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Pigolkin Yu.I.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Dolzhansky O.V.

Petrovsky Russian Research Center for Surgery, Moscow, Russia

Pal'tseva E.M.

Laboratoriia élektronnoĭ mikroskopii i immunogistokhimii Tsentralizovannogo patologoanatomicheskogo otdeleniia GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova" Minzdravsotsrazvitiia Rossii

Shylova M.A.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Fedorov D.N.

RNTsKh im. akad. B.V. Petrovskogo RAMN, Moskva

Boeva S.E.

Department of Forensic Medicine, I.M. Sechenov First Moscow State Medical University, Russian Ministry of Health, Moscow, Russia, 119991

The forensic medical evaluation of traumatic and spontaneous ruptures of the organs affected by the tumours

Authors:

Pigolkin Yu.I., Dolzhansky O.V., Pal'tseva E.M., Shylova M.A., Fedorov D.N., Boeva S.E.

More about the authors

Journal: Forensic Medical Expertise. 2017;60(2): 49‑56

DOI: 10.17116/sudmed201760249-56

Read: 5490 times

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Table of contents

THE FORENSIC MEDICAL EVALUATION OF TRAUMATIC AND SPONTANEOUS RUPTURES OF THE ORGANS AFFECTED BY THE TUMOURS
THE FORENSIC MEDICAL EVALUATION OF TRAUMATIC AND SPONTANEOUS RUPTURES OF THE ORGANS AFFECTED BY THE TUMOURS

To cite this article:

Pigolkin YuI, Dolzhansky OV, Pal'tseva EM, Shylova MA, Fedorov DN, Boeva SE. The forensic medical evaluation of traumatic and spontaneous ruptures of the organs affected by the tumours. Forensic Medical Expertise. 2017;60(2):49‑56. (In Russ.)
https://doi.org/10.17116/sudmed201760249-56

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The present article was designed to report the results of the analysis of the cases of traumatic and spontaneous ruptures of the organs affected by the tumours based on the original observations and the literature data. It is shown that the probability of the tumour rupture depends on its histological type, localization, the size, and the distance from the capsule of the affected organ, the degree of involvement of the major blood vessels, the severity of the necrotic changes, the presence of cysts in the neoplasm, and the regimens of radio- and chemotherapy. Moreover, the rupture can be facilitated by anticoagulation therapy, intake or oral contraceptives, pregnancy, concomitant diseases, alcoholic intoxication, splenomegaly, and hypocoagulation resulting from dissemination of the neoplastic process or the metastatic lesions of the liver. Even a minimal injury to the skin can provoke the tumour rupture associated with the fatal hemorrhage. A delayed rupture within a few hours or days is possible.

Keywords:

tumour
injury
rupture
forensic medicine

Authors:

Pigolkin Yu.I.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Dolzhansky O.V.

Petrovsky Russian Research Center for Surgery, Moscow, Russia

Pal'tseva E.M.

Laboratoriia élektronnoĭ mikroskopii i immunogistokhimii Tsentralizovannogo patologoanatomicheskogo otdeleniia GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova" Minzdravsotsrazvitiia Rossii

Shylova M.A.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Fedorov D.N.

RNTsKh im. akad. B.V. Petrovskogo RAMN, Moskva

Boeva S.E.

Department of Forensic Medicine, I.M. Sechenov First Moscow State Medical University, Russian Ministry of Health, Moscow, Russia, 119991

Close metadata

References:

