A method for examining the biochemical composition of dental tissues in human teeth

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Izotov B.N.

Association of laboratory specialists and organizations "Federation of laboratory medicine"

Velenko P.S.

Department of Forensic Medicine, I.M. Sechenov First Moscow State Medical University, Russian Ministry of Health, Moscow, Russia, 119435

Lisovskaya S.B.

Department of Analytical Toxicology, Pharmaceutical Chemistry and Pharmacognosy, Institute of Pharmacy and Translational Medicine, Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia, 128018

Zolotenkova G.V.

Kafedra sudebnoĭ meditsiny Pervogo MGMU im. I.M. Sechenova

Bashilov A.A.

Department of Analytical Toxicology, Pharmaceutical Chemistry and Pharmacognosy, Institute of Pharmacy and Translational Medicine, Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia, 128018

A method for examining the biochemical composition of dental tissues in human teeth

Authors:

Izotov B.N., Velenko P.S., Lisovskaya S.B., Zolotenkova G.V., Bashilov A.A.

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Journal: Forensic Medical Expertise. 2019;62(5): 39‑42

DOI: 10.17116/sudmed20196205139

Read: 1336 times

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To cite this article:

Izotov BN, Velenko PS, Lisovskaya SB, Zolotenkova GV, Bashilov AA. A method for examining the biochemical composition of dental tissues in human teeth. Forensic Medical Expertise. 2019;62(5):39‑42. (In Russ.)
https://doi.org/10.17116/sudmed20196205139

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)

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Abstract:

In medical literature there is no single detailed standard for studying the biochemical composition of a tooth. This circumstance led to the development of a proprietary method for determining the enantiomers of aspartic acid in hard dental tissues for use in the further study of the relationship between the amino acid composition of dental tissues and the biological age of humans. Dental tissue samples obtained from living individuals aged from 20 to 50 years were studied by chromatography-mass spectrometry. The results of the study allowed us to put forward a number of practical recommendations on the standardization of the procedure for the preparation of dental tissue samples and the parameters of chromatography-mass spectrometry research.

Keywords:

age-related changes

dental tissues of teeth

amino acid racemization

chromatography

mass spectrometry

Authors:

Izotov B.N.

Association of laboratory specialists and organizations "Federation of laboratory medicine"

Velenko P.S.

Department of Forensic Medicine, I.M. Sechenov First Moscow State Medical University, Russian Ministry of Health, Moscow, Russia, 119435

Lisovskaya S.B.

Department of Analytical Toxicology, Pharmaceutical Chemistry and Pharmacognosy, Institute of Pharmacy and Translational Medicine, Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia, 128018

Zolotenkova G.V.

Kafedra sudebnoĭ meditsiny Pervogo MGMU im. I.M. Sechenova

Bashilov A.A.

Department of Analytical Toxicology, Pharmaceutical Chemistry and Pharmacognosy, Institute of Pharmacy and Translational Medicine, Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia, 128018

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References:

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