Epidemiology of corpus uteri cancer in women of reproductive age in the Siberian Federal District

Zhuikova L.D.; Ananina O.A.; Kolomiets L.A.; Kononova G.A.; Ukraintseva E.A.; Pikalova L.V.; Ochirov M.O.; Zhuikova A.S.

doi:https://doi.org/10.17116/onkolog20251401136

Zhuikova L.D.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0003-3536-8473

Ananina O.A.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0001-8002-3189

Kolomiets L.A.

Oncology Research Institute — Tomsk National Research Medical Center;
Siberian State Medical University

ORCID: 0000-0002-6854-8940

Kononova G.A.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0001-6010-6462

Ukraintseva E.A.

Altai Regional Oncology Dispensary

ORCID: 0009-0007-2135-3234

Pikalova L.V.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0003-1453-2254

Ochirov M.O.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0001-6628-2918

Zhuikova A.S.

Siberian State Medical University

ORCID: 0009-0006-7784-9442

Epidemiology of corpus uteri cancer in women of reproductive age in the Siberian Federal District

Authors:

Zhuikova L.D., Ananina O.A., Kolomiets L.A., Kononova G.A., Ukraintseva E.A., Pikalova L.V., Ochirov M.O., Zhuikova A.S.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2025;14(1): 36‑41

DOI: 10.17116/onkolog20251401136

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To cite this article:

Zhuikova LD, Ananina OA, Kolomiets LA, et al. . Epidemiology of corpus uteri cancer in women of reproductive age in the Siberian Federal District. P.A. Herzen Journal of Oncology. 2025;14(1):36‑41. (In Russ.)
https://doi.org/10.17116/onkolog20251401136

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)

Использование инфографики авторами научных работ

Abstract:

OBJECTIVE

To analyze the corpus uteri cancer incidence rates and cancer care quality in reproductive-age women residing in the territories of the Siberian Federal District (SFD).

MATERIAL AND METHODS

Specialized form No. 7 «Report on diseases of malignant neoplasms» and form No. 35 «Information on patients with malignant neoplasms» for the period 2013—2022 were analyzed.

RESULTS

In the SFD (2022), in the structure of oncological morbidity among women of reproductive age (15—49 years), uterine cancer ranked 6^th with a specific weight of 5.7%. From 2013 to 2022, the age-standardized incidence rate (ASR World per 100, 000 ) increased from 16.2±0.3 to 19.7±0.4, there was no statistically significant increase in reproductive age (9.3±0.5, 2022). The level of early diagnosis (stage I-II) increased both in the federal District generally (from 73.7 to 84.1%) and in most of its regions. The proportion of advanced cases (stage IV) in the SFD has not changed (6.6%, 2022).

The contingent accumulation index increased both on average in the SFD (from 9.4 to 10.2) and in in separate regions. According to the SFD, there is a positive decrease in the 1-year mortality rate from 9.9 to 8.3% and an increase in the proportion of patients registered for 5 years or more from 59.6 to 65.6%.

CONCLUSION

In the Siberian Federal District, there is an increase in the corpus uteri cancer incidence in general, among women of reproductive age the indicators are stable. Most quality cancer care parameters have improved over time, with the exception of advanced stage cancer. Measures for early detection and effective treatment of corpus uteri cancer need to be improved.

Keywords:

corpus uteri cancer

reproductive age

cancer incidence

cancer care

Siberian Federal District

Authors:

Zhuikova L.D.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0003-3536-8473

Ananina O.A.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0001-8002-3189

Kolomiets L.A.

Oncology Research Institute — Tomsk National Research Medical Center;
Siberian State Medical University

ORCID: 0000-0002-6854-8940

Kononova G.A.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0001-6010-6462

Ukraintseva E.A.

Altai Regional Oncology Dispensary

ORCID: 0009-0007-2135-3234

Pikalova L.V.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0003-1453-2254

Ochirov M.O.

Oncology Research Institute — Tomsk National Research Medical Center

ORCID: 0000-0001-6628-2918

Zhuikova A.S.

