Characteristics of histochemical, molecular genetic and radiation-induced liver changes depending on the postmortem interval

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The aim of this study is to analyze literature data on postmortem changes in the liver and their use in determination of postmortem interval. Biological death expectedly causes the development of postmortem disorders not only in the liver structure, but also changes in its biochemical and histochemical parameters. Literature data about changes of histochemical, immunohistochemical and biomolecular characteristics of liver tissue, as well as bacterial migration to the liver depending on the duration of postmortem period, are presented. The effectiveness of radiology for visualization of postmortem changes and, accordingly, for determining the postmortem interval is noted.

Keywords:

liver

postmortem changes

autolysis

postmortem interval

Authors:

Shchegolev A.I.

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after academician V.I. Kulakov

ORCID: 0000-0002-2111-1530

Tumanova U.N.

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after academician V.I. Kulakov

ORCID: 0000-0002-0924-6555

Savva O.V.

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after academician V.I. Kulakov;
Bureau of Forensic Medicine named after D.I. Mastbaum

ORCID: 0000-0002-0926-5609

Received:

01.06.2022

Accepted:

23.06.2022

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