
Возможности и ограничения искусственного интеллекта во флебологии: результаты систематического обзора литературы с метаанализом
Резюме
ЦЕЛЬ ИССЛЕДОВАНИЯ
Количественным образом оценить эффективность технологий на основе искусственного интеллекта (ИИ) при заболеваниях венозной системы.
МАТЕРИАЛ И МЕТОДЫ
Проведен систематический поиск литературы в базах данных PubMed, Cochrane Library и Google Scholar. В анализ включали оригинальные исследования, использовавшие ИИ-модели при венозной патологии, включая венозные тромбоэмболические осложнения (ВТЭО) и хронические заболевания вен (ХЗВ). Критериями оценки в исследованиях служили прогностическая и диагностическая эффективность, обобщенные с помощью модели случайных эффектов.
РЕЗУЛЬТАТЫ
Из оцененных 606 работ в анализ включено 100 исследований по вопросам прогнозирования (76 публикаций) и диагностики (24) ВТЭО (86) и ХЗВ (14). Для диагностических моделей ВТЭО и ХЗВ обобщенные точность, чувствительность и специфичность при внутренней валидации составили: 0,93 (95% ДИ 0,87—0,96) и 0,98 (95% ДИ 0,91—0,99); 0,89 (95% ДИ 0,81—0,96) и 0,89 (95% ДИ 0,80—0,95); 0,93 (95% ДИ 0,87—0,98) и 0,94 (95% ДИ 0,67—0,99) соответственно. Для предсказательных моделей ВТЭО обобщенные точность, чувствительность, специфичность, прецизионность и значения площади под кривой ROC (ППК) по результатам внутренней валидации составили 0,85 (95% ДИ 0,83—0,88), 0,78 (95% ДИ 0,72—0,85), 0,86 (95% ДИ 0,80—0,92), 0,60 (95% ДИ 0,45—0,74) и 0,86 (ДИ 95% 0,84—0,88) соответственно. Для предсказательных моделей ХЗВ обобщенная ППК составила 0,88 (ДИ 95% 0,82—0,95). Внешняя валидация была выполнена только в 23% случаев, а полученные метрики уступали результатам внутренней валидации.
ЗАКЛЮЧЕНИЕ
Технологии на основе ИИ демонстрируют высокую диагностическую и умеренную прогностическую эффективность при патологии венозной системы, однако требуются дальнейшие исследования с внешней валидацией для оценки внедрения в клиническую практику.
Ключевые слова
- венозные тромбоэмболические осложнения
- хронические заболевания вен
- искусственный интеллект
- прогнозирование
- диагностика
Дата поступления: 05.06.2026
Дата принятия в печать: 24.06.2026
Дата публикации: 22.09.2026
- Fukaya E, Kolluri R, Nonsurgical Management of Chronic Venous Insufficiency. N Engl J Med. 2024;391(24):2350-2359. https://doi.org/10.1056/NEJMcp2310224
- Wendelboe A, Weitz JI, Global Health Burden of Venous Thromboembolism. Arterioscler Thromb Vasc Biol. 2024;44(5):1007-1011. https://doi.org/10.1161/atvbaha.124.320151
- Камаев А.А., Булатов В.Л., Вахратьян П.Е., Волков А.М., Волков А.С., Гаврилов Е.К., Головина В.И., Ефремова О.И., Иванов О.О., Илюхин Е.А., Каторкин С.Е., Кончугова Т.В., Кравцов П.Ф., Максимов С.В., Мжаванадзе Н.Д., Пиханова Ж.М., Прядко С.И., Смирнов А.А., Сушков С.А., Чаббаров Р.Г., Шиманко А.И., Якушкин С.Н., Апханова Т.В., Деркачев С.Н., Золотухин И.А., Калинин Р.Е., Кириенко А.И., Кульчицкая Д.Б., Пелевин А.В., Петриков А.С., Рачин А.П., Селиверстов Е.И., Стойко Ю.М. Варикозное расширение вен. Флебология. 2022;16(1):41-108. https://doi.org/10.17116/flebo20221601141
- Селиверстов Е.И., Лобастов К.В., Илюхин Е.А., Апханова Т.В., Ахметзянов Р.В., Ахтямов И.Ф., Баринов В.Е., Бахметьев А.С., Белов М.В., Бобров С.А., Божкова С.А., Бредихин Р.А., Булатов В.Л., Вавилова Т.В., Варданян А.В., Воробьева Н.А., Гаврилов Е.К., Гаврилов С.Г., Головина В.И., Горин А.С., Дженина О.В., Дианов С.В., Ефремова О.И., Жуковец В.В., Замятин М.Н., Игнатьев И.А., Калинин Р.Е., Камаев А.А., Каплунов О.А., Каримова Г.Н., Карпенко А.А., Касимова А.Р., Кательницкая О.В., Кательницкий И.И., Каторкин С.Е., Князев Р.И., Кончугова Т.В., Копенкин С.С., Кошевой А.П., Кравцов П.Ф., Крылов А.Ю., Кульчицкая Д.Б., Лаберко Л.А., Лебедев И.С., Маланин Д.А., Матюшкин А.В., Мжаванадзе Н.Д., Моисеев С.В., Муштин Н.Е., Николаева М.Г., Пелевин А.В., Петриков А.С., Пирадов М.А., Пиханова Ж.М., Поддубная И.В., Порембская О.Я., Потапов М.П., Пырегов А.В., Рачин А.П., Рогачевский О.В., Рябинкина Ю.В., Сапелкин С.В., Сонькин И.Н., Сорока В.В., Сушков С.А., Счастливцев И.В., Тихилов Р.М., Трякин А.А., Фокин А.А., Хороненко В.Э., Хруслов М.В., Цатурян А.Б., Цед А.Н., Черкашин М.А., Чечулова А.В., Чуйко С.Г., Шиманко А.И., Шмаков Р.Г., Явелов И.С., Яшкин М.Н., Кириенко А.И., Золотухин И.А., Стойко Ю.М., Сучков И.А. Профилактика, диагностика и лечение тромбоза глубоких вен. Рекомендации российских экспертов. Флебология. 2023;17(3):152-296. https://doi.org/10.17116/flebo202317031152
- Perrin M, Eklof BA, Labropoulos N, Vasquez M, Nicolaides A, Blattler W, Bouhassira D, Bouskela E, Carpentier P, Darvall K, Flour M, Guex JJ, Hamel-Desnos C, Kakkos S, Launois R, Lugli M, Maleti O, Mansilha A, Rabe E, Shaydakov E. Venous symptoms: the SYM Vein Consensus statement developed under the auspices of the European Venous Forum. Int Angiol. 2016;35(4):374-398.
