Glaucoma surgery: from traditional filtration techniques to modern principles of bioengineering

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The article reviews the history of glaucoma surgery and analyses the connection between the accumulation of knowledge on glaucoma progression and the emergence of effective surgical treatment methods based on glaucoma pathogenesis. It also describes modern principles of preventing filtering bleb scarring. Particular attention is devoted to biodegradable collagen matrix implants.

Keywords:

glaucoma

excessive scarring

hypotensive effect

biodegradable collagen matrix implant

Authors:

Mamikonian V.R.

Uchrezhdenie Rossiĭskoĭ akademii meditsinskikh nauk "NII glaznykh bolezneĭ RAMN", Moskva

Fisenko N.V.

Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021;
I.M. Sechenov First Moscow State Medical University, Ophthalmology Department, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991

SPIN RSCI: 9750-1529
Scopus AuthorID: 57192992418
ORCID: 0000-0001-7198-4498

List of references:

Natsional’noe rukovodstvo po glaukome dlya praktikuyushchikh vrachei. Pod red. Egorova EA, Astakhova YuS, Ericheva VP. M.: GEOTAR-Media; 2015. (In Russ.)
European Glaucoma Society. Terminology and guidelines for glaucoma. 4^th edition ed: Savona, Italy PubliComm 2014; 2014.
Tham Y, Li X, Wong T, Quigley H, Aung T, Cheng C. Global prevalence of glaucoma and projections of glaucoma burden through 2040. A systematic review and meta-analysis. Ophthalmology. 2014;121:2081-2090. https://doi.org/10.1016/j.ophtha.2014.05.013
Avetisov SE, Mamikonyan VR, Kazaryan EE, Shmeleva-Demir OA, Mazurova YuV, Ryzhkova EG, Galoyan NS, Tatevosyan AA. A new screening method for determining tolerant intraocular pressure. Vestnik oftal’mologii. 2009;125(5):3-7. (In Russ.)
Mackenzie W. Practical Treatise on the Diseases of the Eye. London: Longmarts, Reese, Orme Brown and Green; 1830;710.
Graefe A von. Uber die Iridectomie bei Glaucom und den glaucomatosen Process. Graefes Arch Clin Fxp Ophthalmol. 1857;3:456-555. https://doi.org/10.1007/bf02720732
Wecker L. Sclerotomie simple et combine. Ann d’ocul. 1894;25:112.
Lagrange F. Iridectomie et sclerectomie dans le treatment du glaucoma chronique. Arch d’ophthalmol. 1906;26:481-496.
Holth S. Ein neues Prinzip der operative Behandlung des Glaucoms. Ber Dtch Ophthal. 1906;33:123-128.
Elliot R. A treatise on glaucoma. 2nd Ed. Frowde, Hodder and Stoughton: London, 1922.
Cairns J. Trabeculectomy. Preliminary report of a new method. Am J Ophthalmol. 1968;66(4):673-679. https://doi.org/10.1016/0002-9394(68)91288-9
Watson P, Barnett F. Effectiveness of trabeculectomy in glaucoma. Am J Ophthalmol. 1975;79:831-845.
Krasnov MM. Mikrokhirurgiya glaukom. M.: Meditsina; 1980. (In Russ.)
Schwartz K, Budenz D. Current management of glaucoma. Curr Opin Ophthalmol. 2004;15:119-126. https://doi.org/10.1097/00055735-200404000-00011
Serov VV, Shekhter AB. Soedinitel’naya tkan’: funktsional’naya morfologiya i obshchaya patologiya. M.: Meditsina; 1981. (In Russ.)
Shaarawy TM, Sherwood MB, Hitchings R., et al. Glaucoma. Vol. 2: Surgical Management. Second edition ed: Elsevier; 2015.
Erichev VP, Egorov EA. On pathogenesis of primary open-angle glaucoma. Vestnik oftal’mologii. 2014;130(6):98-105. (In Russ.)
