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Kiselev D.V.
Yaroslavl State Medical University
Lavrukhin V.V.
Yaroslavl Clinical Hospital No 2
The use of a fixed combination of diclofenac and orphenadrine in the treatment of acute pain syndrome in patients with discogenic lumbosacral radiculopathy and lumboischialgia
Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(3): 122‑129
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To cite this article:
Kiselev DV, Lavrukhin VV. The use of a fixed combination of diclofenac and orphenadrine in the treatment of acute pain syndrome in patients with discogenic lumbosacral radiculopathy and lumboischialgia. S.S. Korsakov Journal of Neurology and Psychiatry.
2023;123(3):122‑129. (In Russ.)
https://doi.org/10.17116/jnevro2023123031122
Acute pain syndromes caused by discogenic lumbosacral radiculopathy and lumboischialgia are not uncommon in clinical practice and characterized by a high risk of becoming chronic. The pathogenetic aspects, features of the clinical picture, existing approaches to conservative treatment of these conditions are analyzed in this paper. Data on the efficacy and safety of a fixed combination of diclofenac and orphenadrine (Neodolpasse) use in the treatment of vertebrogenic pain syndromes based on the NEODOLEX study results are presented, and the authors’ own clinical observations are given. Possible reasons for the high efficacy of Neodolpasse in patients with discogenic radiculopathies and nonspecific back and neck pain are discussed.
Keywords:
Authors:
Kiselev D.V.
Yaroslavl State Medical University
Lavrukhin V.V.
Yaroslavl Clinical Hospital No 2
Received:
23.01.2023
Accepted:
24.01.2023
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