- Carpentier PH, Poulain C, Fabry R, Chleir F, Guias B, Bettarel-Binon C. Ascribing leg symptoms to chronic venous disorders: the construction of a diagnostic score. J Vasc Surg. 2007;46(5):991-996. https://doi.org/10.1016/j.jvs.2007.06.044
- Шадрина А.С., Золотухин И.А., Филипенко М.Л. Молекулярные механизмы развития варикозной болезни нижних конечностей. Флебология. 2017;11(2):71-75. https://doi.org/10.17116/flebo201711271-75
- Costa D, Andreucci M, Ielapi N, Serraino GF, Mastroroberto P, Bracale UM, Serra R. Molecular Determinants of Chronic Venous Disease: A Comprehensive Review. Int J Mol Sci. 2023;24(3):1928. https://doi.org/10.3390/ijms24031928
- Kahn SR, de Wit K. Pulmonary Embolism. N Engl J Med. 2022;387(1):45-57. https://doi.org/10.1056/NEJMcp2116489
- Khan F, Tritschler T, Kahn SR, Rodger MA. Venous thromboembolism. Lancet. 2021;398(10294):64-77. https://doi.org/10.1016/s0140-6736(20)32658-1
- Goodacre S, Sutton AJ, Sampson FC. Meta-analysis: The value of clinical assessment in the diagnosis of deep venous thrombosis. Ann Intern Med. 2005;143(2):129-139. https://doi.org/10.7326/0003-4819-143-2-200507190-00012
- Morrone D, Morrone V. Acute Pulmonary Embolism: Focus on the Clinical Picture. Korean Circ J. 2018;48(5):365-381. https://doi.org/10.4070/kcj.2017.0314
- Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jimenez D, Kucher N, Lang IM, Lankeit M, Lorusso R, Mazzolai L, Meneveau N, Ni Ainle F, Prandoni P, Pruszczyk P, Righini M, Torbicki A, Van Belle E, Zamorano JL, Group ESCSD. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J. 2020;41(4):543-603. https://doi.org/10.1093/eurheartj/ehz405
- Creager MA, Barnes GD, Giri J, Mukherjee D, Jones WS, Burnett AE, Carman T, Casanegra AI, Castellucci LA, Clark SM, Cushman M, de Wit K, Eaves JM, Fang MC, Goldberg JB, Henkin S, Johnston-Cox H, Kadavath S, Kadian-Dodov D, Keeling WB, Klein AJP, Li J, McDaniel MC, Moores LK, Piazza G, Prenger KS, Pugliese SC, Ranade M, Rosovsky RP, Russo F, Secemsky EA, Sista AK, Tefera L, Weinberg I, Westafer LM, Young MN. 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2026;153(12):e977-e1051. https://doi.org/10.1161/cir.0000000000001415
- De Maeseneer MG, Kakkos SK, Aherne T, Baekgaard N, Black S, Blomgren L, Giannoukas A, Gohel M, de Graaf R, Hamel-Desnos C, Jawien A, Jaworucka-Kaczorowska A, Lattimer CR, Mosti G, Noppeney T, van Rijn MJ, Stansby G, Esvs Guidelines C, Kolh P, Bastos Goncalves F, Chakfe N, Coscas R, de Borst GJ, Dias NV, Hinchliffe RJ, Koncar IB, Lindholt JS, Trimarchi S, Tulamo R, Twine CP, Vermassen F, Wanhainen A, Document R, Bjorck M, Labropoulos N, Lurie F, Mansilha A, Nyamekye IK, Ramirez Ortega M, Ulloa JH, Urbanek T, van Rij AM, Vuylsteke ME. Editor’s Choice ‒ European Society for Vascular Surgery (ESVS) 2022 Clinical Practice Guidelines on the Management of Chronic Venous Disease of the Lower Limbs. Eur J Vasc Endovasc Surg. 2022;63(2):184-267. https://doi.org/10.1016/j.ejvs.2021.12.024
- Goodacre S, Sampson F, Thomas S, van Beek E, Sutton A. Systematic review and meta-analysis of the diagnostic accuracy of ultrasonography for deep vein thrombosis. BMC Med Imaging. 2005;5:6. https://doi.org/10.1186/1471-2342-5-6
- Patel P, Patel P, Bhatt M, Braun C, Begum H, Wiercioch W, Varghese J, Wooldridge D, Alturkmani H, Thomas M, Baig M, Bahaj W, Khatib R, Kehar R, Ponnapureddy R, Sethi A, Mustafa A, Lim W, Le Gal G, Bates SM, Haramati LB, Kline J, Lang E, Righini M, Kalot MA, Husainat NM, Jabiri YNA, Schünemann HJ, Mustafa RA. Systematic review and meta-analysis of test accuracy for the diagnosis of suspected pulmonary embolism. Blood Adv. 2020;4(18):4296-4311. https://doi.org/10.1182/bloodadvances.2019001052
- Pandor A, Tonkins M, Goodacre S, Sworn K, Clowes M, Griffin XL, Holland M, Hunt BJ, de Wit K, Horner D. Risk assessment models for venous thromboembolism in hospitalised adult patients: a systematic review. BMJ Open. 2021;11(7):e045672. https://doi.org/10.1136/bmjopen-2020-045672
- Gerotziafas GT, Mahé I, Lefkou E, AboElnazar E, Abdel-Razeq H, Taher A, Antic D, Elalamy I, Syrigos K, Van Dreden P. Overview of risk assessment models for venous thromboembolism in ambulatory patients with cancer. Thromb Res. 2020;191(Suppl 1):S50-s57. https://doi.org/10.1016/s0049-3848(20)30397-2
- Gu Y, Yang Y, Gao X, Wang Y, Yang L, Wei Y. Application of artificial intelligence in risk assessment and management of venous thromboembolism: scoping review. Front Physiol. 2025;16:1664470. https://doi.org/10.3389/fphys.2025.1664470
- Moumneh T, Riou J, Douillet D, Henni S, Mottier D, Tritschler T, Le Gal G, Roy PM. Validation of risk assessment models predicting venous thromboembolism in acutely ill medical inpatients: A cohort study. J Thromb Haemost. 2020;18(6):1398-1407. https://doi.org/10.1111/jth.14796
- Al-Dorzi HM, Arishi H, Al-Hameed FM, Burns KEA, Mehta S, Jose J, Alsolamy SJ, Abdukahil SAI, Afesh LY, Alshahrani MS, Mandourah Y, Almekhlafi GA, Almaani M, Al Bshabshe A, Finfer S, Arshad Z, Khalid I, Mehta Y, Gaur A, Hawa H, Buscher H, Lababidi H, Al Aithan A, Al-Dawood A, Arabi YM. Performance of Risk Assessment Models for VTE in Patients Who Are Critically Ill Receiving Pharmacologic Thromboprophylaxis: A Post Hoc Analysis of the Pneumatic Compression for Preventing VTE Trial. Chest. 2025;167(2):598-610. https://doi.org/10.1016/j.chest.2024.07.182
