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Plekhanova O.S.

Ural State Medical University;
JSC Medsi Group

Tsvirenko S.V.

Ural State Medical University

Kalacheva O.S.

JSC Medsi Group

Saveliev L.I.

Ural State Medical University;
Regional Children Hospital;
Research Institute of Medical Cell Technologies

Principles of methods for indirect determination of reference intervals

Authors:

Plekhanova O.S., Tsvirenko S.V., Kalacheva O.S., Saveliev L.I.

More about the authors

Journal: Laboratory Service. 2022;11(2): 27‑39

DOI: 10.17116/labs20221102127

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To cite this article:

Plekhanova OS, Tsvirenko SV, Kalacheva OS, Saveliev LI. Principles of methods for indirect determination of reference intervals. Laboratory Service. 2022;11(2):27‑39. (In Russ.)
https://doi.org/10.17116/labs20221102127

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In the face of difficulties in recruiting groups to establish reference intervals by a direct method, it is possible to use indirect methods for calculating. The indirect definition of RI involves working with databases of medical organizations. The main object of research is data on the values of analytes of biochemical, hematological, immunological studies for long period. In the article the main methods of calculation, their principles, conditions of use and properties are discussed.

Keywords:

reference intervals
indirect methods

Authors:

Plekhanova O.S.

Ural State Medical University;
JSC Medsi Group

Tsvirenko S.V.

Ural State Medical University

Kalacheva O.S.

JSC Medsi Group

Saveliev L.I.

Ural State Medical University;
Regional Children Hospital;
Research Institute of Medical Cell Technologies

Received:

10.04.2022

Accepted:

11.05.2022

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