About the effect of ethanol on the level of substances of low and medium molecular weight

Edelev I.S.; Andriyanova N.A.; Obukhova L.M.; Edelyev N.S.

doi:https://doi.org/10.17116/sudmed20226502120

Edelev I.S.

Nizhny Novgorod regional Bureau of forensic medical examination

Andriyanova N.A.

Nizhny Novgorod regional Bureau of forensic medical examination

Obukhova L.M.

Privolzhsky research medical University

Edelyev N.S.

Volga Research Medical University of the Ministry of Health of Russia

About the effect of ethanol on the level of substances of low and medium molecular weight

Authors:

Edelev I.S., Andriyanova N.A., Obukhova L.M., Edelyev N.S.

More about the authors

Journal: Forensic Medical Expertise. 2022;65(2): 20‑23

DOI: 10.17116/sudmed20226502120

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To cite this article:

Edelev IS, Andriyanova NA, Obukhova LM, Edelyev NS. About the effect of ethanol on the level of substances of low and medium molecular weight. Forensic Medical Expertise. 2022;65(2):20‑23. (In Russ.)
https://doi.org/10.17116/sudmed20226502120

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)

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Abstract:

The aim of this work is to study the effect of the concentration of ethanol in the blood on the level of low and medium molecular weight substances in the urine and blood of corpses. The content of LMMWS in the blood and urine of corpses without ethanol in the blood and its concentration of 0.5—1.5 ‰ and 2.0—5.0 ‰ was determined by the method of Malakhova modified by Kopytova at wavelengths of 238—298 nm. The dependence of the concentration of LMMWS in urine on the concentration of ethanol in the blood is shown: the decrease in the parameters of LMMWS in urine is the more pronounced, the higher the concentration of ethanol in the blood. One of the probable mechanisms of such a decrease is the neurotoxic effect of ethanol, leading to polyuria and a decrease in the concentration of various substances in the urine.

Keywords:

substances of low and medium molecular weight

ethanol concentration

blood

urine

Authors:

Edelev I.S.

Nizhny Novgorod regional Bureau of forensic medical examination

Andriyanova N.A.

Nizhny Novgorod regional Bureau of forensic medical examination

Obukhova L.M.

Privolzhsky research medical University

Edelyev N.S.

Volga Research Medical University of the Ministry of Health of Russia

Received:

23.06.2021

Accepted:

26.07.2021

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References:

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