Results of a sociological research studying characteristics of reintegration of people with multiple sclerosis (MS) in a society are presented. During the research, people with MS living in the territory of the Samara region and experts, representatives of a region profile medical community, have been interrogated. The analysis of medical and social factors influencing the process of rehabilitation of the target group of patients is given. The role of Samara regional public organization of disabled people with MS (structural division of the All-Russian Multiple Sclerosis Society) in the improvement of quality of medical and socially-psychological help to people with MS is studied.