Aim — to determine the effect of intrapelvic veins enlargement on the symptoms of chronic venous disease (CVD) in patients with concomitant varicose veins of pelvis (VVP) and lower extremities (VVLE). Material and methods. There were 30 patients with VVLE and 45 women with VVLE combined with VVP. CVD CEAP C2 was detected in 47 patients, C3 — in 28 patients. Incidence and severity of varicose, pain and edematous syndromes, heaviness in legs were assessed. All patients underwent duplex ultrasound scanning (DUS) of the veins of the lower extremities and pelvis. Patients were divided into 2 groups: control group — 30 patients with VVLE without pelvic veins pathology; group 2 — 45 patients with VVP and VVLE. Results. There were more severe symptoms of CVD in group 2. Risk of pain in legs was 4 times higher in group 2 compared with group 1 (OR 4.23; 95% CI 1.57—11.39). VVP combined with VVLE was followed by 7-fold increase of the incidence of edema of legs compared with VVLE alone (OR 7.42; 95% CI 2.23—24.78). OR of heaviness in legs was 5 times higher in group 2 than in group 1 (OR = 5.3, 95% CI 1.85—15.07). Varicose syndrome was 2 times more severe in group 2. Conclusion. Intrapelvic veins enlargement is accompanied by higher incidence and severity of CVD in patients with VVP and VVLE.