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Erichev A.N.

Bekhterev Saint Petersburg Psychoneurological Research Institute;
Mechnikov North-Western State Medical University

Kotsyubinsky A.P.

Bekhterev National Medical Research Center for Psychiatry and Neurology

Kuznetsova S.L.

Bekhterev Saint Petersburg Psychoneurological Research Institute

Depression as a biopsychosocial problem

Authors:

Erichev A.N., Kotsyubinsky A.P., Kuznetsova S.L.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(5‑2): 7‑11

DOI: 10.17116/jnevro20211210527

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Table of contents

DEPRESSION AS A BIOPSYCHOSOCIAL PROBLEM
DEPRESSION AS A BIOPSYCHOSOCIAL PROBLEM

To cite this article:

Erichev AN, Kotsyubinsky AP, Kuznetsova SL. Depression as a biopsychosocial problem. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(5‑2):7‑11. (In Russ.)
https://doi.org/10.17116/jnevro20211210527

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
 
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Abstract:

The article discusses the role of biological and psychological adaptive and compensatory mechanisms in the aetiology and pathogenesis of affective disorders, the relationship between the genetic characteristics of an individual, which determine vulnerability, and epigenetic mechanisms dependent on external psychosocial influences. The role of psychological factors disrupted the consistency of mental functions and the preservation of individuality that determines the psychogenesis of the disease both at the borderline and at the psychotic level is indicated. The psychoprophylactic and therapeutic role of psychotherapy is substantiated with an analysis of its influence both on the biological parameters of the brain and on the psychological characteristics of an individual, including an assessment of the quality of life. A comprehensive biopsychosocial approach to a spectrum of affective disorders makes a significant contribution to the development of personalized person-centered medicine, considering the phenomenological characteristics of the disease, as well as the psychological characteristics of patients and the nature of their social adaptation, which increases the effectiveness of treatment and rehabilitation of mentally ill patients.

Keywords:

affective disorders
early stressful events
psychotherapy
bio-psycho-social rehabilitation approach

Authors:

Erichev A.N.

Bekhterev Saint Petersburg Psychoneurological Research Institute;
Mechnikov North-Western State Medical University

Kotsyubinsky A.P.

Bekhterev National Medical Research Center for Psychiatry and Neurology

Kuznetsova S.L.

Bekhterev Saint Petersburg Psychoneurological Research Institute

Received:

01.03.2021

Accepted:

26.03.2021

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