- Häfliger E, Kopp B, Darbellay Farhoumand P, Choffat D, Rossel JB, Reny JL, Aujesky D, Méan M, Baumgartner C. Risk Assessment Models for Venous Thromboembolism in Medical Inpatients. JAMA Netw Open. 2024;7(5):e249980. https://doi.org/10.1001/jamanetworkopen.2024.9980
- Haug CJ, Drazen JM. Artificial Intelligence and Machine Learning in Clinical Medicine, 2023. N Engl J Med. 2023;388(13):1201-1208. https://doi.org/10.1056/NEJMra2302038
- Howell MD, Corrado GS, DeSalvo KB. Three Epochs of Artificial Intelligence in Health Care. Jama. 2024;331(3):242-244. https://doi.org/10.1001/jama.2023.25057
- Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Bmj. 2021;372:n71. https://doi.org/10.1136/bmj.n71
- Moons KGM, Damen JAA, Kaul T, Hooft L, Andaur Navarro C, Dhiman P, Beam AL, Van Calster B, Celi LA, Denaxas S, Denniston AK, Ghassemi M, Heinze G, Kengne AP, Maier-Hein L, Liu X, Logullo P, McCradden MD, Liu N, Oakden-Rayner L, Singh K, Ting DS, Wynants L, Yang B, Reitsma JB, Riley RD, Collins GS, van Smeden M. PROBAST+AI: an updated quality, risk of bias, and applicability assessment tool for prediction models using regression or artificial intelligence methods. Bmj. 2025;388:e082505. https://doi.org/10.1136/bmj-2024-082505
- Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, Leeflang MM, Sterne JA, Bossuyt PM. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011;155(8):529-536. https://doi.org/10.7326/0003-4819-155-8-201110180-00009
- Yang Y, Wang X, Huang Y, Chen N, Shi J, Chen T. Ontology-based venous thromboembolism risk assessment model developing from medical records. BMC Med Inform Decis Mak. 2019;19(Suppl 4):151. https://doi.org/10.1186/s12911-019-0856-2
- Sabra S, Mahmood Malik K, Alobaidi M. Prediction of venous thromboembolism using semantic and sentiment analyses of clinical narratives. Comput Biol Med. 2018;94:1-10. https://doi.org/10.1016/j.compbiomed.2017.12.026
- Ferroni P, Zanzotto FM, Scarpato N, Riondino S, Nanni U, Roselli M, Guadagni F. Risk Assessment for Venous Thromboembolism in Chemotherapy-Treated Ambulatory Cancer Patients. Med Decis Making. 2017;37(2): 234-242. https://doi.org/10.1177/0272989x16662654
- Ferroni P, Zanzotto FM, Scarpato N, Riondino S, Guadagni F, Roselli M. Validation of a Machine Learning Approach for Venous Thromboembolism Risk Prediction in Oncology. Dis Markers. 2017;2017:8781379. https://doi.org/10.1155/2017/8781379
- Xue B, Li D, Lu C, King CR, Wildes T, Avidan MS, Kannampallil T, Abraham J. Use of Machine Learning to Develop and Evaluate Models Using Preoperative and Intraoperative Data to Identify Risks of Postoperative Complications. JAMA Netw Open. 2021;4(3):e212240. https://doi.org/10.1001/jamanetworkopen.2021.2240
- Martins TD, Annichino-Bizzacchi JM, Romano AVC, Maciel Filho R. Artificial neural networks for prediction of recurrent venous thromboembolism. Int J Med Inform. 2020;141:104221. https://doi.org/10.1016/j.ijmedinf.2020.104221
- Ding R, Ding Y, Zheng D, Huang X, Dai J, Jia H, Deng M, Yuan H, Zhang Y, Fu H. Machine Learning-Based Screening of Risk Factors and Prediction of Deep Vein Thrombosis and Pulmonary Embolism After Hip Arthroplasty. Clin Appl Thromb Hemost. 2023;29:10760296231186145. https://doi.org/10.1177/10760296231186145
- Tabari A, Ma Y, Alfonso J, Gebran A, Kaafarani H, Bertsimas D, Daye D. An artificial intelligence interpretable tool to predict risk of deep vein thrombosis after endovenous thermal ablation. J Vasc Surg Venous Lymphat Disord. 2025;13(5):102253. https://doi.org/10.1016/j.jvsv.2025.102253
- Meng L, Wei T, Fan R, Su H, Liu J, Wang L, Huang X, Qi Y, Li X. Development and validation of a machine learning model to predict venous thromboembolism among hospitalized cancer patients. Asia Pac J Oncol Nurs. 2022;9(12):100128. https://doi.org/10.1016/j.apjon.2022.100128
- Jin S, Qin D, Liang BS, Zhang LC, Wei XX, Wang YJ, Zhuang B, Zhang T, Yang ZP, Cao YW, Jin SL, Yang P, Jiang B, Rao BQ, Shi HP, Lu Q. Machine learning predicts cancer-associated deep vein thrombosis using clinically available variables. Int J Med Inform. 2022;161:104733. https://doi.org/10.1016/j.ijmedinf.2022.104733
- Lei H, Zhang M, Wu Z, Liu C, Li X, Zhou W, Long B, Ma J, Zhang H, Wang Y, Wang G, Gong M, Hong N, Liu H, Wu Y. Development and Validation of a Risk Prediction Model for Venous Thromboembolism in Lung Cancer Patients Using Machine Learning. Front Cardiovasc Med. 2022;9:845210. https://doi.org/10.3389/fcvm.2022.845210
- Qin L, Liang Z, Xie J, Ye G, Guan P, Huang Y, Li X. Development and validation of machine learning models for postoperative venous thromboembolism prediction in colorectal cancer inpatients: a retrospective study. J Gastrointest Oncol. 2023;14(1):220-232. https://doi.org/10.21037/jgo-23-18
- Li B, Eisenberg N, Beaton D, Lee DS, Al-Omran L, Wijeysundera DN, Hussain MA, Rotstein OD, de Mestral C, Mamdani M, Roche-Nagle G, Al-Omran M. Predicting inferior vena cava filter complications using machine learning. J Vasc Surg Venous Lymphat Disord. 2024;12(6):101943. https://doi.org/10.1016/j.jvsv.2024.101943
