. Correlation between subserosal venous invasion by gastric cancer and the occurrence of liver metastasis. Am J Clin Oncol. 1989;12(5):407-410.
  9. Bozzetti F, Bonfanti G, Audisio RA, Doci R, Dossena G, Gennari L, Andreola S. Prognosis of patients after palliative surgical procedures for carcinoma of the stomach. Surg Gynecol Obstet. 1987;164(2):151-154.
  10. Santoro E, Garofalo A, Carlini M, Rinaldi G, Santoro E. Early and late results of 100 consecutive total gastrectomies for cancer. Hepatogastroenterology. 1994;41(5):489-496.
  11. Sugarbaker PH. Management of peritoneal surface malignancy using intraperitoneal chemotherapy and cytoreductive surgery. J Oncol Pract. 2016;12(10):928-935.
  12. Jacquet P, Vidal-Jove J, Zhu BW, Sugarbaker P. Peritoneal carcinomatosis from intraabdominal malignancy: natural history and new prospects for management. Acta Chir Belg. 1994;94(4):191-197.
  13. Jacquet P, Stuart OA, Chang D, Sugarbaker P H. Effects of intra-abdominal pressure on pharmacokinetics and tissue distribution of doxorubicin after intraperitoneal administration. Anticancer Drugs. 1996;7(5):596-603.
  14. Sugarbaker PH. Review of a personal experience in the management of carcinomatosis and sarcomatosis. Jpn J Clin Oncol. 2001;31(12):573-583.
  15. Beaujard AC, Glehen O, Caillot JL, Francois Y, Bienvenu J, Panteix G, et al. Intraperitonealchemohyperthermia with mitomycin C for digestive tractcancer patients with peritoneal carcinomatosis. Cancer. 2000;88(11):2512-2519.
  16. Ceelen WP, Flessner MF. Intraperitoneal therapy for peritonealtumors: biophysics and clinical evidence. Nat Rev Clin Oncol. 2010;7(2):108-115. https://doi.org/10.1038/nrclinonc.2009.217
  17. Lippmann HG, Graichen D, Sarembe B, Schmidt D, Löffler I, Schilling W, Preissler J. Clinical examination of the conception ‘86 of «Canсer Multistep-Therapie» (CMT) by M. v. Ardene. Arch Geschwulstforsch. 1976;46(7):568-609.
  18. Spratt JS, Adcock RA, Muskovin M, Sherrill W, McKeown J. Clinical delivery system for intraperitoneal hyperthermic chemotherapy. Cancer Res. 1980;40(2):256-260.
  19. Athanasoulis CA, Baum S, Rösch J, Waltman AC, Ring EJ, Smith JC Jr, et al. Mesenteric arterial infusions of vasopressin for hemorrhage from colonic diverticulosis. Am J Surg. 1975;129(2):212-216.
  20. Storm FK. Clinical hyperthermia and chemotherapy. Radiol Clin North Am. 1989;27(3):621-627.
  21. Kunisaki C, Shimada H, Nomura M, Matsuda G, Otsuka Y, Akiyama H. Therapeutic strategy for signet ring cell carcinoma of the stomach. Br J Surg. 2004;91(10):1319-1324.
  22. Kochi M, Fujii M, Kanamori N, Kaiga T, Takahashi T, Kobayashi M, Takayama T. Neoadjuvant chemotherapy with S 1 and CDDP in advanced gastric cancer. J Cancer Res Clin Oncol. 2006;132(12):781-785.
  23. Hayes-Jordan A, Green H, Lin H, Owusu-Agyemang P, Mejia R, Okhuysen-Cawley R, et al. Cytoreductive surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for children, adolescents, and young adults: the first 50 cases. Ann Surg Oncol. 2015;22(5):1726-1732. https://doi.org/10.1245/s10434-014-4289-y
  24. Seitz G, Fuchs J, Königsrainer I, Warmann SW, Königsrainer A, Beckert S. Cytoreductive surgery and HIPEC for peritoneal malignancies in children. Zentralbl Chir. 2014;139(6):607-612. https://doi.org/10.1055/s-0034-1383240
  25. M.D. Anderson Cancer Center. Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for adolescent and young adults with desmoplastic small round cell tumor. ClinicalTrials.gov Identifier: NCT01277744.

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