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Titov K.S.

Moscow Clinical Scientific and Practical Center of Moscow Healthcare Department, Moscow, Russia

Krasnorutskiy A.V.

Moscow Clinical Scientific Center, Moscow, Russia

Nagaeva M.V.

Moscow Clinical Scientific Center, Moscow, Russia

Non-surgical treatment of basal cell skin cancer (in Russian only)

Authors:

Titov K.S., Krasnorutskiy A.V., Nagaeva M.V.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2019;18(1): 13‑17

DOI: 10.17116/klinderma20191801113

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To cite this article:

Titov KS, Krasnorutskiy AV, Nagaeva MV. Non-surgical treatment of basal cell skin cancer (in Russian only). Russian Journal of Clinical Dermatology and Venereology. 2019;18(1):13‑17. (In Russ.)
https://doi.org/10.17116/klinderma20191801113

 
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The annual increase in incidence of cancer with the localization of cancerogenic process on the skin ranges from 3 to 10%. In the structure of oncological morbidity in Russia, malignant skin tumors occupy the second place in terms of incidence (11—12%). Basal cell carcinoma (BSC) accounts for up to 80% of all malignant epithelial skin tumors. The article presents a review of the literature on non-surgical methods of treating BSC, including the most important out of numerous conservative treatment strategies and effective methods of treatment. The outcomes of treatment of BSC using photodynamic (PDT), radiation, local drug therapy, systemic chemotherapy and immunotherapy are presented. Statistical data on the recurrence of BSC after various methods of conservative treatment are described and compared with the frequency of recurrence after surgical treatment. The treatment options for inoperable patients with systemic chemotherapy with Vismodegib and Sondegib, immunotherapy with recombinant interferons alpha-2b, reaferon, viferon (Russia) and intron A (USA) are reviewed. Statistically reliable data on the treatment of BSC using various non-surgical methods are given. The conclusions about the feasibility of using conservative methods of treating BSC in clinical practice are presented.

Keywords:

BSC
basal cell carcinoma
conservative treatment of BSC
non-surgical methods of treatment of BSC

Authors:

Titov K.S.

Moscow Clinical Scientific and Practical Center of Moscow Healthcare Department, Moscow, Russia

Krasnorutskiy A.V.

Moscow Clinical Scientific Center, Moscow, Russia

Nagaeva M.V.

Moscow Clinical Scientific Center, Moscow, Russia

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