- Zeng Y, Chen Y, Zhu D, Xu J, Zhang X, Ying H, Song X, Zhou R, Wang Y, Yu F. Machine learning assisted radiomics in predicting postoperative occurrence of deep venous thrombosis in patients with gastric cancer. BMC Cancer. 2025;25(1):220. https://doi.org/10.1186/s12885-025-13630-1
- Chen Y, Jiang Y. Construction of Prediction Model of Deep Vein Thrombosis Risk after Total Knee Arthroplasty Based on XGBoost Algorithm. Comput Math Methods Med. 2022;2022:3452348. https://doi.org/10.1155/2022/3452348
- Qiu W, Cui P, Li S, Tang Z, Chen J, Wang J, Li Y. Machine learning models predict risk of lower extremity deep vein thrombosis in hospitalized patients with spontaneous intracerebral hemorrhage. Sci Rep. 2025;15(1):24932. https://doi.org/10.1038/s41598-025-10905-2
- Ryan L, Mataraso S, Siefkas A, Pellegrini E, Barnes G, Green-Saxena A, Hoffman J, Calvert J, Das R. A Machine Learning Approach to Predict Deep Venous Thrombosis Among Hospitalized Patients. Clin Appl Thromb Hemost. 2021;27:1076029621991185. https://doi.org/10.1177/1076029621991185
- Yan YD, Yu Z, Ding LP, Zhou M, Zhang C, Pan MM, Zhang JY, Wang ZY, Gao F, Li HY, Zhang GY, Lin HW, Wang MG, Gu ZC, Machine Learning to Dynamically Predict In-Hospital Venous Thromboembolism After Inguinal Hernia Surgery: Results From the CHAT-1 Study. Clin Appl Thromb Hemost. 2023;29:10760296231171082. https://doi.org/10.1177/10760296231171082
- Li L, Wu L, Wang Y, Wang H, Zheng X, Han L, Yin Q, Wu X, Bian Y. Development of a venous thromboembolism risk prediction model for patients with primary membranous nephropathy based on machine learning. Front Pharmacol. 2025;16:1683708. https://doi.org/10.3389/fphar.2025.1683708
- Chen C, Hu Z, Xu Q, Yuan L, Yuan Y, Zheng X, Lei H. Development and validation of machine learning models for assessing the risk of postoperative venous thromboembolism in cervical cancer patients. Sci Rep. 2025;Nov 27;15:45561. https://doi.org/10.1038/s41598-025-29761-1
- Jiang F, Ye C, Yu D, Chen F, Xu W, He P, Zhang C, Tong M, Bao X. Predicting lower extremity deep venous thrombosis in patients with aneurysmal subarachnoid hemorrhage: a machine learning study. Front Neurol. 2025;16:1659212. https://doi.org/10.3389/fneur.2025.1659212
- Zhang Y, Ma Y, Wang J, Guan Q, Yu B. Construction and validation of a clinical prediction model for deep vein thrombosis in patients with digestive system tumors based on a machine learning. Am J Cancer Res. 2024;14(1):155-168. https://doi.org/10.62347/lndl8700
- Chen X, Hou M, Wang D. Machine learning-based model for prediction of deep vein thrombosis after gynecological laparoscopy: A retrospective cohort study. Medicine (Baltimore). 2024;103(1):e36717. https://doi.org/10.1097/md.0000000000036717
- Rasouli Dezfouli E, Delen D, Zhao H, Davazdahemami B. A Machine Learning Framework for Assessing the Risk of Venous Thromboembolism in Patients Undergoing Hip or Knee Replacement. J Healthc Inform Res. 2022;6(4):423-441. https://doi.org/10.1007/s41666-022-00121-2
- An T, Han H, Xie J, Wang Y, Zhao Y, Jia H, Wang Y. Enhancing prediction and stratifying risk: machine learning and bayesian-learning models for catheter-related thrombosis in chemotherapy patients. BMC Cancer. 2025;25(1):552. https://doi.org/10.1186/s12885-025-13946-y
- Jiang T, Yang Z, Tang X, Fan N, Hu Z, Li J, Liu T, Peng Y, Chen S, Guo B, Zhang X, Chen Y, Li J, Huang D, Liu J, Zhang Y, Liu X, Wei X, Liu Z, Lei H, Liu Y. Development and validation of a machine learning-based early warning system for predicting venous thromboembolism risk in hospitalized lymphoma patients undergoing chemotherapy: a multicenter and retrospective cohort study. Front Oncol. 2025;15:1566905. https://doi.org/10.3389/fonc.2025.1566905
- Xu Q, Lei H, Li X, Li F, Shi H, Wang G, Sun A, Wang Y, Peng B. Machine learning predicts cancer-associated venous thromboembolism using clinically available variables in gastric cancer patients. Heliyon. 2023;9(1):e12681. https://doi.org/10.1016/j.heliyon.2022.e12681
- Tian Y, Liu J, Wu S, Zheng Y, Han R, Bao Q, Li L, Yang T. Development and validation of a deep learning-enhanced prediction model for the likelihood of pulmonary embolism. Front Med (Lausanne). 2025;12:1506363. https://doi.org/10.3389/fmed.2025.1506363
- Sheng W, Wang X, Xu W, Hao Z, Ma H, Zhang S. Development and validation of machine learning models for venous thromboembolism risk assessment at admission: a retrospective study. Front Cardiovasc Med. 2023;10:1198526. https://doi.org/10.3389/fcvm.2023.1198526
- Liu Y, Song C, Tian Z, Shen W. Ten-Year Multicenter Retrospective Study Utilizing Machine Learning Algorithms to Identify Patients at High Risk of Venous Thromboembolism After Radical Gastrectomy. Int J Gen Med. 2023;16:1909-1925. https://doi.org/10.2147/ijgm.S408770
- Zhao L, Yao L. A Predictive Model Based on Machine Learning Algorithm for Vein Thrombosis After Ovarian Cancer Resection. Int J Womens Health. 2025;17:4207-4226. https://doi.org/10.2147/ijwh.S550882
- Cheng Q, Liu Y, Zhu P, Cai W, Shi L. Predicting Preoperative Deep Vein Thrombosis in Elderly Hip Fracture Patients Using an Interpretable Machine Learning Model. Int J Gen Med. 2025;18:7271-7282. https://doi.org/10.2147/ijgm.S551225
