The polycystic ovary syndrome in patients with diabetes mellitus type i

The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Search result: 0

Grigorian O.R.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia Rossii, Moskva

Grodnitskaia E.É.

Tsentr planirovaniia sem'i i reproduktsii Departamenta zdravookhraneniia, Moskva

Kurtser M.A.

Tsentr planirovaniia sem'i i reproduktsii DZ Moskvy

Melnichenko G.A.

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia;
Endocrinology Research Center, Ministry of Health of Russia, Moscow, Russia

Dedov I.I.

Endocrinology Research Centre

The polycystic ovary syndrome in patients with diabetes mellitus type i

Authors:

Grigorian O.R., Grodnitskaia E.É., Kurtser M.A., Melnichenko G.A., Dedov I.I.

More about the authors

Journal: Russian Journal of Human Reproduction. 2012;(3): 34‑36

Views: 2791

Downloaded: 68

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Grigorian OR, Grodnitskaia EÉ, Kurtser MA, Melnichenko GA, Dedov II. The polycystic ovary syndrome in patients with diabetes mellitus type i. Russian Journal of Human Reproduction. 2012;(3):34‑36. (In Russ.)

Close metadata

Women with diabetes mellitus type 1 (DM1) and polycystic ovary syndrome (PCOS) have normal level of sex hormone binding globulin, suggesting that the pathophysiology of hyperandrogenism in PCOS patients with DM1 appears to be different from that in PCOS without DM1. Hirsutism is less severe and oligomenorrhea is less common in women with DM1 and PCOS compared with nondiabetic PCOS women. Physicians treating women with DM1 should be aware of the risk of hyperandrogenism and should include evaluation of hirsutism, menstrual abnormalities, and biochemical hyperandrogenism into routine examinations. Future studies are needed to determine the best preventive and therapeutic options for the hyperandrogenism in these patients.

Keywords:

polycystic ovary syndrome

diabetes mellitus type

Authors:

Grigorian O.R.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia Rossii, Moskva

Grodnitskaia E.É.

Tsentr planirovaniia sem'i i reproduktsii Departamenta zdravookhraneniia, Moskva

Kurtser M.A.

Tsentr planirovaniia sem'i i reproduktsii DZ Moskvy

Melnichenko G.A.

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia;
Endocrinology Research Center, Ministry of Health of Russia, Moscow, Russia

Dedov I.I.

Endocrinology Research Centre

List of references:

Codner E., Mook-Kanamori D., Bazaes R.A., Unanue N., Sovino H., Ugarte F., Avila A., Iniguez G., Cassorla F. Ovarian function during puberty in girls with type 1 diabetes mellitus: response to leuprolide. J Clin Endocrinol Metab 2005; 90: 3939-3945.
Codner E., Soto N., Lopez P., Trejo L., Avila A., Eyzaguirre F. C., Iniguez G., Cassorla F. Diagnostic criteria for polycystic ovary syndrome and ovarian morphology in women with type 1 diabetes mellitus. J Clin Endocrinol Metab 2006; 91: 2250-2256.
Djursing H., Nyholm H.C., Hagen C., Carstensen L., Pedersen L.M. Clinical and hormonal characteristics in women with anovulation and insulin-treated diabetes mellitus. Am J Obstet Gynecol 1982; 143: 876-882.
Ehrmann D.A., Barnes R.B., Rosenfield R.L. Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion. Endocr Rev 1995; 16: 322-353.
Ehrmann D.A., Rosenfield R.L., Barnes R.B., Brigell D.F., Sheikh Z. Detection of functional ovarian hyperandrogenism in women with androgen excess. N Engl J Med 1992; 327: 157-162.
Escobar-Morreale H.F., Roldan B., Barrio R., Alonso M., Sancho J., de la Calle H., Garcia-Robles R. High prevalence of the polycystic ovary syndrome and hirsutism in women with type 1 diabetes mellitus. J Clin Endocrinol Metab 2000; 85: 4182-4187.
Pedersen O., Beck-Nielsen H. Insulin resistance and insulin-dependent diabetes mellitus. Diabetes Care 1987; 10: 516-523.
Roldan B., Escobar-Morreale H.F., Barrio R., de La Calle H., Alonso M., Garcia-Robles R., Sancho J. Identification of the source of androgen excess in hyperandrogenic type 1 diabetic patients. Diabetes Care 2001; 24: 1297-1299.
Rosenfield R.L. Evidence that idiopathic functional adrenal hyperandrogenism is caused by dysregulation of adrenal steroidogenesis and that hyperinsulinemia may be involved. J Clin Endocrinol Metab 1996; 81: 878-880.
Rudberg S., Persson B. Indications of low sex hormone binding globulin (SHBG) in young females with type 1 diabetes, and an independent association to microalbuminuria. Diabet Med 1995; 12: 816-822.
Salley K.E., Wickham E.P., Cheang K.I., Essah P.A., Karjane N.W., Nestler J.E. Glucose intolerance in polycystic ovary syndrome - a position statement of the Androgen Excess Society. J Clin Endocrinol Metab 2007; 92: 12: 4546-4556.
The Diabetes Control, Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329: 977-986.
The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004; 81:19-25.
Virdis R., Zampolli M., Street M. E., Vanelli M., Potau N., Terzi C., Ghizzoni L., Ibanez L. Ovarian 17-hydroxyprogesterone responses to GnRH analog testing in oligomenorrheic insulin-dependent diabetic adolescents. Eur J Endocrinol 1997; 136: 624-629.

Close metadata

Log in to the site using your account in one of the services

Registration

Last Name

Name

Middle Name

E-mail

Phone

Address

Country

Zip

City

Region

Street

Home

Apartmen

Legal entity name

ИНН

КПП

Password

Password

Repeat password

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.