Preservation of fertility in men with brain tumors

Astaf'eva L.I.; Zhukov O.B.; Kadashev B.A.; Klochkova I.S.; Kobiakov G.L.; Poddubskiy A.A.; Sidnevа Yu.G.; Sharipov O.I.; Kalinina E.A.; Kalinin P.L.

doi:https://doi.org/10.17116/repro20192501174

Astaf'eva L.I.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Zhukov O.B.

Peoples’ Friendship University of Russia, Moscow, Russia;
European Medical Center, Moscow, Russia

Kadashev B.A.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Klochkova I.S.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

Kobiakov G.L.

GBU NII neĭrokhirurgii im. N.N. Burdenko

Poddubskiy A.A.

Burdenko Neurosurgical Institute, Moscow, Russia

Sidnevа Yu.G.

Clinical and Research Institute of Emergency Children’s Surgery and Traumatology, Moscow Health Department, Moscow, Russia

Sharipov O.I.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

Kalinina E.A.

V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow

Kalinin P.L.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Preservation of fertility in men with brain tumors

Authors:

Astaf'eva L.I., Zhukov O.B., Kadashev B.A., Klochkova I.S., Kobiakov G.L., Poddubskiy A.A., Sidnevа Yu.G., Sharipov O.I., Kalinina E.A., Kalinin P.L.

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Journal: Russian Journal of Human Reproduction. 2019;25(1): 74‑82

DOI: 10.17116/repro20192501174

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To cite this article:

Astaf'eva LI, Zhukov OB, Kadashev BA, et al. Preservation of fertility in men with brain tumors. Russian Journal of Human Reproduction. 2019;25(1):74‑82. (In Russ.)
https://doi.org/10.17116/repro20192501174

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)

Использование инфографики авторами научных работ

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Abstract:

ABSTRACT Currently, there is a steady increase in the number of oncological diseases, including the central nervous system (CNS). The number of newly diagnosed tumors of the central nervous system annually grows by 1—2%. However, the progress achieved in clinical neuro-oncology over the past decades has allowed a significant increase in patient survival rates without deterioration in the quality of life. The largest number of patients with brain tumors are people of reproductive age who are interested in maintaining fertility. Despite the improvement of neurosurgical techniques and radiation therapy, the use of modern chemotherapy regimens, patients still have the risk of reducing reproductive potential in the outcome of treatment. One of the most reliable methods for preserving male fertility is currently cryopreservation of sperm. It is important to inform patients with brain tumors about the possible risk of hypogonadism, infertility and the possibility of cryopreservation of sperm, which increases the chances of having genetic progeny in the future.

Keywords:

hypogonadism

male infertility

brain tumors

tumors of the hypothalamic-pituitary region

cryopreservation of sperm

Authors:

Astaf'eva L.I.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Zhukov O.B.

Peoples’ Friendship University of Russia, Moscow, Russia;
European Medical Center, Moscow, Russia

Kadashev B.A.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Klochkova I.S.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

Kobiakov G.L.

GBU NII neĭrokhirurgii im. N.N. Burdenko

Poddubskiy A.A.

Burdenko Neurosurgical Institute, Moscow, Russia

Sidnevа Yu.G.

Clinical and Research Institute of Emergency Children’s Surgery and Traumatology, Moscow Health Department, Moscow, Russia

Sharipov O.I.

Burdenko Neurosurgical Institute, Moscow, Russian Federation

Kalinina E.A.

V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow

Kalinin P.L.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

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