The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.
Anuriev A.M.
Irkutsk State Medical Academy of Postgraduate Education — Branch Campus of the Russian Medical Academy of Continuing Professional Education, Irkutsk, Russia
Gorbachev V.I.
Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuous Professional Education of the Ministry of Health of Russia, Irkutsk, Russia
Hypoxic-ischemic brain damage in premature newborns
Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(8‑2): 63‑69
Views: 76628
Downloaded: 1036
To cite this article:
Anuriev AM, Gorbachev VI. Hypoxic-ischemic brain damage in premature newborns. S.S. Korsakov Journal of Neurology and Psychiatry.
2019;119(8‑2):63‑69. (In Russ.)
https://doi.org/10.17116/jnevro201911908263
One of the main causes of cerebral dysfunction in premature newborns is hypoxia. High mortality and lifelong morbidity in these children is a frequent result of neonatal hypoxic brain damage. The article presents some data on the prevalence of neurological diseases that have arisen in the perinatal period, and highlights the key etiological factors leading to hypoxia in both the intranatal and early postnatal periods. The pathogenesis of hypoxic-ischemic brain lesions in premature infants is described in detail. At the same time, more careful consideration is given to the glutathione system, which protects against lipid peroxidation, the glutamate-calcium cascade, and the excitotoxicity mediated by it, as well as the processes of necrosis and apoptosis of nerve cells. The advantages and disadvantages of modern methods for diagnosing cerebral lesions are noted, and the principles of treatment of these disorders are analyzed.
Authors:
Anuriev A.M.
Irkutsk State Medical Academy of Postgraduate Education — Branch Campus of the Russian Medical Academy of Continuing Professional Education, Irkutsk, Russia
Gorbachev V.I.
Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuous Professional Education of the Ministry of Health of Russia, Irkutsk, Russia
List of references:
Close metadata
Email Confirmation
An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.
Email Confirmation
Log in to the site using your account in one of the services
We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.