The content of phosphoinositides and their metabolites in blood components in patients with chronic generalized periodontitis

Zorina O.A.

GBOU VPO "Pervyĭ MGMU imeni I.M. Sechenova"

Antidze M.K.

GBOU VPO "Pervyĭ MGMU imeni I.M. Sechenova"

Aĭmadinova N.K.

Kafedra stomatologii FPPOV GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova" Minzdrava RF

Muranova I.N.

Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova

The content of phosphoinositides and their metabolites in blood components in patients with chronic generalized periodontitis

Authors:

Zorina O.A., Antidze M.K., Aĭmadinova N.K., Muranova I.N.

More about the authors

Journal: Stomatology. 2012;91(5): 11‑13

Downloaded: 5

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Zorina OA, Antidze MK, Aĭmadinova NK, Muranova IN. The content of phosphoinositides and their metabolites in blood components in patients with chronic generalized periodontitis. Stomatology. 2012;91(5):11‑13. (In Russ.)

Close metadata

Recommended articles:

Prevalence of periodontal disease among adolescents in the Nenets autonomous area. Stomatology. 2025;(1):57-62

Associations of smoking status with the composition of fatty acids in blood plasma in men in Novosibirsk («ESSE-RF3» in the Novosibirsk region). Russian Journal of Preventive Medicine. 2024;(6):36-41

Development of a method for moxonidine quantification in blood and urine by high-performance liquid chromatography with tandem mass-selective detection. Forensic Medical Expertise. 2024;(6):42-47

Methodology for performing intralaboratory quality control in establishing species of the blood by IgGtotal with the use of quantitative enzyme-linked immunosorbent assay. Forensic Medical Expertise. 2025;(1):38-42

Scanning electron microscopy in hemotology. Laboratory Service. 2025;(1):38-47

The aim of the study was to evaluate the content of phosphoinositides (PI) and their metabolites in blood components to reveal the diagnostic value of these in patients with chronic generalized periodontitis. Forty-five patients (30 female and 15 male aged 21-55) with chronic generalized periodontitis, as well as 30 patients with no signs of periodontal disease were included in the study. The PI content differ significantly between the groups thus making it possible using them as diagnostic and follow-up markers.

Keywords:

periodontal inflammatory disease

biochemical markers

phosphoinositides

blood components

Authors:

Zorina O.A.

GBOU VPO "Pervyĭ MGMU imeni I.M. Sechenova"

Antidze M.K.

GBOU VPO "Pervyĭ MGMU imeni I.M. Sechenova"

Aĭmadinova N.K.

Kafedra stomatologii FPPOV GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova" Minzdrava RF

Muranova I.N.

Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova

List of references:

Berridzh M.Dzh. Molekulyarnye osnovy vnutrikletochnoi kommunikatsii. V mire nauki 1985; 12: 98-109.
Grudyanov A.I., Zorina O.A., Petrukhina N.B., Serebryakova L.E. Sposob diagnostiki stepeni tyazhesti parodontita. Patent RF №22280874 ot 16.02.04.
Dmitrieva L.A. Sovremennye aspekty klinicheskoi parodontologii. M: MEDpress 2001; 128.
Zinchenko V.P., Dolgacheva L.P. Vnutrikletochnaya signalizatsiya. Pod red. prof. A.Yu. Budantseva. Pushchino: Elektronnoe izdatel'stvo "Analiticheskaya mikroskopiya" 2003; 84.
Kankanyan A.N., Leont'ev V.K. Bolezni parodonta (novye podkhody v etiologii, patogeneze, diagnostike, profilaktike i lechenii). Erevan 1998; 360.
Krutetskaya Z.I., Lebedev O.E., Kurilova L.S. Mekhanizmy vnutrikletochnoi signalizatsii. SPb: Izd-vo SPb universiteta 2003; 208.
Rukovodstvo po immunofarmakologii: Per. s angl. Pod red. M.M. Deila, Dzh. K. Formena. M: Meditsina 1998; 332.
Strel'nikov V., Slyusar' N., Shcherbakov A. Prognozirovanie rezul'tatov implantatsii po dannym fosfatidilinozitov krovi (FI). Klin impl i stomatol 1998; 1: 4: 39-42.
Tkachuk V.A. Fosfoinozitidnyi obmen i ostsillyatsiya ionov Sa2+. Obzor. Biokhimiya 1998; 63: 1: 47-56.
Eberhard J., Jepsen S., Albers H.K., Açil Y. Quantitation of arachidonic acid metabolites in small tissue biopsies by reversed-phase high-performance liquid chromatography. Anal Biochem 2000; 280: 2: 258-263.
Lombroso M., Nicosia S., Paolettietal. The use of stable prostaglandins to investigate prostacyclin (PGI2)-binding sites and sensitive adenylatecyclase in human platelet membranes. Prostaglandins 1984; 27: 2: 321-333.
Mundy G.R. Inflammatory mediators and the destruction of bone. J Periodont Res 1991; 26: 213-217.
Noguchi K., Ishikawa I. The roles of cyclooxygenase-2 and prostaglandin E2 in periodontal disease. Periodontol 2000; 2007; 43: 85-101.
Queiroz-Junior C.M., Pacheco C.M., Maltos K.L., Caliari M.V., Duarte I.D., Francischi J.N. Role of systemic and local administration of selective inhibitors of cyclo-oxygenase 1 and 2 in an experimental model of periodontal disease in rats. J Periodontal Res 2009; 44: 2: 153-160.
Reddy S. Essentials of clinical periodontology and periodontics. Jaypee Brothers Medical Publishers (P) Ltd 2008; 494.
Saffar J.L. Arachidonic acid derivatives in periodontitis. J Parodontol 1990; 9: 2: 163-167.
Van Dyke T.E., Lester M.A., Shapira L. The role of host response in periodontal disease progression: Implications for future treatment strategies. J Periodontol 1993; 64: 792-806.

Close metadata