Status epilepticus after brain tumor surgery

Lapteva KN, Savin IA, Shimansky VN, Maslennikova MA, Kim DS, Sokolova EYu, Sazonova OB. Status epilepticus after brain tumor surgery. Burdenko's Journal of Neurosurgery. 2023;87(3):65‑73. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20238703165

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

Использование инфографики авторами научных работ

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ABTRACT

BACKGROUND

Status epilepticus (SE) is characterized by continuous course of clinical and/or electrographic epileptic seizures. There are little data on the course and outcomes of SE after resection of brain tumors.

OBJECTIVE

To analyze clinical and electrographic manifestations of SE, its course and outcomes in short-term period after resection of brain tumors.

MATERIAL AND METHODS

We analyzed medical records of 18 patients over 18 years old between 2012 and 2019. All patients underwent resection of brain tumor and developed SE after surgery. Clinical criteria were repeated epileptic seizures without interictal recovery of consciousness, stereotypical motor phenomena, impaired consciousness with continued epileptic activity according to video-EEG data. We analyzed EEG data, neurological status, CT and laboratory data.

RESULTS

Metastases (33%) and meningiomas (16%) prevailed. Supratentorial tumors were observed in 61% of patients. Two patients had preoperative seizures. Non-convulsive SE was diagnosed in 62% of patients. SE was successfully treated in 77% of cases. Mortality rate in patients with SE was 44%.

CONCLUSION

Early postoperative SE is rare after brain tumor surgery (about 0.09%). Nevertheless, this complication is associated with high mortality. Non-convulsive SE is common (62%) that should be considered in postoperative management.

Keywords:

status epilepticus

brain tumors

EEG

Authors:

Lapteva K.N.

Burdenko Neurosurgical Center

ORCID: 0000-0003-1163-7253

Savin I.A.

Burdenko Neurosurgical Center

ORCID: 0000-0003-2594-5441

Shimansky V.N.

Burdenko Neurosurgical Center

ORCID: 0000-0002-3816-847X

Maslennikova M.A.

Moscow Multidisciplinary Clinical Center «Kommunarka»

ORCID: 0000-0001-5142-0361

Kim D.S.

Burdenko Neurosurgical Center

ORCID: 0000-0003-2354-6930

Sokolova E.Yu.

Burdenko Neurosurgical Center

ORCID: 0000-0002-0446-8781

Sazonova O.B.

Burdenko Neurosurgical Center

ORCID: 0000-0002-6204-0062

Received:

03.03.2023

Accepted:

24.03.2023

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References:

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