- Zhang B, Qin Y, Jiu L, Qin C, Wang J, Zhao H. A study on the risk prediction model for venous thromboembolism in orthopedic inpatients based on machine learning. Front Med (Lausanne). 2025;12:1574546. https://doi.org/10.3389/fmed.2025.1574546
- Huang Y, Liang H, Huang S, Xie X, Deng B, Liang W. Evaluation of risk factors for thromboembolic events in multiple myeloma patients using multiple machine learning models. Medicine (Baltimore). 2025;104(7):e41428. https://doi.org/10.1097/md.0000000000041428
- Townsley SK, Basu D, Vora J, Wun T, Chuah CN, Shankar PRV. Predicting venous thromboembolism (VTE) risk in cancer patients using machine learning. Health Care Sci. 2023;2(4):205-222. https://doi.org/10.1002/hcs2.55
- Park JI, Kim D, Lee JA, Zheng K, Amin A. Personalized Risk Prediction for 30-Day Readmissions With Venous Thromboembolism Using Machine Learning. J Nurs Scholarsh. 2021;53(3):278-287. https://doi.org/10.1111/jnu.12637
- Lu C, Song J, Li H, Yu W, Hao Y, Xu K, Xu P. Predicting Venous Thrombosis in Osteoarthritis Using a Machine Learning Algorithm: A Population-Based Cohort Study. J Pers Med. 2022;12(1):114. https://doi.org/10.3390/jpm12010114
- Shohat N, Ludwick L, Sherman MB, Fillingham Y, Parvizi J. Using machine learning to predict venous thromboembolism and major bleeding events following total joint arthroplasty. Sci Rep. 2023;13(1):2197. https://doi.org/10.1038/s41598-022-26032-1
- Su J, Tang Y, Wang Y, Chen C, Song B. Predicting deep vein thrombosis using machine learning and blood routine analysis. Front Big Data. 2025;8:1605258. https://doi.org/10.3389/fdata.2025.1605258
- Ju J, Chen J, Wang J, Yang L. Predicting the Risk of Deep Venous Thrombosis in Elderly Patients: A Comparative Analysis of Seven Machine Learning Models. Clin Appl Thromb Hemost. 2025;31:10760296251375842. https://doi.org/10.1177/10760296251375842
- Hou T, Qiao W, Song S, Guan Y, Zhu C, Yang Q, Gu Q, Sun L, Liu S. The Use of Machine Learning Techniques to Predict Deep Vein Thrombosis in Rehabilitation Inpatients. Clin Appl Thromb Hemost. 2023;29: 10760296231179438. https://doi.org/10.1177/10760296231179438
- Zheng X, Wu L, Li L, Wang Y, Yin Q, Han L, Wu X, Bian Y. Development and validation of a prediction model for VTE risk in gastric and esophageal cancer patients. Front Pharmacol. 2025;16:1448879. https://doi.org/10.3389/fphar.2025.1448879
- Jiang Y, Li A, Li Z, Li Y, Li R, Zhao Q, Li G. Leveraging machine learning for enhanced and interpretable risk prediction of venous thromboembolism in acute ischemic stroke care. PLoS One. 2025;20(3):e0302676. https://doi.org/10.1371/journal.pone.0302676
- Zhang Z, Xu S, Song M, Huang W, Yan M, Li X. Machine learning-based prediction model and web calculator for postoperative LDVT in colorectal cancer. Front Oncol. 2025;15:1673705. https://doi.org/10.3389/fonc.2025.1673705
- Nafee T, Gibson CM, Travis R, Yee MK, Kerneis M, Chi G, AlKhalfan F, Hernandez AF, Hull RD, Cohen AT, Harrington RA, Goldhaber SZ. Machine learning to predict venous thrombosis in acutely ill medical patients. Res Pract Thromb Haemost. 2020;4(2):230-237. https://doi.org/10.1002/rth2.12292
- Baki H, Özçelik İB. Machine Learning-Based Prediction of Postoperative Deep Vein Thrombosis Following Tibial Fracture Surgery. Diagnostics (Basel). 2025;15(14):1787. https://doi.org/10.3390/diagnostics15141787
- Wei C, Wang J, Yu P, Li A, Xiong Z, Yuan Z, Yu L, Luo J. Comparison of different machine learning classification models for predicting deep vein thrombosis in lower extremity fractures. Sci Rep. 2024;14(1):6901. https://doi.org/10.1038/s41598-024-57711-w
- Jin J, Lu J, Su X, Xiong Y, Ma S, Kong Y, Xu H. Development and Validation of an ICU-Venous Thromboembolism Prediction Model Using Machine Learning Approaches: A Multicenter Study. Int J Gen Med. 2024;17: 3279-3292. https://doi.org/10.2147/ijgm.S467374
- Liu H, Yuan H, Wang Y, Huang W, Xue H, Zhang X. Prediction of venous thromboembolism with machine learning techniques in young-middle-aged inpatients. Sci Rep. 2021;11(1):12868. https://doi.org/10.1038/s41598-021-92287-9
- Chen R, Petrazzini BO, Malick WA, Rosenson RS, Do R. Prediction of Venous Thromboembolism in Diverse Populations Using Machine Learning and Structured Electronic Health Records. Arterioscler Thromb Vasc Biol. 2024;44(2):491-504. https://doi.org/10.1161/atvbaha.123.320331
- Hopkins BS, Cloney MB, Dhillon ES, Texakalidis P, Dallas J, Nguyen VN, Ordon M, Tecle NE, Chen TC, Hsieh PC, Liu JC, Koski TR, Dahdaleh NS. Using machine learning and big data for the prediction of venous thromboembolic events after spine surgery: A single-center retrospective analysis of multiple models on a cohort of 6869 patients. J Craniovertebr Junction Spine. 2023;14(3):221-229. https://doi.org/10.4103/jcvjs.jcvjs_69_23
- Chen Z, Qiang M, Hong Y, Tian W, Tang M, Liu W. Machine learning-based preoperative prediction of perioperative venous thromboembolism in Chinese lung cancer patients: a retrospective cohort study. Front Oncol. 2025;15:1588817. https://doi.org/10.3389/fonc.2025.1588817
- Hu Z, Xu Q, Yuan Y, Li X, Zhang H, Wang Z, Lei H, Wu Y. Development and validation of an explainable machine learning model for predicting postoperative venous thromboembolism in esophageal cancer. Int J Surg. 2025;112(1):1363-1372 https://doi.org/10.1097/js9.0000000000003562
