The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Grudianov A.I.

Federal'noe gosudarstvennoe biudzhetnoe uchrezhdenie "Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii" Minzdravsotsrazvitiia Rossiĭskoĭ Federatsii, Moskva

Tkacheva O.N.

Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia

Hatagov A.T.

FGBU «TsNIIS i ChLH» Minzdrava RF, Moskva, Rossija

Mustafina F.N.

Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii Minzdrava RF, Moskva

Gorshkov A.Yu.

National Research Center for Preventive Medicine, Moscow, Russia

The impact of periodontal disease treatment on endothelium of sublingual microvessels

Authors:

Grudianov A.I., Tkacheva O.N., Hatagov A.T., Mustafina F.N., Gorshkov A.Yu.

More about the authors

Journal: Stomatology. 2016;95(4): 9‑12

DOI: 10.17116/stomat20169549-12

Read: 908 times

Download PDF (RU)
Contact the author
Table of contents

THE IMPACT OF PERIODONTAL DISEASE TREATMENT ON ENDOTHELIUM OF SUBLINGUAL MICROVESSELS
THE IMPACT OF PERIODONTAL DISEASE TREATMENT ON ENDOTHELIUM OF SUBLINGUAL MICROVESSELS

To cite this article:

Grudianov AI, Tkacheva ON, Hatagov AT, Mustafina FN, Gorshkov AYu. The impact of periodontal disease treatment on endothelium of sublingual microvessels. Stomatology. 2016;95(4):9‑12. (In Russ.)
https://doi.org/10.17116/stomat20169549-12

Подписка 2026 Стоматология (Stomatology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Substantiation of the anti-inflammatory effect of photodynamic therapy in periodontal diseases. Russian Journal of Stomatology. 2025;(1):40-45
Dental status of indi­viduals invo­lved in power training non-professionally. Russian Journal of Stomatology. 2025;(2):57-60
Asso­ciations between sali­vary mela­tonin and periodontal disease: a systematic review and meta-analysis. Stomatology. 2025;(3):87-96
Oral hygiene and hygiene of remo­vable dentures in periodontal patients with cardiometabolic diso­rders. Russian Journal of Operative Surgery and Clinical Anatomy. 2025;(3):48-52
The role of capi­llaroscopy in asse­ssing the effe­ctiveness of non-medicamental treatment methods. (Literature review). Problems of Balneology, Physiotherapy and Exercise Therapy. 2025;(5):63-66
Abstract:

The intactness degree of glycocalyx and the thickness of endothelium layer in sublingual microvessels was determined by means of darkfield microscopy and GlycoCheck RI software in 35 patients (19 men and 16 women, aged 35 to 65 years) with chronic generalized severe periodontitis before and after anti-inflammatory and surgical treatment. The patients were divided into two groups. The first group recieved only local anti-inflammatory therapy while patients of group 2 underwent surgical intervention on the periodontium in addition to local anti-inflammatory therapy. In both groups the changes of parameters of endothelial glycocalyx (EGC) in the early stages of treatment were not significant. In long terms the changes were not revealed in group 1, but in group 2 6 months after surgical treatment in all patients the decrease in the thickness of the permeable glycocalyx decreased and increase of the volume of red blood cells filling was observed.

Keywords:

glycocalyx
periodontal disease
GlycoCheck RI
darkfield microscopy
cardiovascular pathology
capillaroscopy

Authors:

Grudianov A.I.

Federal'noe gosudarstvennoe biudzhetnoe uchrezhdenie "Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii" Minzdravsotsrazvitiia Rossiĭskoĭ Federatsii, Moskva

Tkacheva O.N.

Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia

Hatagov A.T.

FGBU «TsNIIS i ChLH» Minzdrava RF, Moskva, Rossija

Mustafina F.N.

Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii Minzdrava RF, Moskva

Gorshkov A.Yu.

National Research Center for Preventive Medicine, Moscow, Russia

Close metadata

References:

  1. Deanfield J.E., Halcox J.P., Rabelink T.J. (Endothelial function and dysfunction: testing and clinical relevance. Circulation. 2007;115:1285–1295. doi:10.1002/9780470988473.ch14
  2. Reitsma S., Slaaf D.W., Vink H., van Zandvoort M.A., oude Egbrink M.G. The endothelial glycocalyx: composition, functions, and visualization. Pflugers Arch 2007 454: 345–359. doi:10.1007/s00424-007-0212-8
  3. Weinbaum S., Tarbell J.M., Damiano E.R. The structure and function of the endothelial glycocalyx layer. Annual Review of Biomedical Engineering. 2007; 9: 121–167. doi:10.1146/annurev.bioeng.9.060906.151959
  4. Dane M.J.C., van den Berg B.M., Avramut M.C., Faas F.G.A., van der Vlag J., et al. Glomerular Endothelial Surface Layer Acts as a Barrier against Albumin Filtration. American Journal of Pathology. 2013; 182: 1532–1540. doi:10.1016/j.ajpath.2013.01.049
  5. Rabelink T.J., de Boer H.C., van Zonneveld A.J. Endothelial activation and circulating markers of endothelial activation in kidney disease. Nature Reviews Nephrology. 2010; 6: 404–414. Doi:10.1038/nrneph.2010.65
  6. Schmidt E.P., Yang Y., Janssen W.J., Gandjeva A., Perez M.J., et al. The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. Nature Medicine. 2012; 18: 1217. doi:10.1038/nm.2843
  7. Reitsma S., Oude Egbrink M.G., Heijnen V.V., Megens R.T., Engels W., et al. Endothelial glycocalyx thickness and platelet-vessel wall interactions during atherogenesis. Thrombosis and Haemostasis. 2011; 106: 939–946. doi: 10.1160/th11-02-0133
  8. Grubanov A. I., Zorina O. A. Methods of diagnosis of inflammatory periodontal diseases: Guide for physicians. M: Medical information Agency. 2009; 112 p. (In Russ)
  9. Starling E.H. On the Absorption of fluids from the Connective Tissue Spaces. J Physiol 1986; 19(4): 312-326. doi:10.1113/jphysiol.1896.sp000596
  10. Maksimenko A.V., Tarashev A. D. the Functions and condition of the endothelial glycocalyx in norm and pathology: Atherosclerosis and dyslipidemia. Journal of Atherosclerosis and Dyslipidemia, 2011; - 4-17c. (In Russ)
  11. Pries A.R., Secomb T.W., Jacobs H. et al. Microvascular blood flow resistance : role of endothelial surface layer. Journal of Biomechanics 1997; 273 - 5, Pt 2: H2272-H2279. doi: 10.1016/s0021-9290(06)84324-1
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.