  1. Pigolkin YuI, Sidorovich YuV. Characteristic of mortality in the Russian Federation. Sudebno-meditsinskaya ekspertiza. 2011;54(11):14-18. (In Russ.).
  2. Sudebnaya meditsina i sudebno-meditsinskaya ekspertiza: natsional'noe rukovodstvo. Pod red. Pigolkina YuI. M.: GEOTAR-Media. 2014;728. (In Russ.).
  3. Gross A, Próchnicka B. Intraventricular hemorrhage originating from choroid plexus angioma in a road accident victim. Z Rechtsmed. 1989;102(6):409-413.
  4. Chhiber SS, Singh JP. Acute spontaneous subdural hematoma of arterial origin: a report of four cases and review of literature. Neurol India. 2010;58(4):654-658. doi: 10.4103/0028-3886.68698
  5. Menon A, Kanchan T, Lobo FD, Menezes RG. Pontine cavernous haemangioma — an incidental autopsy finding. J Forensic Leg Med. 2009;16(7):417-419. doi: 10.1016/j.jflm.2009.04.005 Epub 2009 May 1
  6. Høyer CB, Ulhøi BP, Charles AV. The unexpected finding of a benign mature teratoma in a forensic pathology autopsy: a rare cause for sudden, unexpected death. Am J Forensic Med Pathol. 2013;34(4):302-305. doi: 10.1097/PAF.0b013e3182a18983
  7. Vinogradova TP. Trauma and tumor. Arkhiv patologii. 1976;38(9):76-84. (In Russ.).
  8. Rothschild MA, Maxeiner H. Spontaneous subdural hemorrhage of natural cause in metastatic renal cell carcinoma. Beitr Gerichtl Med. 1990;48:223-237.
  9. Goktalay T, Yaldiz S, Ozgen Alpaydin A, Goktan C, Celik P. An unusual presentation of bronchial rupture. Respir Care. 2011;56(6):858-860. doi: 10.4187/respcare.01012 Epub 2011 Feb 11
  10. Moore EE, Moore FA. American Association for the Surgery of Trauma Organ Injury Scaling: 50th anniversary review article of the Journal of Trauma. J Trauma. 2010;69(6):1600-1601. doi: 10.1097/TA.0b013e318201124e
  11. Choi YK, Kim KC. Spontaneous pneumothorax as the first manifestation of lung cancer: two case report. J Thorac Dis. 2015;7(8):E252-e254. doi: 10.3978/j.issn.2072-1439.2015.07.31
  12. Avila Martínez RJ, Hernández Voth A, Villena Garrido V. Spontaneous hemothorax as a presenting form of bronchogenic carcinoma. Arch Bronconeumol. 2013;49(10):455. doi: 10.1016/j.arbres.2013.02.008 Epub 2013 Apr 18
  13. Tsuda K, Nishi M, Yamada K, Yamamoto K. Spontaneous hemothorax in a patient with lung metastases of osteosarcoma. Masui. 2005;54(9):1027-1029.
  14. Bazan F, Vollmer I, Gayete A. Chemotherapy-induced secondary pneumothorax. Arch Bronconeumol. 2014;50(1):44. doi: 10.1016/j.arbres.2013.06.007 Epub 2013 Oct 8
  15. Yoshida J, Kajiwara T, Akao M, Tanimura A. Hemopneumothorax and hemoperitoneum in a case with large cell carcinoma of the lung. Jpn J Thorac Cardiovasc Surg. 2000;48(3):190-193.
  16. Tatokoro M, Kawakami S, Sakura M, Kobayashi T, Kihara K, Akamatsu H. Successful management of life-threatening choriocarcinoma syndrome with rupture of pulmonary metastatic foci causing hemorrhagic shock. Int J Urol. 2008;15(3):263-264. doi: 10.1111/j.1442-2042.2007.01979.x
  17. Hammes SR, Krymskaya VP. Targeted approaches toward understanding and treating pulmonary lymphangioleiomyomatosis (LAM). Horm Cancer. 2013;4(2):70-77. doi: 10.1007/s12672-012-0128-4 Epub 2012 Nov 27
  18. Nemoto K, Itoh M, Senba S, Shimizudani N, Adachi H, Kishi K, Ohishi S, Nakamura H, Matsuoka T. A case of lung cancer mimicking rupture of a thoracic aortic aneurysm. Nihon Kokyuki Gakkai Zasshi. 2009;47(2):158-162.
  19. Sakhri L, Meynet E, Ferrer L, Pirvu A, Ferretti G, Moro-Sibilot D. Atypical response to erlotinib in a patient with metastatic lung adenocarcinoma: a case report. J Med Case Rep. 2014;8:335. doi: 10.1186/1752-1947-8-335