- Yang SZ, Peng MH, Lin Q, Guan SW, Zhang KL, Yu HB. A machine learning-based predictive model for the occurrence of lower extremity deep vein thrombosis after laparoscopic surgery in abdominal surgery. Front Surg. 2025;12:1502944. https://doi.org/10.3389/fsurg.2025.1502944
- Huang L, Gong L, Chen J, Chen X, Yao B, Wang Z, Weng S. Machine learning-based risk prediction of postoperative deep vein thrombosis in Chinese patients undergoing gastrointestinal surgery. Front Cardiovasc Med. 2025;12:1630099. https://doi.org/10.3389/fcvm.2025.1630099
- You H, Zhao J, Zhang M, Jin Z, Feng X, Tan W, Wu L, Duan X, Luo H, Zhao C, Zhan F, Wu Z, Li H, Yang M, Xu J, Wei W, Wang Y, Shi J, Qu J, Wang Q, Leng X, Tian X, Zhao Y, Li M, Zeng X. Development and external validation of a prediction model for venous thromboembolism in systemic lupus erythematosus. RMD Open. 2023;9(4):e003568. https://doi.org/10.1136/rmdopen-2023-003568
- Qiao N, Zhang Q, Chen L, He W, Ma Z, Ye Z, He M, Zhang Z, Zhou X, Shen M, Shou X, Cao X, Wang Y, Zhao Y. Machine learning prediction of venous thromboembolism after surgeries of major sellar region tumors. Thromb Res. 2023;226:1-8. https://doi.org/10.1016/j.thromres.2023.04.007
- Yang J, He J, Zhang H. Automating venous thromboembolism risk assessment: a dual-branch deep learning method using electronic medical records. Front Med (Lausanne). 2023;10:1237616. https://doi.org/10.3389/fmed.2023.1237616
- Yan YD, Wu XW, Li Y, Lin HW, Zhang ZT, Jia D, Yao HW, Gu ZC. Machine learning to predict venous thromboembolism After Colorectal Cancer Surgery: a Chinese dynamic modelling study. Int J Surg. 2025112(3):6718-6728. https://doi.org/10.1097/js9.0000000000004036
- Nassour N, Akhbari B, Ranganathan N, Shin D, Ghaednia H, Ashkani-Esfahani S, DiGiovanni CW, Guss D. Using machine learning in the prediction of symptomatic venous thromboembolism following ankle fracture. Foot Ankle Surg. 2024;30(2):110-116. https://doi.org/10.1016/j.fas.2023.10.003
- Liu S, Zhang F, Xie L, Wang Y, Xiang Q, Yue Z, Feng Y, Yang Y, Li J, Luo L, Yu C. Machine learning approaches for risk assessment of peripherally inserted Central catheter-related vein thrombosis in hospitalized patients with cancer. Int J Med Inform. 2019;129:175-183. https://doi.org/10.1016/j.ijmedinf.2019.06.001
- Qi H, Li L, Fang J, Pei T, Li A, Ding Z, Chen T. Development and Validation of an Interpretable Machine Learning Model for Predicting venous Thromboembolism in ICU patients With Traumatic Brain Injury: A Multicenter Study. World Neurosurg. 2025;202:124399. https://doi.org/10.1016/j.wneu.2025.124399
- Hu Z, Li X, Yuan Y, Xu Q, Zhang W, Lei H. Development and validation of machine learning models for predicting venous thromboembolism in colorectal cancer patients: A cohort study in China. Int J Med Inform. 2025;195:105770. https://doi.org/10.1016/j.ijmedinf.2024.105770
- Yuan C, Luo R, Li J, Fan Y, Jing J. Development of a machine learning-based predictive model for venous thromboembolism risk assessment in orthopaedic patients with routine prophylaxis. Br J Haematol. 2025;207(3):1047-1057. https://doi.org/10.1111/bjh.20265
- Muñoz AJ, Souto JC, Lecumberri R, Obispo B, Sanchez A, Aparicio J, Aguayo C, Gutierrez D, Palomo AG, Fanjul V, Del Rio-Bermudez C, Viñuela-Benéitez MC, Hernández-Presa M. Development of a predictive model of venous thromboembolism recurrence in anticoagulated cancer patients using machine learning. Thromb Res. 2023;228:181-188. https://doi.org/10.1016/j.thromres.2023.06.015
- Ma H, Sheng W, Li J, Hou L, Yang J, Cai J, Xu W, Zhang S. A novel hierarchical machine learning model for hospital-acquired venous thromboembolism risk assessment among multiple-departments. J Biomed Inform. 2021;122:103892. https://doi.org/10.1016/j.jbi.2021.103892
- Li Y, Tian R, Liu K, Wu F, Feng T, Liu Y, You C, Guo R. Prediction of venous thromboembolism after spontaneous intracerebral hemorrhage based on machine learning. Clin Neurol Neurosurg. 2025;258:109159. https://doi.org/10.1016/j.clineuro.2025.109159
- Hu H, Wu Z, Zhao J. Peripherally inserted central-related upper extremity deep vein thrombosis and machine learning. Vascular. 2024;32(6):1346-1351. https://doi.org/10.1177/17085381241236543
- Huang Z, Buddhiraju A, Chen TL, RezazadehSaatlou M, Chen SF, Bacevich BM, Xiao P, Kwon YM. Machine learning models based on a national-scale cohort accurately identify patients at high risk of deep vein thrombosis following primary total hip arthroplasty. Orthop Traumatol Surg Res. 2025;111(4):104238. https://doi.org/10.1016/j.otsr.2025.104238
- Lin B, Chen F, Wu M, Li C, Lin L. Machine learning models for prediction of postoperative venous thromboembolism in gynecological malignant tumor patients. J Obstet Gynaecol Res. 2024;50(7):1175-1181. https://doi.org/10.1111/jog.15960
- Fresard ME, Erices R, Bravo ML, Cuello M, Owen GI, Ibanez C, Rodriguez-Fernandez M. Multi-Objective Optimization for Personalized Prediction of Venous Thromboembolism in Ovarian Cancer Patients. IEEE J Biomed Health Inform. 2020;24(5):1500-1508. https://doi.org/10.1109/jbhi.2019.29434992