Cordeiro M, Schultz G, Ali R, Bhattacharya S, Khaw P. Molecular therapy in ocular wound healing. Br J Ophthalmol. 1999;83:1219-1224. https://doi.org/10.1136/bjo.83.11.1219
Chang L, Crowston J, Cordeiro M, Akbar A, Khaw P. The Role of the Immune System in Conjunctival Wound Healing After Glaucoma. Surgery Surv Ophthalmol. 2000;45:49-68. https://doi.org/10.1016/s0039-6257(00)00135-1
Agarwal R, Gupta S, Agarwal P, Saxena R, Agrawal S. Current concepts in the pathophysiology of glaucoma. Indian J Ophthalmol. 2009;57:257-266. https://doi.org/10.4103/0301-4738.53049
Taurone S, Ripandelli G, Pacella E, Bianchi E, Plateroti A, De Vito S, Plateroti P, Grippaudo F, Cavallotti C, Artico M. Potential regulatory molecules in the human trabecular meshwork of patients with glaucoma: immunohistochemical profile of a number of inflammatory cytokines. Mol Med Rep. 2015;11(2):1384-1390. https://doi.org/10.3892/mmr.2014.2772
Tezel G. Oxidative Stress in Glaucomatous Neurodegeneration: Mechanisms and Consequences. Prog Retin Eye Res. 2006;25(5):490-513. https://doi.org/10.1016/j.preteyeres.2006.07.003
Cohen L, Graham T, Fry W. Beta radiation; as an adjunct to glaucoma surgery in the Negro. Am J Ophthulmol. 1959;47:54-61. https://doi.org/10.1016/s0002-9394(14)78140-1
Lama P, Fechtner R. Antifibrotics and wound healing in glaucoma surgery. Surv Ophthalmol. 2003;48:314-346. https://doi.org/10.1016/s0039-6257(03)00038-9
Khaw P, Sherwood M, MacKay S. Five-minute treatments with fluorouracil, floxuridine, and mitomycin have long-term effects on human Tenon’s capsule fibroblasts. Arch Ophthalmol. 1992;110:1150-1154. https://doi.org/10.1001/archopht.1992.01080200130040
Rothman R, Liebmann J, Ritch R. Low-dose 5-fluorouracil trabeculectomy as initial surgery in uncomplicated glaucoma: long-term follow up. Ophthalmology. 2000;107:1184-1190. https://doi.org/10.1016/s0161-6420(00)00085-3
The Fluorouracil Filtering Surgery Study Group: Five-year follow-up of the Fluorouracil Filtering Surgery Study. Am J Ophthalmol. 1996;121:349-366. https://doi.org/10.1016/s0002-9394(14)70431-3
Palanca-Capistrano A, Hall J, Cantor L, Morgan L, Hoop J, WuDunn D. Long-term outcomes of intraoperative 5 fluorouracil versus intraoperative mitomycin C in primary trabeculectomy surgery. Ophthalmology. 2009;116:185-190. https://doi.org/10.1016/j.ophtha.2008.08.009
Towler H, McCluskey P, Shaer B, Lightman S. Long-term follow-up of trabeculectomy with intraoperative 5-fluorouracil for uveitis-related glaucoma. Ophthalmology. 2000;107:1822-1828. https://doi.org/10.1016/s0161-6420(00)00351-1
Reibaldi A, Uva M, Longo A. Nine-year follow-up of trabeculectomy with or without low-dosage mitomycin-c in primary open-angle glaucoma. Br J Ophthalmol. 2008;92:1666-1670. https://doi.org/10.1136/bjo.2008.140939
Jacobi P, Dietlein T, Krieglstein G. Adjunctive mitomycin C in primary trabeculectomy in young adults: a long-term study of case-matched young patients. Graefes Arch Clin Exp Ophthalmol. 1998;236:652-657. https://doi.org/10.1007/s004170050137
Fontana H, Nouri-Mahdavi K, Caprioli J. Trabeculectomy with mitomycin C in pseudophakic patients with open-angle glaucoma: outcomes and risk factors for failure. Am J Ophthalmol. 2006;141:652-659. https://doi.org/10.1016/j.ajo.2005.11.039
