Analysis of antibiotic resistance of Neisseria Gonorrhoeae strains isolates from residents of the Republic of Mordovia

Baĭtiakov V.V.; Syrkina M.G.; Vlasova S.A.

doi:https://doi.org/10.17116/klinderma201716324-27

Baĭtiakov V.V.

FGBOU VPO "Mordovskiĭ gosudarstvennyĭ universitet im. N.P. Ogareva"

Syrkina M.G.

FGBOU VO «Natsional'nyj issledovatel'skij Mordovskij gosudarstvennyj universitet im. N.P. Ogareva» Minobrnauki Rossii, Saransk, Rossija, 430000

Vlasova S.A.

FGBOU VO «Natsional'nyj issledovatel'skij Mordovskij gosudarstvennyj universitet im. N.P. Ogareva» Minobrnauki Rossii, Saransk, Rossija, 430000

Analysis of antibiotic resistance of Neisseria Gonorrhoeae strains isolates from residents of the Republic of Mordovia

Authors:

Baĭtiakov V.V., Syrkina M.G., Vlasova S.A.

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Journal: Russian Journal of Clinical Dermatology and Venereology. 2017;16(3): 24‑28

DOI: 10.17116/klinderma201716324-27

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To cite this article:

Baĭtiakov VV, Syrkina MG, Vlasova SA. Analysis of antibiotic resistance of Neisseria Gonorrhoeae strains isolates from residents of the Republic of Mordovia. Russian Journal of Clinical Dermatology and Venereology. 2017;16(3):24‑28. (In Russ.)
https://doi.org/10.17116/klinderma201716324-27

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)

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Abstract:

In modern literature, there are several reports on the regional characteristics of antibiotic resistance of gonococci. Objective. The study was aimed at evaluating antibiotic resistance of gonococcal cultures isolated from the urogenital tract of residents of the Republic of Mordovia. Material and methods. We studied antibiotic resistance of Neisseria gonorrhoeae strains isolated from the urogenital tract of 50 residents (38 males and 12 females) of the Republic of Mordovia using disk diffusion test. Results. We found high resistance of the studied cultures to trimethoprim (75.0%), kanamycin (66.6%), azithromycin (56%), clarithromycin (53.8%), and roxithromycin (50.0%); low resistance to ceftriaxone (6.3%), ofloxacin (16.7%), and ciprofloxacin (20%). N. gonorrhoeae cultures found in microbial associations (simultaneous growth on the nutrient media of Staphylococcus aureus or mixed microflora) were more resistant to kanamycin, doxycycline, amoxicillin, clarithromycin, pefloxacin, gentamicin, ofloxacin (in all these cases, p<0.001), and azithromycin (p<0.05). Conclusion. None of the tested antibiotics complies with WHO criteria (no more than 5% of resistant cultures) for the drug product that could be used for empiric therapy of gonorrhea. It is useful to study the impact of microbial associations on the level of antibiotic resistance of gonococcus.

Keywords:

gonorrhea

gonococcus

Neisseria gonorrhoeae

anti-microbial agents

antibiotic resistance

the Republic of Mordovia

Authors:

Baĭtiakov V.V.

FGBOU VPO "Mordovskiĭ gosudarstvennyĭ universitet im. N.P. Ogareva"

Syrkina M.G.

FGBOU VO «Natsional'nyj issledovatel'skij Mordovskij gosudarstvennyj universitet im. N.P. Ogareva» Minobrnauki Rossii, Saransk, Rossija, 430000

Vlasova S.A.

FGBOU VO «Natsional'nyj issledovatel'skij Mordovskij gosudarstvennyj universitet im. N.P. Ogareva» Minobrnauki Rossii, Saransk, Rossija, 430000

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References:

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