- Li B, Eisenberg N, Beaton D, Lee DS, Al-Omran L, Wijeysundera DN, Hussain MA, Rotstein OD, de Mestral C, Mamdani M, Roche-Nagle G, Al-Omran M. Predicting lack of clinical improvement following varicose vein ablation using machine learning. J Vasc Surg Venous Lymphat Disord. 2025;13(3):102162. https://doi.org/10.1016/j.jvsv.2024.102162
- Ngo QC, Ogrin R, Kumar DK. Computerised prediction of healing for venous leg ulcers. Scientific Reports. 2022;12(1):17962. https://doi.org/10.1038/s41598-022-20835-y
- Li S, Liu Y, Liu M, Wang L, Li X. Comprehensive bioinformatics analysis reveals biomarkers of DNA methylation-related genes in varicose veins. Front Genet. 2022;13:1013803. https://doi.org/10.3389/fgene.2022.1013803
- Yu T, Shen R, You G, Lv L, Kang S, Wang X, Xu J, Zhu D, Xia Z, Zheng J, Huang K. Machine learning-based prediction of the post-thrombotic syndrome: Model development and validation study. Front Cardiovasc Med. 2022;9:990788. https://doi.org/10.3389/fcvm.2022.990788
- Wu Z, Li Y, Lei J, Qiu P, Liu H, Yang X, Chen T, Lu X. Developing and optimizing a machine learning predictive model for post-thrombotic syndrome in a longitudinal cohort of patients with proximal deep venous thrombosis. J Vasc Surg Venous Lymphat Disord. 2023;11(3):555-564.e5. https://doi.org/10.1016/j.jvsv.2022.12.006
- Shi Q, Chen W, Pan Y, Yin S, Fu Y, Mei J, Xue Z. An Automatic Classification Method on Chronic Venous Insufficiency Images. Sci Rep. 2018; 8(1):17952. https://doi.org/10.1038/s41598-018-36284-5
- Barulina M, Sanbaev A, Okunkov S, Ulitin I, Okoneshnikov I. Deep Learning Approaches to Automatic Chronic Venous Disease Classification. Mathematics. 2022;10(19):3571.
- Золотухин И.А., Квасников Б.Б., Линник О.Ж., Шияхметов С.Б., Бутова К.Г. Точность приложения на основе искусственного интеллекта при выявлении хронических заболеваний вен классов C1 и C2. Флебология. 2024;18(2):132-138. https://doi.org/10.17116/flebo202418021132
- Nauman R, Saiyed VGP. Enhance Varicose Vein Detection with Deep Neural Network. International Journal on Science and Technology. 2025;16(2):1-18. https://doi.org/10.71097/IJSAT.v16.i2.5244
- Rajathi V, Bhavani R, Wiselin Jiji G. Varicose ulcer (C6) wound image tissue classification using multidimensional convolutional neural networks. The Imaging Science Journal. 2019;67(7):374-384. https://doi.org/10.1080/13682199.2019.1663083
- Thanka MR, Edwin EB, Joy RP, Priya SJ, Ebenezer V. Varicose veins chronic venous diseases image classification using multidimensional convolutional neural networks. in 2022 6th International Conference on Devices, Circuits and Systems (ICDCS). 2022;364-368. IEEE https://doi.org/10.1109/ICDCS54290
- Krishnan N, Muthu P. Detection of chronic venous insufficiency condition using transfer learning with convolutional neural networks based on thermal images. Biomedical Engineering: Applications, Basis and Communications. 2024;36(01):2350030. https://doi.org/10.4015/S1016237223500345
- Levshinskii V, Galazis C, Losev A, Zamechnik T, Kharybina T, Vesnin S, Goryanin I. Using AI and passive medical radiometry for diagnostics (MWR) of venous diseases. Comput Methods Programs Biomed. 2022;215:106611. https://doi.org/10.1016/j.cmpb.2021.106611
- Kainz B, Heinrich MP, Makropoulos A, Oppenheimer J, Mandegaran R, Sankar S, Deane C, Mischkewitz S, Al-Noor F, Rawdin AC, Ruttloff A, Stevenson MD, Klein-Weigel P, Curry N. Non-invasive diagnosis of deep vein thrombosis from ultrasound imaging with machine learning. NPJ Digit Med. 2021;4(1):137. https://doi.org/10.1038/s41746-021-00503-7
- Seo JW, Park S, Kim YJ, Hwang JH, Yu SH, Kim JH, Kim KG. Artificial intelligence-based iliofemoral deep venous thrombosis detection using a clinical approach. Sci Rep. 2023;13(1):967. https://doi.org/10.1038/s41598-022-25849-0
- Huang C, Tian J, Yuan C, Zeng P, He X, Chen H, Huang Y, Huang B. Fully Automated Segmentation of Lower Extremity Deep Vein Thrombosis Using Convolutional Neural Network. Biomed Res Int. 2019;2019:3401683. https://doi.org/10.1155/2019/3401683
- Huang SC, Kothari T, Banerjee I, Chute C, Ball RL, Borus N, Huang A, Patel BN, Rajpurkar P, Irvin J, Dunnmon J, Bledsoe J, Shpanskaya K, Dhaliwal A, Zamanian R, Ng AY, Lungren MP. PENet-a scalable deep-learning model for automated diagnosis of pulmonary embolism using volumetric CT imaging. NPJ Digit Med. 2020;3:61. https://doi.org/10.1038/s41746-020-0266-y
- Weikert T, Winkel DJ, Bremerich J, Stieltjes B, Parmar V, Sauter AW, Sommer G. Automated detection of pulmonary embolism in CT pulmonary angiograms using an AI-powered algorithm. Eur Radiol. 2020;30(12):6545-6553. https://doi.org/10.1007/s00330-020-06998-0
- Huhtanen H, Nyman M, Mohsen T, Virkki A, Karlsson A, Hirvonen J. Automated detection of pulmonary embolism from CT-angiograms using deep learning. BMC Medical Imaging. 2022;22(1):43. https://doi.org/10.1186/s12880-022-00763-z
- Oppenheimer J, Mandegaran R, Staabs F, Adler A, Singohl S, Kainz B, Heinrich M, Geroulakos G, Spiliopoulos S, Avgerinos E. Remote Expert DVT Triaging of Novice-User Compression Sonography with AI-Guidance. Ann Vasc Surg. 2024;99:272-279. https://doi.org/10.1016/j.avsg.2023.08.022
