In search for new drugs nanomedicine and nanopharmacologyis rapidly developing. The drugs based on silver nanoparticles (AgNPs) take the leading position in this process. The purpose of the work is to provide analysis and generatiozation of literature data about AgNPs impact on the environment and human health, oocytes and embryos as well as the collect data on possible mechanisms of AgNPs action. Despite existing literature data give grounds to confirm that despite the promising potential for the use of AgNPs in medicine as well as the conducted toxicological studies AgNPs, it is still difficult to make univocal conclusion about the extent of their impact on the human body. These data confirm that the oocytes and embryos make a sensitive system for studies involving nanotoxicology, which can be visualized by thin-effects. Using this test system in the future will contribute to a deeper understanding of the possible effects of nanoparticles on female reproduction.