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Malykhin F.Т.

Stavropol State Medical University Ministry of Health of Russia, Stavropol, Russia

Kostornaya I.V.

Stavropol State Medical University Ministry of Health of Russia, Stavropol, Russia

Morphological changes in the respiratory organs in chronic obstructive pulmonary disease

Authors:

Malykhin F.Т., Kostornaya I.V.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2016;78(1): 42‑50

DOI: 10.17116/patol201678142-50

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To cite this article:

Malykhin FТ, Kostornaya IV. Morphological changes in the respiratory organs in chronic obstructive pulmonary disease. Russian Journal of Archive of Pathology. 2016;78(1):42‑50. (In Russ.)
https://doi.org/10.17116/patol201678142-50

Подписка 2025 (Russian Journal of Archive of Pathology)
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The basis for airway remodeling in patients with chronic obstructive pulmonary disease (COPD) is tissue changes contributing to thickening of the walls of the airway and its obstruction. As the disease becomes severer, there are increases in mucosal metaplasia, submucosal hypertrophy, peribronchial fibrosis, and airway smooth muscle mass. Drug therapy for COPD does not virtually lead to regression of airway obstruction, except when eosinophilia is present.

Keywords:

chronic obstructive pulmonary disease
morphological changes
remodeling

Authors:

Malykhin F.Т.

Stavropol State Medical University Ministry of Health of Russia, Stavropol, Russia

Kostornaya I.V.

Stavropol State Medical University Ministry of Health of Russia, Stavropol, Russia

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