- Avgerinos E, Spiliopoulos S, Psachoulia F, Yfantis A, Plakas G, Grigoriadis S, Speranza G, Kakisis Y. Novel Artificial Intelligence Guided Non-expert Compression Ultrasound Deep Vein Thrombosis Diagnostic Pathway May Reduce Vascular Laboratory Venous Testing. Eur J Vasc Endovasc Surg. 2025;70(4):517-522. https://doi.org/10.1016/j.ejvs.2025.04.070
- Sun C, Xiong X, Zhang T, Guan X, Mao H, Yang J, Zhang X, Sun Y, Chen H, Xie G. Deep Learning for Accurate Segmentation of Venous Thrombus from Black-Blood Magnetic Resonance Images: A Multicenter Study. Biomed Res Int. 2021;2021:4989297. https://doi.org/10.1155/2021/4989297
- Pavihaa LB, Vidhya S. Innovative modified-net architecture: enhanced segmentation of deep vein thrombosis. Sci Rep. 2024;14(1):30835. https://doi.org/10.1038/s41598-024-81703-5
- Yan B, Guo H, Hu T, Zhang Y, Zheng Z, Du W, Gu Y. Development and validation of deep vein thrombosis diagnostic model based on machine learning methods. Ann Hematol. 2025;104(10):5441-5451. https://doi.org/10.1007/s00277-025-06628-z
- Chen PW, Tseng BY, Yang ZH, Yu CH, Lin KT, Chen JN, Liu PY. Deep learning model for diagnosis of venous thrombosis from lower extremity peripheral ultrasound imaging. iScience. 2024;27(12):111318. https://doi.org/10.1016/j.isci.2024.111318
- Cao J, An GS, Li RQ, Hou ZJ, Li J, Jin QQ, Du QX, Sun JH. Novel Strategy for Human Deep Vein Thrombosis Diagnosis Based on Metabolomics and Stacking Machine Learning. Anal Chem. 2024;96(36):14560-14570. https://doi.org/10.1021/acs.analchem.4c02973
- Villacorta H, Pickering JW, Horiuchi Y, Olim M, Coyne C, Maisel AS, Than MP. Machine learning with D-dimer in the risk stratification for pulmonary embolism: a derivation and internal validation study. Eur Heart J Acute Cardiovasc Care. 2022;11(1):13-19. https://doi.org/10.1093/ehjacc/zuab089
- Agharezaei L, Agharezaei Z, Nemati A, Bahaadinbeigy K, Keynia F, Baneshi MR, Iranpour A, Agharezaei M. The Prediction of the Risk Level of Pulmonary Embolism and Deep Vein Thrombosis through Artificial Neural Network. Acta Inform Med. 2016;24(5):354-359. https://doi.org/10.5455/aim.2016.24.354.359
- Denisov V, Chistogov M, Averin D, Zabelinskaya D, Bobrov I, Kondratiuk N, Gasnikov A, Galchenko M, Lobastov K, Borsuk D. Development and validation of the «IVENUS» artificial intelligence model for automated CEAP classification of early-stage chronic venous disease using lower-limb photographs. J Vasc Surg Venous Lymphat Disord. 2026 Jul;14(4):102503. https://doi.org/10.1016/j.jvsv.2026.102503
- Avanzo M, Stancanello J, Pirrone G, Drigo A, Retico A. The Evolution of Artificial Intelligence in Medical Imaging: From Computer Science to Machine and Deep Learning. Cancers (Basel). 2024;16(21):3702. https://doi.org/10.3390/cancers16213702
- van Es N, Ventresca M, Di Nisio M, Zhou Q, Noble S, Crowther M, Briel M, Garcia D, Lyman GH, Macbeth F, Griffiths G, Iorio A, Mbuagbaw L, Neumann I, Brozek J, Guyatt G, Streiff MB, Baldeh T, Florez ID, Gurunlu Alma O, Agnelli G, Ageno W, Marcucci M, Bozas G, Zulian G, Maraveyas A, Lebeau B, Lecumberri R, Sideras K, Loprinzi C, McBane R, Pelzer U, Riess H, Solh Z, Perry J, Kahale LA, Bossuyt PM, Klerk C, Büller HR, Akl EA, Schünemann HJ. The Khorana score for prediction of venous thromboembolism in cancer patients: An individual patient data meta-analysis. J Thromb Haemost. 2020;18(8):1940-1951. https://doi.org/10.1111/jth.14824
- Wang MM, Qin XJ, He XX, Qiu MJ, Peng G, Yang SL. Comparison and screening of different risk assessment models for deep vein thrombosis in patients with solid tumors. J Thromb Thrombolysis. 2019;48(2):292-298. https://doi.org/10.1007/s11239-019-01840-x
- Yifang H, Jun D, Jingting Y, Ying S, Ping Z, Xiaomei D. Comparison of the PADUA and IMPROVE scores in assessing venous thromboembolism risk in 42257 medical inpatients in China. J Thromb Thrombolysis. 2024;57(5): 775-783. https://doi.org/10.1007/s11239-024-02979-y
- Peng Q, Chen X, Han Y, Tang G, Liu J, Liu Y, Zhou Q, Long L. Applicability of the Padua scale for Chinese rheumatic in-patients with venous thromboembolism. PLoS One. 2022;17(12):e0278157. https://doi.org/10.1371/journal.pone.0278157
- Zhou C, Yi Q, Ge H, Wei H, Liu H, Zhang J, Luo Y, Pan P, Zhang J, Peng L, Aili A, Liu Y, Wang M, Tang Y, Wang L, Zhong X, Wang Y, Zhou H. Validation of Risk Assessment Models Predicting Venous Thromboembolism in Inpatients with Acute Exacerbation Of Chronic Obstructive Pulmonary Disease: A Multicenter Cohort Study in China. Thromb Haemost. 2022;122(7):1177-1185. https://doi.org/10.1055/a-1693-0063
- Cohen AT, Harrington RA, Goldhaber SZ, Hull RD, Wiens BL, Gold A, Hernandez AF, Gibson CM. Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients. N Engl J Med. 2016;375(6):534-544. https://doi.org/10.1056/NEJMoa1601747
- Vedantham S, Goldhaber SZ, Julian JA, Kahn SR, Jaff MR, Cohen DJ, Magnuson E, Razavi MK, Comerota AJ, Gornik HL, Murphy TP, Lewis L, Duncan JR, Nieters P, Derfler MC, Filion M, Gu CS, Kee S, Schneider J, Saad N, Blinder M, Moll S, Sacks D, Lin J, Rundback J, Garcia M, Razdan R, VanderWoude E, Marques V, Kearon C, Investigators AT. Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis. N Engl J Med. 2017;377(23):2240-2252. https://doi.org/10.1056/NEJMoa1615066
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