RELEVANCE

The results of our own research on the effectiveness and safety of isolated intradermal administration of IAL-system ACP in the periorbital area are presented.

OBJECTIVE

To evaluate the safety and effectiveness in different age groups of the biorevitalization technique in the periorbital area with IAL-System ACP (Fidia Farmaceutici S.p.A, Italy).

MATERIAL AND METHODS

There were 30 women over the age of 30 under observation, who were divided into three age groups: the 1st group — 10 women aged 30-43 years; the 2nd group — 10 women aged 44-55 years; the 3rd group — 10 women aged 56 years and older. The patients underwent intradermal administration of IAL-System ACP according to the following scheme: 1 ml of the drug intradermally micropapularly in the area of the lower eyelid and the fixed upper eyelid.

RESULTS

It was found that the use of an internal hyaluronic acid ester (using autocrosslinking technology, it was possible to stabilize short molecules of hyaluronic acid with a mass of 200 kDa by internal ester bonds between individual polysaccharide chains) allows for a more prolonged effect and to avoid excessive hydrophilicity, which is especially important for introduction into the periorbital area. According to the results of the study, a statistically significant increase in dermal thickness was obtained in all age groups after the second procedure. The GAIS and PAIS scales showed a high level of satisfaction with the procedure among both doctors and patients, especially in the 1st and 3rd groups of patients.

CONCLUSION

The high efficiency and safety of the method of isolated intradermal administration of the drug IAL-System ACP was noted, which allows us to recommend this procedure as the method of choice for the prevention and correction of age-related changes in the periorbital area.