The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.
Manturova N.E.
Pirogov Russian National Research Medical University
Stupin V.A.
Pirogov Russian National Research Medical University
Silina E.V.
Sechenov First Moscow State Medical University (Sechenov University)
Cerium oxide nanoparticles for surgery, plastic surgery and aesthetic medicine
Journal: Plastic Surgery and Aesthetic Medicine. 2023;(3): 120‑129
Views: 1895
Downloaded: 72
To cite this article:
Manturova NE, Stupin VA, Silina EV. Cerium oxide nanoparticles for surgery, plastic surgery and aesthetic medicine. Plastic Surgery and Aesthetic Medicine.
2023;(3):120‑129. (In Russ., In Engl.)
https://doi.org/10.17116/plast.hirurgia2023031120
The rapid development of nanotechnology and obtaining high results in the use of metal nanoparticles with variable valence, including cerium oxide nanoparticles (CONPs), makes it necessary to analyze the possibilities of its application for medical purposes.
To review the world literature and study the achievements in the issue of new biological effects of CONPs, which may be useful in the professional work of general and plastic surgeons.
We searched the Scopus and PubMed/Medline databases to July 2023. Inclusion criteria were publications that investigated the role of cerium oxide nanoparticles. According to the Scopus database, there were 15.762 such works, in PubMed — 2.870 (since 1997). Additional filters were chosen for biological activity: antioxidant, anti-inflammatory, antimicrobial action, wound healing, regeneration, surgery, plastic surgery.
It has been shown that the efficiency of CONPs depends on the size and shape of nanoparticles, concentration, chemical composition of the particle surface, surface coating, pH of the medium, and others. The possibilities of creating multicomponent implants with CONPs and cell cultures, including created through 3D printing. Despite the overall significant number of publications about CONPs and the receipt of a large number of encouraging results, the road to the creation of new drugs based on CONPs is just beginning.
An integrated interdisciplinary approach with the interaction of specialists in the fields of chemistry, biophysics, biology, and medicine will overcome difficulties by creating a new smart connection that can form the basis of several series of different medical devices, highly effective drugs and bionanotechnologies, including for general and plastic surgery, cosmetologists and aesthetic medicine.
Keywords:
Authors:
Manturova N.E.
Pirogov Russian National Research Medical University
Stupin V.A.
Pirogov Russian National Research Medical University
Silina E.V.
Sechenov First Moscow State Medical University (Sechenov University)
List of references:
Close metadata
Email Confirmation
An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.
Email Confirmation
Log in to the site using your account in one of the services
We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.