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Trufanov S.V.

Research Institute of Eye Diseases

Fisenko N.V.

Krasnov Research Institute of Eye Diseases

Molecular genetic aspects of Fuchs’ endothelial corneal dystrophy pathogenesis

Authors:

Trufanov S.V., Fisenko N.V.

More about the authors

Journal: Russian Annals of Ophthalmology. 2020;136(5): 260‑267

DOI: 10.17116/oftalma2020136052260

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Table of contents

MOLECULAR GENETIC ASPECTS OF FUCHS’ ENDOTHELIAL CORNEAL DYSTROPHY PATHOGENESIS
MOLECULAR GENETIC ASPECTS OF FUCHS’ ENDOTHELIAL CORNEAL DYSTROPHY PATHOGENESIS

To cite this article:

Trufanov SV, Fisenko NV. Molecular genetic aspects of Fuchs’ endothelial corneal dystrophy pathogenesis. Russian Annals of Ophthalmology. 2020;136(5):260‑267. (In Russ.)
https://doi.org/10.17116/oftalma2020136052260

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
 
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Abstract:

Fuchs’ corneal dystrophy (FCD) is a common bilateral non-inflammatory endothelial pathology. It is a multigenic disorder with various expressivity, penetrance and population prevalence. This review discusses corneal endothelium pump function, FCD pathogenesis and its known genetic factors.

Keywords:

cornea
mutation
Fuchs’ endothelial dystrophy
TCF4
ZEB1
SLC4A11
LOXHD1
AGBL1

Authors:

Trufanov S.V.

Research Institute of Eye Diseases

Fisenko N.V.

Krasnov Research Institute of Eye Diseases

Received:

05.05.2020

Accepted:

20.05.2020

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