Siberian State Medical University

ORCID: 0009-0006-7784-9442

Received:

13.02.2024

Accepted:

19.03.2024

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References:

World Health Organization. The global health observatory. Explore a world of health data. Women of reproductive age (15—49 years) population (thousands). (Accessed January 31, 2024). Available at: https://www.who.int/data/gho/indicator-metadata-registry/imr-details/women-of-reproductive-age-(15—49-years)-population-(thousands)
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-249. https://doi.org/10.3322/caac.21660
Kaprin AD, Starinskii VV, Shakhzadova AO, eds. The state of cancer care for the Russian population in 2022. Moscow: MNIOI named after P.A. Herzen — a branch of the Federal State Budgetary Institution «National Medical Research Center of Radiology» of the Ministry of Health of the Russian Federation; 2023. 254p. (In Russ.).
Zhuikova LD, Choinzonov EL, Ananina OA, Pikalova LV, Kononova GA. The prevalence of oncological diseases among the population of the region in Siberia and the Far East. Health Care of the Russian Federation. 2023;67(1):64-71. (In Russ.). https://doi.org/10.47470/0044-197X-2023-67-1-64-71
Burton ER, Sorosky JI. Recognition and therapeutic options for malignancy of the cervix and uterus. Obstet Gynecol Clin North Am. 2017;44(2):195-206. https://doi.org/10.1016/j.ogc.2017.02.009
Bohîlțea RE, Furtunescu F, Dosius M, Cîrstoiu M, Radoi V, Baroș A, Bohîlțea LC. Evaluation of endometrial cancer epidemiology in Romania. J Med Life. 2015;8(2):218-225.
National Cancer Institute. Surveillance, Epidemiology and End Results Program. Cancer statistics explore network. SEER*Explorer. Updated November 5, 2024. https://seer.cancer.gov/statistics-network/explorer
Klinyshkova T. Clinical and epidemiological features of corpus uteri cancer. Vrach. 2020;31(2):41-44. (In Russ.). https://doi.org/10.29296/25877305-2020-02-09
Sil’kina MO, Sosnova EA. Organ-preserving treatment in gynecological types of cancer. V.F. Snegirev Archives of Obstetrics and Gynecology. 2019;6(1):4-7. (In Russ.). https://doi.org/10.18821/2313-8726-2019-6-1-4-7
Chernyakov AA, Chernyshova AL, Kolomiets LA, Trushchuk YuM, Dil’ OS, Krasil’nikov SE, Antipov VA, Shumeikina AO, Chernyshova AE. Endometrial cancer and pregnancy. Obstetrics and Gynecology. 2023;(12):40-46. (In Russ.). https://doi.org/10.18565/aig.2023.178
Frolova NI, Belokrinitskaya TE, Barkan TM, Golygin EV, Liga VF, Pletneva VA, Plotkin IB, Potapova EN, Tarbaeva DA, Khaven’ TF, Fal’ko EV, Shemyakina KN. Medical and social characteristics of women of young reproductive age after hysterectomy. Acta Biomedica Scientifica. 2018;3(4):15-20. (In Russ.). https://doi.org/10.29413/ABS.2018-3.4.2
Zhuikova LD, Ananina OA, Sirotina AS, Pikalova LV, Fokin VA, Kononova GA. Disability-Adjusted Life Year (DALY) assessment and economic damage from premature death of cervical uterine and ovarian cancers in the Tomsk Region. Journal of Modern Oncology. 2022;24(4):494-498. (In Russ.). https://doi.org/10.26442/18151434.2022.4.201709
Chernyshova AL, Kolomiets LA, Trushchuk YuM, Dil’ OS, Chernov VI, Marchenko ES, Chekalkin TL, Antipov VA, Krasil’nikov SE. Assessment of reproductive outcomes and quality of life in patients after radical trachelectomy. Tumors of Female Reproductive System. 2022;18(2):77-85. (In Russ.). https://doi.org/10.17650/1994-4098-2022-18-2-77-85
The Federal State Statistics Service. Population of the Russian Federation by gender and age. Available at: https://rosstat.gov.ru/compendium/document/13284(InRuss.).
Petrova GV, Gretsova OP, Kaprin AD, Starinskii VV. Characteristics and methods of calculating medical and statistical indicators used in oncology. Moscow: P.A. Hertzen Moscow Oncology Research Institute of the Ministry of Health of the Russian Federation; 2014. (In Russ.).