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Smirnova E.A.

Bezhanova S.D.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

Kozlov N.A.

Department of Proctology and Department of Pathomorphology of N.N. Blokhin Russian Research Oncology Center, Moscow, Russia

Bukaeva I.A.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

Raikhlin N.T.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

Stroganova A.M.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

Senderovich A.I.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

Renal cell carcinoma associated with Xp11 translocation involving the gene

Authors:

Smirnova E.A., Bezhanova S.D., Kozlov N.A., Bukaeva I.A., Raikhlin N.T., Stroganova A.M., Senderovich A.I.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2018;80(1): 58‑62

DOI: 10.17116/patol201880158-62

Views: 2228

Downloaded: 99

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Table of contents

RENAL CELL CARCINOMA ASSOCIATED WITH XP11 TRANSLOCATION INVOLVING THE GENE
RENAL CELL CARCINOMA ASSOCIATED WITH XP11 TRANSLOCATION INVOLVING THE GENE

To cite this article:

Smirnova EA, Bezhanova SD, Kozlov NA, Bukaeva IA, Raikhlin NT, Stroganova AM, Senderovich AI. Renal cell carcinoma associated with Xp11 translocation involving the gene. Russian Journal of Archive of Pathology. 2018;80(1):58‑62. (In Russ.)
https://doi.org/10.17116/patol201880158-62

Подписка 2025-2 (Russian Journal of Archive of Pathology)
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The paper describes a clinical case of the rare tumor renal cell carcinoma associated with Xp11 translocations involving the TFE3 gene in a 53-year-old male patient. It provides the detailed characteristics of current diagnostic techniques.

Keywords:

renal cell carcinoma
diagnosis
immunohistochemistry
electron microscopy

Authors:

Smirnova E.A.

Bezhanova S.D.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

Kozlov N.A.

Department of Proctology and Department of Pathomorphology of N.N. Blokhin Russian Research Oncology Center, Moscow, Russia

Bukaeva I.A.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

Raikhlin N.T.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

Stroganova A.M.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

Senderovich A.I.

N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Moscow, Russia

List of references:

  1. Moch H, Humphrey PA, Ulbright TM, Reuter VE. WHO Classification of tumours of the urinary system and male genital organs. Lyon, France: IARC; 2016
  2. Bezhanova SD. Tumors of the kidney. The new 2016 WHO classification of tumors of the genitourinary system. Arkhiv patologii. 2017;79(2):48-52. (In Russ.) https://doi.org/10.17116/patol201779248-52
  3. Argani P, Antonescu CR, Couturier J, Fournet JC, Sciot R, Debiec-Rychter M, Hutchinson B, Reuter VE, Boccon-Gibod L, Timmons C, Hafez N, Ladanyi M. PRCC-TFE3 renal carcinomas: morphologic, immunohistochemical, ultrastructural and molecular analysis of an entity associated with the t (x-1) (p 11.2-q21). Am J Surg Pathol. 2002;26(12):1553-1566. https://doi.org/10.1097/00000478-200212000-00003
  4. Grisendi S, Mecucci C, Falini B, Pandolfi P. Nucleophosmin and cancer. Nat Rev. Cancer. 2006;6(7):493-505. https://doi.org/10.1038/nrc1885
  5. Liu N, Wang Z, Gan W, Xiong L, Miao B, Chen X, Guo H, Li D. Renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusions: clinical features, treatments and prognosis. PLoS One. 2016;11(11):166897. https://doi.org/10.1371/journal.pone.0166897

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