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Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Batysheva T.T.

Poliklinika vosstanovitel'nogo lecheniia #7

Mel'nikov M.V.

Kafedra obshcheĭ khirurgii Sankt-Peterburgskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. I.I. Mechnikova

Boĭko O.V.

Moskovskiĭ gorodskoĭ tsentr rasseiannogo skleroza na baze Gorodskoĭ klinicheskoĭ bol'nitsy #11

Mugutdinova B.T.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova

Gorina T.P.

Nauchno-prakticheskiĭ tsentr detskoĭ psikhonevrologii

Ovcharov V.V.

Moskovskiĭ gorodskoĭ tsentr rasseiannogo skleroza (gorodskaia klinicheskaia bol'nitsa #11 Departamenta zdravookhraneniia Moskvy);
kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universtiteta

Bykova O.V.

Detskaia klinicheskaia psikhonevrologicheskaia bol'nitsa #18, kabinet detskogo rasseiannogo skleroza, Moskva

Popova N.F.

kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
gorodskaia klinicheskaia bol'nitsa #11

Gusev E.I.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Assessment of the size of the thalamus as a method for the evaluation of the activity of neurodegenerative process after the treatment with cerebrolisin in young patients with multiple sclerosis

Authors:

Boĭko A.N., Batysheva T.T., Mel'nikov M.V., Boĭko O.V., Mugutdinova B.T., Gorina T.P., Ovcharov V.V., Bykova O.V., Popova N.F., Gusev E.I.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(2‑2): 104‑110

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To cite this article:

Boĭko AN, Batysheva TT, Mel'nikov MV, et al. . Assessment of the size of the thalamus as a method for the evaluation of the activity of neurodegenerative process after the treatment with cerebrolisin in young patients with multiple sclerosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(2‑2):104‑110. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

The aim of the study was to describe the atrophy of the thalamus in young patients with active relapsing multiple sclerosis (MS) treated with cerebrolysin. Eighteen MS patients (mean age 20.10±0.45 years) with disease onset in childhood or adolescence were studied. Neurological examination using the EDSS, neuropsychological testing and MRI were used. At baseline, MRI revealed the hypotrophy of the thalamus that was not correlated with the performance on neuropsychological tests. After treatment with cerebrolysin, there was the decrease in the level of atrophy that suggested the neuroprotective effect of this drug. This effect was more prominent in younger patients with the high frequency of previous relapses.

Keywords:

multiple sclerosis
thalamus
neurodegeration
cerebrolysin
multiple sclerosis
thalamus
neurodegeration
cerebrolysin

Authors:

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Batysheva T.T.

Poliklinika vosstanovitel'nogo lecheniia #7

Mel'nikov M.V.

Kafedra obshcheĭ khirurgii Sankt-Peterburgskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. I.I. Mechnikova

Boĭko O.V.

Moskovskiĭ gorodskoĭ tsentr rasseiannogo skleroza na baze Gorodskoĭ klinicheskoĭ bol'nitsy #11

Mugutdinova B.T.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova

Gorina T.P.

Nauchno-prakticheskiĭ tsentr detskoĭ psikhonevrologii

Ovcharov V.V.

Moskovskiĭ gorodskoĭ tsentr rasseiannogo skleroza (gorodskaia klinicheskaia bol'nitsa #11 Departamenta zdravookhraneniia Moskvy);
kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universtiteta

Bykova O.V.

Detskaia klinicheskaia psikhonevrologicheskaia bol'nitsa #18, kabinet detskogo rasseiannogo skleroza, Moskva

Popova N.F.

kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
gorodskaia klinicheskaia bol'nitsa #11

Gusev E.I.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

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