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Negasheva E.S.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia

Frigo N.V.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia;
State Research Center — Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia

Kitaeva N.V.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia

Dmitriev G.A.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia;
Moscow Scientific Research Institute for Epidemiology and Microbiology named after G.N. Gabrichevsky Federal Service for Supervision of Consumer Rights Protection and Human Well-being, Moscow, Russia

Smerdova M.A.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia

Mardanly S.G.

State University of Humanities and Technology, Orekhovo-Zuevo, Russia;
Joint Stock Company «EKOlab», Elektrogorsk, Russia

Laboratory diagnosis of gonococcal infection. Modern aspects (literature review)

Authors:

Negasheva E.S., Frigo N.V., Kitaeva N.V., Dmitriev G.A., Smerdova M.A., Mardanly S.G.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2026;25(2): 178‑186

DOI: 10.17116/klinderma202625021178

Read: 313 times

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Table of contents

LABORATORY DIAGNOSIS OF GONOCOCCAL INFECTION. MODERN ASPECTS (LITERATURE REVIEW)
LABORATORY DIAGNOSIS OF GONOCOCCAL INFECTION. MODERN ASPECTS (LITERATURE REVIEW)

To cite this article:

Negasheva ES, Frigo NV, Kitaeva NV, Dmitriev GA, Smerdova MA, Mardanly SG. Laboratory diagnosis of gonococcal infection. Modern aspects (literature review). Russian Journal of Clinical Dermatology and Venereology. 2026;25(2):178‑186. (In Russ.)
https://doi.org/10.17116/klinderma202625021178

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Gonococcal infection is one of the most common sexually transmitted infections in the world. According to WHO estimates, 86.9 million cases of gonococcal infection were reported worldwide among adults aged 15—49 years in 2016. The article is a literature review on current approaches to diagnosis of gonococcal infection. It was noted that currently priority in the diagnosis of gonococcal infection is given to the techniques of nucleic acid amplification, which have some important advantages compared to other methods (microscopy, culture, POC-tests), namely: high sensitivity and specificity, lack of need for a live pathogen, possibility of simultaneous identification of several pathogens in one sample of biomaterials and quantification of DNA/RNA pathogens (Real-time PCR) or bacterial load, as well as quickness of the result achievement (compared to culture technique). Microscopy method can be used for diagnosis of gonococcal infection in men with symptoms as well as (in other cases) for general assessment of swab morphology. Culture-based study (bacterial culture test) is preserved in the arsenal of methods of laboratory diagnosis of gonococcal infection; diagnosis of gonococcal infection in children, extragenital localization and asymptomatic course of the disease are the priority indications for its use.

Keywords:

sexually transmitted infections
gonococcal infection
N.gonorrhoeae
laboratory diagnosis

Authors:

Negasheva E.S.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia

Frigo N.V.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia;
State Research Center — Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia

Kitaeva N.V.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia

Dmitriev G.A.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia;
Moscow Scientific Research Institute for Epidemiology and Microbiology named after G.N. Gabrichevsky Federal Service for Supervision of Consumer Rights Protection and Human Well-being, Moscow, Russia

Smerdova M.A.

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia

Mardanly S.G.

State University of Humanities and Technology, Orekhovo-Zuevo, Russia;
Joint Stock Company «EKOlab», Elektrogorsk, Russia

Received:

02.10.2025

Accepted:

09.01.2026

Close metadata

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