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Chernyakova O.I.

Mechnikov North-Western State Medical University

Suvorova A.A.

Mechnikov North-Western State Medical University

Vashkevich A.A.

Mechnikov North-Western State Medical University

Raznatovsky K.I.

Mechnikov North-Western State Medical University

Reztsova P.A.

Mechnikov North-Western State Medical University

Alikbaev T.Z.

Pirogov Clinic of High Medical Technologies of the Saint Petersburg State University

Actinic keratosis. Features of pathogenesis, modern approaches to diagnosis and therapy

Authors:

Chernyakova O.I., Suvorova A.A., Vashkevich A.A., Raznatovsky K.I., Reztsova P.A., Alikbaev T.Z.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2025;24(2): 227‑234

DOI: 10.17116/klinderma202524021227

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Table of contents

ACTINIC KERATOSIS. FEATURES OF PATHOGENESIS, MODERN APPROACHES TO DIAGNOSIS AND THERAPY
ACTINIC KERATOSIS. FEATURES OF PATHOGENESIS, MODERN APPROACHES TO DIAGNOSIS AND THERAPY

To cite this article:

Chernyakova OI, Suvorova AA, Vashkevich AA, Raznatovsky KI, Reztsova PA, Alikbaev TZ. Actinic keratosis. Features of pathogenesis, modern approaches to diagnosis and therapy. Russian Journal of Clinical Dermatology and Venereology. 2025;24(2):227‑234. (In Russ.)
https://doi.org/10.17116/klinderma202524021227

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Actinic keratosis (AK, solar keratosis) is a common chronic skin disease that develops as a result of intraepidermal proliferation of atypical keratinocytes and is the precursor of squamous cell skin carcinoma (SCSC). Most often AK is localized on the skin areas exposed to long-term insolation and is usually a flat erythematosquamous plaque or spot with white or yellowish scales on the surface, slightly painful when scraping. Skin cancer incidence occupies the first place among all malignant neoplasms in the Russian Federation. The problem of AK occurrence can be faced by doctor of any specialty. Lesions in AK require timely diagnosis and treatment due to their potential transformation into invasive squamous cell carcinoma. However, the etiology and mechanisms underlying the pathogenesis of AK are not fully studied, clinical recommendations and patient management algorithms are not developed, therefore this disease is a topical problem in dermatovenereology. The article discusses the features of AK etiology and pathogenesis, clinical and dermatoscopic characteristics of this disease, as well as modern approaches to its treatment.

Keywords:

actinic keratosis
solar keratosis
squamous cell skin carcinoma
dermatoscopy

Authors:

Chernyakova O.I.

Mechnikov North-Western State Medical University

Suvorova A.A.

Mechnikov North-Western State Medical University

Vashkevich A.A.

Mechnikov North-Western State Medical University

Raznatovsky K.I.

Mechnikov North-Western State Medical University

Reztsova P.A.

Mechnikov North-Western State Medical University

Alikbaev T.Z.

Pirogov Clinic of High Medical Technologies of the Saint Petersburg State University

Received:

25.03.2024

Accepted:

17.02.2025

Close metadata

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