Aim. To study the safety of early discharge after endovascular coronary artery treatment (less than 24 hours after the procedure) with traditional Holter monitoring of ECG or telemetric ECG monitoring during the first 24 hours after discharge from the hospital. Materials and methods. 363 patients with chronic ischemic heart disease who underwent endovascular coronary artery treatment with overnight hospitalization were included in the study. Holter ECG monitoring was carried out according to a standard procedure. The records were analyzed in a semi-automatic mode with manual processing of the results of the morphological classification of QRS complexes and artifacts. Telemetry ECG monitoring was carried out with the device «AATOS-ECG» (manufactured in Finland), which transmitted data to a central monitoring station in 24-hour «on-line» monitoring center with a minimum delay (3—9 s). Results. Holter ECG monitoring was performed in 308 patients (85% of the total number of patients), the average duration of monitoring was 23 ± 1.2 hours. The quality of ECG recording was evaluated as «good» in 294 (95%) cases, as «satisfactory» in 12 (4%) cases and in 2 (1%) cases the quality of ECG recording was evaluated as «unsatisfactory». During monitoring life-threatening rhythm and conduction disorders, as well as ischemic changes in the final part of the ventricular complex, were not observed in any of the patients. Telemetric ECG monitoring was performed in 55 patients (15% of the total number included in the study). Observation was conducted with 1 lead. The study was successfully completed in 54 (98.2%) patients, in one patient (1.8%), telemetry was unsuccessfull. The quality of transmission and recording of ECG in 47 (85.5%) patients was evaluated as «good», in 7 (12.7%) as «satisfactory». During monitoring life-threatening rhythm and conduction disorders, as well as ischemic changes in the final part of the ventricular complex, were not observed in any of the patients. Conclusion. Carrying out balloon angioplasty with stenting during overnight hospitalization according to Holter and telemetric ECG monitoring is safe. The use of new modern systems of on-line remote ECG monitoring can lead to more active introduction into clinical practice of endovascular treatment in short-term hospitalization programs, but it requires further research.