Preventative repair of postoperative ventral hernia considering the markers of connective tissue dysplasia

Lazarenko V.A.; Ivanov S.V.; Ivanov I.S.; Tsukanov A.V.; Goryainova G.N.; Obiedkov E.G.

doi:https://doi.org/10.17116/hirurgia201908112

Lazarenko V.A.

Kursk State Medical University, Ministry of Health of Russia, Kursk, Russia

Ivanov S.V.

State Research Institute for Complex Issues of Cardiovascular Diseases Municipal Budget Healthcare Institution, Kemerovo, Russia

Ivanov I.S.

Kursk State Medical University ,Department of surgical diseases №1

Tsukanov A.V.

Kursk State Medical University ,Department of surgical diseases №1

Goryainova G.N.

Kursk State Medical University, Kursk, Russia

Obiedkov E.G.

Kursk State Medical University ,Department of surgical diseases №1

Preventative repair of postoperative ventral hernia considering the markers of connective tissue dysplasia

Authors:

Lazarenko V.A., Ivanov S.V., Ivanov I.S., Tsukanov A.V., Goryainova G.N., Obiedkov E.G.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2019;(8): 12‑16

DOI: 10.17116/hirurgia201908112

Read: 986 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Lazarenko VA, Ivanov SV, Ivanov IS, Tsukanov AV, Goryainova GN, Obiedkov EG. Preventative repair of postoperative ventral hernia considering the markers of connective tissue dysplasia. Pirogov Russian Journal of Surgery. 2019;(8):12‑16. (In Russ.)
https://doi.org/10.17116/hirurgia201908112

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

Close metadata

Recommended articles:

Comparative analysis of longitudinal and transverse minilaparotomy during colon cancer surgery. Pirogov Russian Journal of Surgery. 2025;(4):71-78

CT imaging in the treatment of ventral hernias. Pirogov Russian Journal of Surgery. 2025;(5):86-95

Hybrid wound coating in rehabilitation of severe thermal burns. (An experimental study). Problems of Balneology, Physiotherapy and Exercise Therapy. 2024;(6-2):40-49

Modern methods of correction of age-related changes in the female body. Plastic Surgery and Aesthetic Medicine. 2025;(1):90-96

Combination of gothic palate and pes cavus — pattern or coincidence?. Russian Journal of Stomatology. 2025;(3):74-80

Connective tissue deficiency in the pathogenesis of anterior abdominal wall hernias and modern diagnostic approaches to improve hernioplasty outcomes. Russian Journal of Evidence-Based Gastroenterology. 2025;(3):86-94

Abstract:

Objective — to define the indication for preventive mesh implantation in patients scheduled for laparotomy. Material and methods. There were 108 patients divided into the control (52 patients without anterior abdominal wall hernia) and the main (56 patients with ventral hernia) groups. Results. Predominance of collagen type III over type I was observed in patients older 60 years in the main group. The maximum ratio of collagen types I and III was 1.4 in the main group. The minimum number of inter-fiber spaces (n=5) was noted in patients aged 30—40 years. The maximum density of connective tissue was 250 pixels per inch. Conclusion. Analysis of connective tissue structures revealed some important age-related features and markers of connective tissue dysplasia in the main group. An indication for preventive mesh implantation in patients scheduled for laparotomy was determined.

Keywords:

postoperative hernia

connective tissue dysplasia

collagen

Authors:

Lazarenko V.A.

Kursk State Medical University, Ministry of Health of Russia, Kursk, Russia

Ivanov S.V.

State Research Institute for Complex Issues of Cardiovascular Diseases Municipal Budget Healthcare Institution, Kemerovo, Russia

Ivanov I.S.

Kursk State Medical University ,Department of surgical diseases №1

Tsukanov A.V.

Kursk State Medical University ,Department of surgical diseases №1

Goryainova G.N.

Kursk State Medical University, Kursk, Russia

Obiedkov E.G.

Kursk State Medical University ,Department of surgical diseases №1

Close metadata

References:

Nelyubin PS, Galota EA, Timoshin AD. Current tendencies in surgical treatment of patients with postoperative and recurrent ventral hernias. Hirurgiya. Zhurnal im. NI Pirogova. 2007;7:69-74. (In Russ.)
Timoshin AD, Shestakov AL, Golota EA.Results of surgical treatment of postoperative ventral hernias. Vestnik gerniologii. 2006;3(11):43. (In Russ.)
Scherbakov NV. Laparoscopic treatment of postoperative ventral hernias (literature review). Jendoskopicheskaya hirurgiya. 2010;3:35-39. (In Russ.)
Jettinger AP, Stupin VA, Nesterenko YuA, Amirov MV, Titkova SM, Krot J, Dzhafarov JT. State of connective tissue in patients with postoperative ventral hernias. Gerniologija. 2006;3(11):51. (In Russ.)
Klinge U, Si ZY, Zheng H, et al. Collagen I/III and matrix metalloproteinases (MMP) 1 and 13 in the fascia of patients with incisional hernias. J Invest Surg. 2001;14:47-54. https://doi.org/10.1080/089419301750072202
Pans A, Albert A, Lapiere CM, Nusgens B. Biochemical study of collagen in adult groin hernias. J Surg Res. 2001;95:107-111. https://doi.org/10.1006/jsre.2000.6024
Ozdogan M, Yildiz F, Gurer A, Orhun S, Kulacoglu H, Aydin R. Changes in collagen and elastic fiber contents of the skin, rectus sheath, transversalis fascia and peritoneum. Bratisl Lek Listy. 2006;107(6):235-238.
Zheng H, Si Z, Kasperk R, et al. Recurrent inguinal hernia: disease of the collagen matrix? World J Surg. 2002;26(4):401-408. https://doi.org/10.1007/s00268-001-0239-5
Chernyh AV, Lyubykh EN, Zakurdaev EI. Modern views on surgical anatomy of the inguinal canal at the inguinal hernias. Vestnik novykh meditsinskikh tekhnologiy. 2014;21(3):112-115. (In Russ.). https://doi.org/10.12737/5913
Ivanov IS, Lazarenko VA, Ivanov SV, Goryainova GN, Tarabrin DV. Analysis of the Ratio of Collagen Types I and III in Skin and Aponeurosis in Patients with Ventral Hernias. Vestnik jeksperimental’noy i klinicheskoy khirurgii. 2013;3(20):330-333. (In Russ.)
Rybachkov VV, Shormanov CB, Maslov EV, Kabanov EV. Clinical-morphological estimation of methods of plastics of postoperative ventral hernias. Gerniologiya. 2006;3(11):35-36. (In Russ.)