Nosocomial bloodstream infections due to Candida spp. are associated with high morbidity and mortality among adults and children in many countries of the world, which is mainly due to imperfect diagnosis of such infections, untimely and inadequate therapy. The own database on the taxonomic structure of pathogens, the frequency of their resistance to antimycotics creates optimal conditions for adequate and timely empirical treatment. The aim of the study was to determine the main species of Candida spp. in fungemia, the level of resistance to fluconazole and voriconazole. Materials and methods. 440 positive blood cultures from 261 oncology patients (75 children and 186 adults) were analyzed. BD BACTEC FX 400 («Becton Dickinson», USA) and Bact/ALERT 3D («BioMerieux», France) were used to incubate the blood cultures. The identification was carried out on a MALDI-TOF Microflex LT instrument (Biotyper, «Bruker Daltonics», Germany). Sensitivity to fluconazole and voriconazole was determined on a VITEK 2 instrument («BioMerieux», France). Results. In general, C. parapsilosis (51.1%) was the first in candidemia, C. albicans (21.5%) in the second, and C. guilliermondii (7.4%) in the third. In adults statistically significantly more C. parapsilosis was detected than C. albicans (56.5%, 18.5%, respectively, p<0.0001). In children, there were no significant differences in the incidence of C. parapsilosis and C. albicans. The sensitivity of 242 strains of 10 Candida species is estimated. In general, resistance to fluconazole (57.9%) is statistically significantly higher than voriconazole resistance (46.3%, p<0.02). Statistically significantly more resistant strains to fluconazole and voriconazole were isolated from adults (90.9%, 92.6%, respectively, p<0.0001). The proportion of strains resistant to fluconazole, but sensitive to voriconazole was 21.9%. Conclusions. In general, in the taxonomic structure of candidemia, C. parapsilosis ranks first, C. albicans on the second, C. guilliermondii on the third. The taxonomic structure of pathogens is similar for adults and children, but the leading species are different. In adult patients, resistance of Candida spp. to fluconazole is statistically significantly higher in comparison with voriconazole. For children statistically significant differences in the resistance of Candida spp. to fluconazole and voriconazole were not observed.