  20. Chung WP, Song HL, Ho CL, Chiu NT, Su WC. Gastric perforation secondary to regression of lung adenocarcinoma after gefitinib treatment. J Clin Oncol. 2013;31(1):e6-E8. doi: 10.1200/JCO.2012.43.5578 Epub 2012 Nov 19
  21. Soh J, Toyooka S, Gobara H, Hiraki T, Sugimoto S, Yamane M, Oto T, Kanazawa S, Miyoshi S. A case of delayed massive hemothorax caused by the rupture of a pulmonary artery pseudoaneurysm after radiofrequency ablation of lung tumors. Jpn J Clin Oncol. 2012;42(7):646-649. doi: 10.1093/jjco/hys068 Epub 2012 May 11
  22. Gedik E, Girgin S, Aldemir M, Keles C, Tuncer MC, Aktas A. Non-traumatic splenic rupture: report of seven cases and review of the literature. World J Gastroenterol. 2008;14(43):6711-6716.
  23. Leong CW, Menon T, Rao S. Post-traumatic intrahepatic splenosis mimicking a neuroendocrine tumour. BMJ Case Rep. 2013;2013. pii: bcr2012007885. doi: 10.1136/bcr-2012-007885
  24. Bergmann T, Larsen SB. Splenosis around the internal genitalia — a rare late complication following trauma to the spleen. Ugeskr Laeger. 2011;173(23):1656-1657.
  25. Kalitievskii PF. Makroskopicheskaya differentsial'naya diagnostika patologicheskikh protsessov. M.: Meditsina. 1987. (In Russ.).
  26. Abrikosov AI. Chastnaya patologicheskaya anatomiya. M.—L.: Medgiz. 1947. (In Russ.).
  27. Bogomolov DV, Dolzhanskiĭ OV. Hemorrhagic pseudocyst of the pancreas with spontaneous rupture of the spleen. Arkhiv patologii. 2002;64(4):44-46.
  28. Nestok BR, Goldstein JD, Lipkovic P. Splenic rupture as a cause of sudden death in undiagnosed chronic myelogenous leukemia. Am J Forensic Med Pathol. 1988;9(3):241-245.
  29. Kyriacou A, Arulraj N, Varia H. Acute abdomen due to spontaneous splenic rupture as the first presentation of lung malignancy: a case report. J Med Case Rep. 2011;5:444. doi: 10.1186/1752-1947-5-444
  30. Giagounidis AA, Burk M, Meckenstock G, Koch AJ, Schneider W. Pathologic rupture of the spleen in hematologic malignancies: two additional cases. Ann Hematol. 1996;73(6):297-302.
  31. Fernandes LR, dos Santos CL, Costa F, Barata F. Spontaneous splenic rupture in a patient with small-cell lung cancer. BMJ Case Rep. 2013;2013. pii: bcr2013010325. doi: 10.1136/bcr-2013-010325
  32. Maria PS, Mauri M, Carmignani L. A unique cause of hemoperitoneum: spontaneous rupture of a splenic hemangiopericytoma. Int J Emerg Med. 2011;4(1):13. doi: 10.1186/1865-1380-4-13
  33. Stupnik T, Vidmar S, Hari P. Spontaneous rupture of a normal spleen following bronchoplastic left lung lower lobectomy. Interact Cardiovasc Thorac Surg. 2008;7(2):290-291. doi: 10.1510/icvts.2007.165803 Epub 2008 Jan 17
  34. Oinonen R, Franssila K, Elonen E. Spontaneous splenic rupture in two patients with a blastoid variant of mantle cell lymphoma. Ann Hematol. 1997;74(1):33-35.
  35. Kawashima I, Sueki Y, Yamamoto T, Hamanaka S, Nozaki Y, Nakajima K, Mitsumori T, Kirito K. Non-traumatic splenic rupture during the chemotherapy and successful management by emergency splenectomy in a patient with blastic plasmacytoid dendritic cell neoplasm. Rinsho Ketsueki. 2013;54(6):584-586.
  36. Suárez-Peñaranda JM, de la Calle MC, Rodrìguez-Calvo MS, Muñoz JI, Concheiro L. Rupture of liver cell adenoma with fatal massive hemoperitoneum resulting from minor road accident. Am J Forensic Med Pathol. 2001;22(3):275-277.
  37. Burke M, Opeskin K. Spontaneous rupture of the liver associated with a primary angiosarcoma: case report. Am J Forensic Med Pathol. 2000;21(2):134-137.
  38. Miyamoto M, Sudo T, Kuyama T. Spontaneous rupture of hepatocellular carcinoma: a review of 172 Japanese cases. Am J Gastroenterol. 1991;86(1):67-71.
  39. Jr MA, Papaiordanou F, Gonçalves JM, Chaib E. Spontaneous rupture of hepatic hemangiomas: A review of the literature. World J Hepatol. 2010;2(12):428-433. doi: 10.4254/wjh.v2.i12.428
