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Arkhipova O.A.

Institute of the Clinical Cardiology named after A.L. Myasnikov of National Medical Research Center for Cardiology, Moscow, Russia

Martynyuk t.V.

The Institute of Clinical Cardiology named after A.L. Myasnikov, Federal State Institution «National Medical Research Center of Сardiology», Moscow, Russia

Chazova I.E.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

A clinical case of long-term macitentan therapy in a female patient with idiopathic pulmonary hypertension

Authors:

Arkhipova O.A., Martynyuk t.V., Chazova I.E.

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Journal: Therapeutic Archive. 2016;88(12): 88‑93

DOI: 10.17116/terarkh2016881288-93

Read: 2279 times

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Table of contents

A CLINICAL CASE OF LONG-TERM MACITENTAN THERAPY IN A FEMALE PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSION
A CLINICAL CASE OF LONG-TERM MACITENTAN THERAPY IN A FEMALE PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSION

To cite this article:

Arkhipova OA, Martynyuk tV, Chazova IE. A clinical case of long-term macitentan therapy in a female patient with idiopathic pulmonary hypertension. Therapeutic Archive. 2016;88(12):88‑93. (In Russ.)
https://doi.org/10.17116/terarkh2016881288-93

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Abstract:

In late 2015, the Russian Federation registered the new non-selective endothelin receptor antagonist macitentan for the pathogenetic therapy of pulmonary arterial hypertension. The given clinical case demonstrates the possibility of using macitentan in a female patient with idiopathic pulmonary hypertension and its ability to affect the clinical, hemodynamic, and functional status of patients and to slow down the progression of the disease.

Keywords:

idiopathic pulmonary hypertension
endothelin receptor antagonists
macitentan

Authors:

Arkhipova O.A.

Institute of the Clinical Cardiology named after A.L. Myasnikov of National Medical Research Center for Cardiology, Moscow, Russia

Martynyuk t.V.

The Institute of Clinical Cardiology named after A.L. Myasnikov, Federal State Institution «National Medical Research Center of Сardiology», Moscow, Russia

Chazova I.E.

Federal State budget organization National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation, The Institute of Clinical Cardiology, Moscow, Russia

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References:

  1. Martynyuk T.V., Nakonechnikov S.N., Chazova I.E. Matsitentan: evolyutsiya klassa antagonistov retseptorov endotelina dlya povysheniya effektivnosti i bezopasnosti lecheniya legochnoi arterial'noi gipertenzii. Evraziiskii kardiologicheskii zhurnal. 2013;2:15-26.
  2. Chazova I.E., Avdeev S.N., Tsareva N.A., Volkov A.V., Martynyuk T.V., Nakonechnikov S.N. Klinicheskie rekomendatsii po diagnostiki i lecheniyu legochnoi arterial'noi gipertenzii. Terapevticheskii arkhiv. 2014;86(9):4-23.
  3. Pulido T, Adzerikho I, Channick RN et al. Macitentan and morbidity and mortality in pulmonary arterial hypertension. N Engl J Med. 2013;369(9):865-866. doi:10.1056/NEJMoa1213917
  4. Galiè N, Humbert M, Vachiery JL. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J. 2015;46:903-975. doi:10.1093/eurheartj/ehv317
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