Istranov LP, Istranova LV, Sychennikov IA. Collagen: morphology, characteristics, application in medicine. Farmatsiya. 1984;5:76-79. (In Russ.)
Henriksen K, Karsdal M. Type I Collagen. In: Karsdal M. eds. Biochemistry of collagens, laminins and elastin. Structure, function and biomarkers. Elsevier Inc. 2016;1-11.
Parenteau-Bareil R, Gauvin R, Berthod F. Collagen-based biomaterials for tissue engineering applications. Materials. 2010;3:1863-1887. https://doi.org/10.3390/ma3031863
Mulberger J, Carmichael P. Experimental implants of collagen sponge material in rabbit eyes. Am J Ophthalmol. 1962;54(1):19-20. https://doi.org/10.1016/0002-9394(62)93990-9
Baranov IYa, Bortsov VN, Konstantinova LM. On differentiated surgical treatment of principal forms of refractory glaucoma. Vestnik oftal’mologii. 1991;3:9-13. (In Russ.)
Dzhaliashvili OA, Ignat’ev AN, Zhozhos Kh. Potential causes of ocular hypertension after trabeculectomy and ways of its reduction. Vestnik oftal’mologii. 1992;3:3-5. (In Russ.)
Anisimov SI, Anisimova SYu, Larionov EV, Avtandilov GG, Dushin NV, Rogacheva IV. Experimental and clinical research of collagen drainage usage for antiglaucomatous operations. Klinicheskaya oftal’mologiya. 2006;7(2):73-76. (In Russ.)
Anisimova SYu, Anisimov SI, Rogacheva IV, Panasyuk AF, Larionov EV. New non-absorbed collagen implant increases the efficacy of the non-penetrating deep sclerlimbectomy. Glaukoma. 2003;1:19-23. (In Russ.)
Chen H, Ritch R, Krupin T, Hsu W. Control of Filtering Bleb Structure through Tissue Bioengineering: An Animal Model. Invest Ophthalmol Vis Sci. 2006;47:5310-5314. https://doi.org/10.1167/iovs.06-0378
Hsu W, Ritch R, Krupin T, Chen H. Control of Filtering Bleb Structure through Tissue bioengineering for surgical bleb defects:an animal study Graefes. Arch Clin Exp Ophthalmol. 2008;246:709-717. https://doi.org/10.1007/s00417-007-0744-9
Zelefsky J, Hsu W, Ritch R. Biodegradable collagen matrix implant for trabeculectomy. Expert Rev Ophthalmol. 2008;3(6):613-617. https://doi.org/10.1586/17469899.3.6.613
Papaconstantinou D, Georgalas I, Karmiris E, Diagourtas A, Koutsandrea C, Ladas I, Apostolopoulos M, Georgopoulos G. Trabeculectomy with OloGen versus trabeculectomy for the treatment of glaucoma: a pilot study. Acta Ophthalmol. 2010;88:80-85. https://doi.org/10.1111/j.1755-3768.2009.01753.x
Cillino S, Di Pace F, Cillino G, Casuccio A. Biodegradable collagen matrix implant vs mitomycin-C as an adjuvant in trabeculectomy: a 24-month, randomized clinical trial. Eye. 2011;25:1598-1606. https://doi.org/10.1038/eye.2011.219
Cillino S, Casuccio A, Di Pace F, Cagini C, Ferraro L, Cillino G. Biodegradable collagen matrix implant versus mitomycin-C in trabeculectomy: five-year follow-up. BMC Ophthalmology. 2016;16:24. https://doi.org/10.1186/s12886-016-0198-0
Rosentreter A, Gaki S, Claus Cursiefen C, Dietlein T. Trabeculectomy using Mitomycin C versus an atelocollagen implant: clinical results of a randomized trial and histopathologic findings. Ophthalmologica. 2014;231:133-140. https://doi.org/10.1159/000356400
Dada T, Kusumesh R, Bali S, Sharma S, et al. Trabeculectomy with combined use of subconjunctival collagen implant and low-dose Mitomycin C. J Glaucoma. 2013;22(8):659-662. https://doi.org/10.1097/ijg.0b013e3182594f5b

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