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Klinkova A.S.

FGU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdravsotsrazvitiia Rossii

Kamenskaia O.V.

Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina Minzdravsotsrazvitiia RF

Ashurkov A.V.

Meshalkin National Medical Research Center of Healthcare Ministry of Russia, Novosibirsk, Russia

Murtazin V.I.

Meshalkin National medical research center of the Ministry of Health of the Russian Federation, Novosibirsk, Russia

Lomivorotov V.V.

E.N.Meshalkin National Medical Research Center under the Ministry of Health of the Russia, Novosibirsk, 630055, Russia

Karas'kov A.M.

FGBU "Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdravsotsrazvitiia Rossii

Factors of adverse prediction of application of spinal cord stimulation with chronic pain syndrome in patients with critical lower limb ischemia

Authors:

Klinkova A.S., Kamenskaia O.V., Ashurkov A.V., Murtazin V.I., Lomivorotov V.V., Karas'kov A.M.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(9): 23‑30

DOI: 10.17116/jnevro201911909123

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Table of contents

FACTORS OF ADVERSE PREDICTION OF APPLICATION OF SPINAL CORD STIMULATION WITH CHRONIC PAIN SYNDROME IN PATIENTS WITH CRITICAL LOWER LIMB ISCHEMIA
FACTORS OF ADVERSE PREDICTION OF APPLICATION OF SPINAL CORD STIMULATION WITH CHRONIC PAIN SYNDROME IN PATIENTS WITH CRITICAL LOWER LIMB ISCHEMIA

To cite this article:

Klinkova AS, Kamenskaia OV, Ashurkov AV, Murtazin VI, Lomivorotov VV, Karas'kov AM. Factors of adverse prediction of application of spinal cord stimulation with chronic pain syndrome in patients with critical lower limb ischemia. S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(9):23‑30. (In Russ.)
https://doi.org/10.17116/jnevro201911909123

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

Objective. To study the clinical dynamics in the long-term period after spinal cord stimulation (SCS) in patients with chronic pain syndrome and critical lower limb ischemia (CLLI) and to identify factors affecting the prognosis of SCS. Material and methods. The clinical dynamics was analyzed in 48 patients with pain syndrome and CLLI 1 year after SCS. Microcirculatory blood flow (MBF) was studied in the affected foot by laser-doppler flowmetry (LDF) (Perfusion Units (PU)) and transcutaneous oximetry (TcpO2, mmHg.) using an occlusive test before and after SCS. The factors associated with negative clinical dynamics 1 year after SCS were determined. Results. In 74% of cases, SCS contributes to the improvement of clinical status (reduction of pain syndrome, increase in motor activity, healing of ulcers). After SCS, according to LDF and TcpO2, the authors observed an increase in MBF and tissue metabolism — from 1.3 (0.7—2.8) to 6.2 (3.8—8.7) PU and from 14.5 (7.5—22.1) to 41.1 (26.4—57.6) mmHg, respectively with normalization of the MBF reserve during the occlusion test. Negative clinical dynamics after SCS is associated with high comorbidity, TcO2 <10 mmHg and the duration of pain. Conclusion. SCS contributes to the improvement of the clinical status of patients with chronic pain syndrome and CLLI. The negative dynamics is associated with high comorbidity, TcrO2 <10 mmHg and the duration of pain.

Keywords:

chronic pain syndrome
lower limb ischemia
spinal cord stimulation

Authors:

Klinkova A.S.

FGU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdravsotsrazvitiia Rossii

Kamenskaia O.V.

Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina Minzdravsotsrazvitiia RF

Ashurkov A.V.

Meshalkin National Medical Research Center of Healthcare Ministry of Russia, Novosibirsk, Russia

Murtazin V.I.

Meshalkin National medical research center of the Ministry of Health of the Russian Federation, Novosibirsk, Russia

Lomivorotov V.V.

E.N.Meshalkin National Medical Research Center under the Ministry of Health of the Russia, Novosibirsk, 630055, Russia

Karas'kov A.M.

FGBU "Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdravsotsrazvitiia Rossii

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