Central diabetes insipidus after resection of sellar-suprasellar tumors: prevalence and predictors of manifestation

Badmaeva I.N.; Astafyeva L.I.; Kalinin P.L.; Kadashev B.A.; Kutin M.A.

doi:https://doi.org/10.17116/neiro202185051111

Badmaeva I.N.

Burdenko Neurosurgical Center

Astafyeva L.I.

Burdenko Neurosurgical Center

Kalinin P.L.

Burdenko Neurosurgery Center

Kadashev B.A.

Burdenko Neurosurgical Center

Kutin M.A.

Burdenko Neurosurgery Center

Central diabetes insipidus after resection of sellar-suprasellar tumors: prevalence and predictors of manifestation

Authors:

Badmaeva I.N., Astafyeva L.I., Kalinin P.L., Kadashev B.A., Kutin M.A.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2021;85(6): 111‑118

DOI: 10.17116/neiro202185051111

Read: 9586 times

To cite this article:

Badmaeva IN, Astafyeva LI, Kalinin PL, Kadashev BA, Kutin MA. Central diabetes insipidus after resection of sellar-suprasellar tumors: prevalence and predictors of manifestation. Burdenko's Journal of Neurosurgery. 2021;85(6):111‑118. (In Russ., In Engl.)
https://doi.org/10.17116/neiro202185051111

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

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Abstract:

Central diabetes insipidus is a neuroendocrine disorder caused by disturbances in antidiuretic hormone release. The last one is responsible for fluid and electrolyte balance regulation. The most common cause of diabetes insipidus is resection of sellar-suprasellar tumors followed by damage to hypothalamic nuclei responsible for antidiuretic hormone release, disruption of antidiuretic hormone transportation from hypothalamus or its release by neurohypophysis. According to various data, postoperative diabetes insipidus occurs in 13—30% of cases. The highest risk of diabetes insipidus is observed after resection of craniopharyngioma, Rathke’s cleft cyst and ACTH-releasing pituitary microadenoma. This review is devoted to prevalence and predictors of diabetes insipidus after resection of sellar-suprasellar tumors.

Keywords:

transsphenoidal surgery

diabetes insipidus

adipsia

pituitary adenoma

craniopharyngioma

Rathke’s cleft cyst

Cushing’s disease

pituitary stalk

desmopressin

Authors:

Badmaeva I.N.

Burdenko Neurosurgical Center

Astafyeva L.I.

Burdenko Neurosurgical Center

Kalinin P.L.

Burdenko Neurosurgery Center

Kadashev B.A.

Burdenko Neurosurgical Center

Kutin M.A.

Burdenko Neurosurgery Center

Received:

27.11.2020

Accepted:

05.08.2021

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References:

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