  40. Park KK, Yang SI, Yoon MH. One stage resection of spontaneous rupture of hepatocellular carcinoma in the triangular ligament with diaphragm invasion: case report and review of the literature. World J Emerg Surg. 2012;7(1):30. doi: 10.1186/1749-7922-7-30
  41. Occhionorelli S, Dellachiesa L, Stano R, Cappellari L, Tartarini D, Severi S, Palini GM, Pansini GC, Vasquez G. Spontaneous rupture of a hepatic epithelioid angiomyolipoma: damage control surgery. A case report. G Chir. 2013;34(11-12):320-322.
  42. Wu J, Tong RL, Ding CF, Zhou J, Xu XF, Wang WL, Xu X, Zheng SS. Establishment of prediction model for spontaneous rupture of primary liver cancer. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2014;43(6):652-657.
  43. Pehar M, Vukoja I, Rozić D, Mišković J. Spontaneous diaphragmatic rupture related to local invasion by retroperitoneal liposarcoma. Ann R Coll Surg Engl. 2012;94(1):e18-e19. doi: 10.1308/003588412X13171221499423
  44. Dai H, Ding H, Liu F, Yao Z, Li L, Li C, Tan Y, Wang J. Complications of chemoembolization for hepatic neoplasms. Saudi Med J. 2007;28(8):1208-1212.
  45. Hammond NA, Lostumbo A, Adam SZ, Remer EM, Nikolaidis P, Yaghmai V, Berggruen SM, Miller FH. Imaging of adrenal and renal hemorrhage. Abdom Imaging. 2015;40(7):2747-2760. doi: 10.1007/s00261-015-0453-5
  46. Sebastià MC, Pérez-Molina MO, Alvarez-Castells A, Quiroga S, Pallisa E. CT evaluation of underlying cause in spontaneous subcapsular and perirenal hemorrhage. Eur Radiol. 1997;7(5):686-690.
  47. Katabathina VS, Katre R, Prasad SR, Surabhi VR, Shanbhogue AK, Sunnapwar A. Wunderlich syndrome: cross-sectional imaging review. J Comput Assist Tomogr. 2011 Jul-Aug;35(4):425-433. doi: 10.1097/RCT.0b013e3182203c5e
  48. Tazumi A, Nakanishi S, Meguro S, Kakinuma Y, Moore JE, Millar BC, Matsuda MBr Occurrence and characterisation of intervening sequences (IVSs) within 16S rRNA genes from two atypical campylobacter species, c. sputorum and c. curvus. J Biomed Sci. 2010;67(2):77-81.
  49. Takamatsu S, Nagano H, Ohtsukasa S, Kawachi Y, Maruyama H. A case of spontaneous ruptured solid pseudopapillary tumor of pancreas resected by laparoscopic surgery. Case Rep Med. 2013;2013:953240. doi: 10.1155/2013/953240 Epub 2013 Apr 30
  50. Naganuma S, Honda K, Noriki S, Kimura S, Murakami M, Koneri K, Katayama K, Yamaguchi A, Itoh H. Ruptured mucinous cystic neoplasm with an associated invasive carcinoma of pancreatic head in a pregnant woman: report of a case and review of literature. Pathol Int. 2011;61(1):28-33. doi: 10.1111/j.1440-1827.2010.02609.x Epub 2010 Nov 3
  51. Smith WM, Lucas JG, Frankel WL. Splenic rupture: a rare presentation of pancreatic carcinoma. Arch Pathol Lab Med. 2004;128(10):1146-1150.
  52. Chirman SB. Rupter of the normal spleen and cancer of the pancreas. Calif Med. 1965;102:227-230.
  53. Gómez Hernández MT, Franch-Arcas G, González Sánchez C, Sánchez-Jiménez R, Cerro-Martínez M. Retroperitoneal haemorrhage after traumatic rupture of a phaechromocytoma. Cir Esp. 2013;91(3):197-199. doi: 10.1016/j.ciresp.2011.11.014 Epub 2012 Mar 14
  54. Ausania F, De-Giorgio F, Valerio L, Capelli A, Arena V. Neoplastic spread after trauma: natural death or manslaughter? Med Sci Law. 2010;50(2):100-102.
  55. Pang C, Wu P, Zhu G. A Rare Cavernous Hemangioma of the Adrenal Gland. Urol Case Rep. 2015;3(4):120-122. doi: 10.1016/j.eucr.2015.03.009 eCollection 2015
  56. Lu CY, Yen TH, Hsieh ML, Chen Y. Spontaneous rupture of adrenocortical carcinoma: a coincidence or a tendency? Clin Nephrol. 2009;72(2):147-150.
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