Asthenic disorders in schizophrenia (schizoasthenia) on the model of hypochondriac schizophrenia

Ivanov S.V.; Kharkova G.S.; Giatsintova A.A.; Voronova E.I.

doi:https://doi.org/10.17116/jnevro20211210217

Ivanov S.V.

Mental Health Research Center

ORCID: 0000-0001-9532-7150

Kharkova G.S.

Mental Health Research Centre

ORCID: 0000-0002-6864-5679

Giatsintova A.A.

Blokhin National Medical Research Center of Oncology

ORCID: 0000-0002-2858-7304

Voronova E.I.

Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

ORCID: 0000-0001-6605-4851

Asthenic disorders in schizophrenia (schizoasthenia) on the model of hypochondriac schizophrenia

Authors:

Ivanov S.V., Kharkova G.S., Giatsintova A.A., Voronova E.I.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(2): 7‑12

DOI: 10.17116/jnevro20211210217

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To cite this article:

Ivanov SV, Kharkova GS, Giatsintova AA, Voronova EI. Asthenic disorders in schizophrenia (schizoasthenia) on the model of hypochondriac schizophrenia. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(2):7‑12. (In Russ.)
https://doi.org/10.17116/jnevro20211210217

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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OBJECTIVE

To determine the structure and mechanisms of interaction of asthenic disorders with negative and positive psychopathological symptoms in hypochondriac schizophrenia.

MATERIAL AND METHODS

The study included male and female patients, aged 17—69 years, with a diagnosis of hypochondriac schizophrenia (F20.80 according to ICD-10) and asthenia symptoms. The main research method was clinical, which was supplemented by pathopsychological examination and the use of psychometric scales (PANSS, SANS, MFI-20,VAS asthenia).

RESULTS AND CONCLUSION

Asthenia in case of hypochondriac schizophrenia (schizoasthenia) integrates two unrelated phenomena: «weakness» and «exhaustion» (intolerance to stress), and also acts within the framework of three psychopathological syndromes: neurotic, senestopathic/hypochondriac and overvalued hypochondria. Asthenia with hypochondriac schizophrenia is a predictor of an unfavorable social and clinical prognosis. Integrating into the structure of the clinical manifestations of hypochondriac schizophrenia, asthenia forms close relationships with positive and negative disorders of the type of «general syndromes», but remains outside the categories of both positive and negative symptoms of the disease, thus forming a separate «dimension» in the psychopathological space of schizophrenia.

Keywords:

schizoasthenia

hypochondriac schizophrenia

adaptation

neuroimmunology

Authors:

Ivanov S.V.

Mental Health Research Center

ORCID: 0000-0001-9532-7150

Kharkova G.S.

Mental Health Research Centre

ORCID: 0000-0002-6864-5679

Giatsintova A.A.

Blokhin National Medical Research Center of Oncology

ORCID: 0000-0002-2858-7304

Voronova E.I.

Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

ORCID: 0000-0001-6605-4851

Received:

17.06.2020

Accepted:

29.06.2020

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