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Koludarova E.M.

Russian Center of Forensic Medical Expertise Ministry of Health of the Russian Federation

Tuchik E.S.

Russian Center of Forensic Medical Expertise Ministry of Health of the Russian Federation

Microscopic assessment of cerebral edema in fatal traumatic brain injury during the first hour of the post-traumatic period

Authors:

Koludarova E.M., Tuchik E.S.

More about the authors

Journal: Forensic Medical Expertise. 2026;68(1): 26‑29

DOI: 10.17116/sudmed20266901126

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MICROSCOPIC ASSESSMENT OF CEREBRAL EDEMA IN FATAL TRAUMATIC BRAIN INJURY DURING THE FIRST HOUR OF THE POST-TRAUMATIC PERIOD
MICROSCOPIC ASSESSMENT OF CEREBRAL EDEMA IN FATAL TRAUMATIC BRAIN INJURY DURING THE FIRST HOUR OF THE POST-TRAUMATIC PERIOD

To cite this article:

Koludarova EM, Tuchik ES. Microscopic assessment of cerebral edema in fatal traumatic brain injury during the first hour of the post-traumatic period. Forensic Medical Expertise. 2026;68(1):26‑29. (In Russ.)
https://doi.org/10.17116/sudmed20266901126

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To study the diagnostic histological signs of cerebral edema in traumatic brain injury (TBI) in the post-traumatic period up to 1 hour.

MATERIAL AND METHODS

A retrospective analysis of archival materials from forensic medical examinations was conducted, and brain fragments from corpses of people who died from TBI within 1 hour after the injury were examined using the IHC method.

RESULTS

The revealed histological changes represent a set of signs of traumatic vascular injury, blood-brain barrier, neurons, astrocytes and their irreversible changes in the foci of traumatic hemorrhages. The presence of cytotoxic (swelling of cells) in the penumbra area with initial symptoms of vasogenic edema cannot be considered as a morphological substrate of cerebral edema, determining the immediate cause of death.

CONCLUSIONS

To determine the cause of death, it is necessary to conduct a targeted study of the brain to search for traumatic hemorrhages in vital brain centers and irreversible changes in them, using modern original methods of sectional examination.

Keywords:

traumatic brain injury
cerebral edema
microscopic assessment
forensic medical examination

Authors:

Koludarova E.M.

Russian Center of Forensic Medical Expertise Ministry of Health of the Russian Federation

Tuchik E.S.

Russian Center of Forensic Medical Expertise Ministry of Health of the Russian Federation

Received:

31.07.2025

Accepted:

19.08.2025

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References:

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