The present study included 93 patients presenting with vascular disorders in the maxillofacial region. Surgical treatment with the use of laser obliteration was given to 73 patients whereas the remaining 20 ones underwent traditional surgical treatment and sclerotherapy. In the former case, a Nd:YAG laser (operated at a wavelength of 1064 nm) and a diode laser (0.98 mcm) were used in the pulse-periodic regime with a mean radiation power of 2-5 W. Contact (intratissue), non-contact, and combined methods were employed. Primary diagnostics was based on the results of ultrasonic studies. Clinical studies with the use of diode and Nd:YAG lasers yielded similar results. The volume of vascular structures decreased to 60-70% of the initial volume within 7 days after surgery; at the same time, they became compacted. All the patients reported the reduced pain reaction and postoperative oedema compared with those given traditional surgical treatment and sclerosing therapy. The scars remaining after the laser treatment were virtually indiscernible. It is concluded that the surgical treatment with the use of laser obliteration decreases injuriousness of intervention in the patients with vascular disorders in the maxillofacial region, results in the good aesthetic outcome, and significantly improves the quality of medical care at large.