The treatment of temporary molars was effected by means of pulpotomy with the use of various materials. All these preparations provided the favourable outcome of the treatment in a large fraction of the patient. Studies of the gingival fluid from the temporary teeth affected by pulpitis have demonstrated a two-fold increase in the levels of 1-beta interleukin and lactoferrin that were absent in the fluid obtained from the subjects having no dental problems. The amount of 1-beta interleukin in the gingival fluid from the children was normal within 12 months after their treatment with the use of VisсoStat combination with the zinc oxide-eugenol cement whereas lactoferrin was virtually absent as soon as 6 months after the treatment. Also, lactoferrin failed to be found in the gingival fluid from the patients of all the study groups in the end of the 12 month follow-up period.