The results of the using confocal laser endomicroscopy as a screening method in the diagnosis of upper gastrointestinal disease

Sukhikh M.V.; Panchenkov D.N.; Sazonov D.V.; Leneva Y.M.

doi:https://doi.org/10.17116/endoskop20202601121

Sukhikh M.V.

A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia

Panchenkov D.N.

laboratoriia minimal'no invazivnoĭ khirurgii NIMSI MGMSU

SPIN RSCI: 4316-4651
Scopus AuthorID: 41262312000
ORCID: 0000-0001-8539-4392

Sazonov D.V.

FGBU "Federal'nyĭ nauchno-klinicheskiĭ tsentr spetsializirovannykh vidov meditsinskoĭ pomoshchi i meditsinskikh tekhnologiĭ FMBA Rossii", Moskva

Leneva Y.M.

A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia

The results of the using confocal laser endomicroscopy as a screening method in the diagnosis of upper gastrointestinal disease

Authors:

Sukhikh M.V., Panchenkov D.N., Sazonov D.V., Leneva Y.M.

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Journal: Endoscopic Surgery. 2020;26(1): 21‑28

DOI: 10.17116/endoskop20202601121

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To cite this article:

Sukhikh MV, Panchenkov DN, Sazonov DV, Leneva YM. The results of the using confocal laser endomicroscopy as a screening method in the diagnosis of upper gastrointestinal disease. Endoscopic Surgery. 2020;26(1):21‑28. (In Russ.)
https://doi.org/10.17116/endoskop20202601121

Подписка 2026 Эндоскопическая хирургия (Endoscopic Surgery)

Использование инфографики авторами научных работ

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Abstract:

The diagnostic value of an endoscopic examination of the upper gastrointestinal, the identification of foci of early neoplasia, inflammatory diseases for a long time depended on the correctness of the selected section of the mucosa for biopsy. The risk of skipping the pathology of the esophagus and stomach mucosa remains high. Probe based confocal laser endomicroscopy (PBCLEM) is a new technology that allows real-time imaging at the cellular level using miniature optical systems, built into the tip of a small probe. Objective. Evaluation of the effectiveness of PBCLEM as a screening method in the diagnosis of diseases of the esophagus, stomach, and duodenum. Material and methods. The study included 60 patients who underwent video esophagogastroduodenoscopy, the final stage of which was PBCLEM with targeted biopsy. A comparison of the data of macroscopy, endomicroscopy with the findings of histological studies. Results. When conducting PBCLEM revealed a pathology: Epithelial neoplasms of the stomach, duodenum, Barrett esophagus, inflammatory diseases of the esophagus, stomach. Conclusion. Based on the study, it can be argued that PBCLEM, as a screening method for standard gastrointestinal endoscopy, has high specificity, sensitivity and accuracy in the diagnosis of inflammatory diseases of the upper gastrointestinal, metaplastic changes in the esophagus mucosa, and differential diagnosis of epithelial neoplasms.

Keywords:

endoscopic diagnostics

confocal laser endomicroscopy

diseases of the upper gastrointestinal

histology

Authors:

Sukhikh M.V.

A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia

Panchenkov D.N.

laboratoriia minimal'no invazivnoĭ khirurgii NIMSI MGMSU

SPIN RSCI: 4316-4651
Scopus AuthorID: 41262312000
ORCID: 0000-0001-8539-4392

Sazonov D.V.

FGBU "Federal'nyĭ nauchno-klinicheskiĭ tsentr spetsializirovannykh vidov meditsinskoĭ pomoshchi i meditsinskikh tekhnologiĭ FMBA Rossii", Moskva

Leneva Y.M.

A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia

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References:

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