Infusion-transfusion therapy is the basic component of the treatment of massive postpartum hemorrhage. For a long time, infusion therapy (IT), using various types of solutions, was based only on empirical analysis, without taking into account the individual patient’s need for it. However, in recent years, more and more attention is paid to such concepts of IT as, volume, speed of introduction and termination, which was formulated in the concept of R.O.S.E. Woman during pregnancy and postpartum period have a number of physiological characteristics that make their own changes in the approach to IT, and the R.O.S.E. needs modification for postpartum hemorrhage.